公开(公告)号：US09216107B2

公开(公告)日：2015-12-22

申请号：US14591587

申请日：2015-01-07

Applicant: Transcend Medical, Inc.

Inventor： Thomas A. Silvestrini ,  Richard S. Lilly

IPC: A61F9/00 ,  A61B1/07 ,  A61B1/04 ,  A61F9/007 ,  A61F9/008 ,  A61B1/00 ,  A61B1/06

CPC classification number: A61F9/00781 ,  A61B1/00165 ,  A61B1/04 ,  A61B1/051 ,  A61B1/06 ,  A61B1/0646 ,  A61B1/07 ,  A61B5/0086 ,  A61B2090/309 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/00736 ,  A61F9/008 ,  A61F2220/0033

Abstract: Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier.

公开(公告)号：US20140364789A1

公开(公告)日：2014-12-11

申请号：US14283759

申请日：2014-05-21

Applicant: Transcend Medical, Inc.

Inventor： Michael Schaller

IPC: A61F9/007 ,  B05D1/00

CPC classification number: A61F9/00781 ,  A61F2/0077 ,  A61F2002/0081 ,  A61F2250/0026

Abstract: Disclosed are devices and methods for treatment of eye disease such as glaucoma. Implants are described herein that create a flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space. In addition, the implant can be treated with one or more treatments, including plasma treatments, for creating a variety of surface features and characteristics. Some of the surface features and characteristics can assist in controlling tissue responses to the implanted implant, including promoting or preventing tissue proliferation.

Abstract translation: 公开了用于治疗诸如青光眼之类的眼部疾病的装置和方法。 本文描述了植入物，其形成流场，例如在前房与上腔空间或脉管外空间之间。 此外，可以通过一种或多种处理（包括等离子体处理）来处理植入物，以产生各种表面特征和特征。 一些表面特征和特征可以帮助控制植入植入物的组织反应，包括促进或预防组织增生。

公开(公告)号：US20140213958A1

公开(公告)日：2014-07-31

申请号：US14163364

申请日：2014-01-24

Applicant: Transcend Medical, Inc.

Inventor： Luke Clauson ,  Michael Schaller

IPC: A61F9/007

CPC classification number: A61F9/00781

Abstract: This disclosure relates generally to methods and devices for an ocular implant which can be positioned in the Schlemm's canal of a patient's eye for improving fluid flow, such as aqueous fluid, through the eye. The ocular implant can have a variety of shapes and sizes which can allow the ocular implant to be implanted in the Schlemm's canal for applying a force, including a predetermined force, along a part of the Schlemm's canal. The force applied by the ocular implant can change the shape of the Schlemm's canal which can increase the flow volume within and through the Schlemm's canal.

Abstract translation: 本公开一般涉及用于眼部植入物的方法和装置，其可以定位在患者眼睛的施莱姆氏管中，以通过眼睛改善流体流动，例如水性流体。 眼部植入物可以具有各种形状和尺寸，其可以允许将眼部植入物植入施莱姆氏管，以施加包括预定力在内的Schlemm管的一部分的力。 由眼部植入物施加的力可以改变施莱姆氏管的形状，这可以增加施勒姆管内和通过施莱姆氏管的流量。

公开(公告)号：US20140066831A1

公开(公告)日：2014-03-06

申请号：US14071500

申请日：2013-11-04

Applicant: Thomas A. Silvestrini ,  Eugene de Juan, JR.

Inventor： Thomas A. Silvestrini ,  Eugene de Juan, JR.

IPC: A61F9/007

CPC classification number: A61F9/00781 ,  A61F2210/0019

Abstract: Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume.

Abstract translation: 本文描述了用于治疗眼睛状况的装置和方法。 描述了一种眼部植入物，其包括具有形成流动路径的内部内腔的细长构件，与流动通道连通的至少一个流入口以及与流动通路连通的至少一个流出口。 细长构件适于定位在眼睛中，使得至少一个流入端口与前房连通，至少一个流出端口与脉管外空间连通，以在前房和脉管外空间之间提供流体通路，当细长 成员植入眼睛。 细长构件具有赋予细长构件刚性的壁材料。 选择刚度使得在植入之后，细长构件使围绕脉管外空间的眼组织变形，形成帐篷体积。

公开(公告)号：US20130253407A1

公开(公告)日：2013-09-26

申请号：US13897313

申请日：2013-05-17

Applicant: Transcend Medical, Inc.

Inventor： Michael Yablonski

IPC: A61F9/007

CPC classification number: A61F9/00781 ,  A61M1/36 ,  A61M27/00

Abstract: A surgical technique and device wherein an indwelling tube is placed in the eye of a patient having glaucoma. The tube diverts aqueous humor from the anterior chamber to the suprachoroidal space from which it is removed by blood flowing in the choroidal and uveal tissues. This decreases the intraocular pressure.

公开(公告)号：US08486000B2

公开(公告)日：2013-07-16

申请号：US10579330

申请日：2004-11-12

Applicant: Minas Theodore Coroneo

Inventor： Minas Theodore Coroneo

IPC: A61M5/00

CPC classification number: A61F9/00781 ,  A61F2/148

Abstract: This invention comprises a flexible ocular device for implantation into the eye formed of a biocompatible elastomeric material, foldable to a diameter of 1.5 mm or less, comprising a fluid drainage tube having at one end a foldable plate adapted to located the device on the inner surface of the sclera in a suprachoroidal space formed by cyclodialyis, said drainage tube opening on to the disc at one end and opening to the anterior chamber when implanted into the eye at its other end, so as to provide aqueous pressure regulation. Also provided are methods for the treatment of glaucoma utilizing the flexible ocular device, and an ocular pressure spike shunt.

Abstract translation: 本发明包括用于植入眼睛的柔性眼部装置，其由可生物相容的弹性体材料形成，可折叠到直径为1.5mm或更小，包括流体排出管，其一端具有适于将装置定位在内表面上的折叠板 在通过环状透明膜形成的脉络膜上空间中的巩膜，所述引流管在一端开放到椎间盘并在其另一端植入眼睛时通向前房，以提供水压调节。 还提供了使用柔性眼部装置治疗青光眼和眼压尖峰分流的方法。

公开(公告)号：US20130110125A1

公开(公告)日：2013-05-02

申请号：US13721941

申请日：2012-12-20

Applicant: Transcend Medical, Inc.

Inventor： Thomas A. Silvestrini ,  Richard S. Lilly

IPC: A61F9/00

CPC classification number: A61F9/00781 ,  A61B1/00165 ,  A61B1/04 ,  A61B1/051 ,  A61B1/06 ,  A61B1/0646 ,  A61B1/07 ,  A61B5/0086 ,  A61B2090/309 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/00736 ,  A61F9/008 ,  A61F2220/0033

Abstract: Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier.

公开(公告)号：US08945038B2

公开(公告)日：2015-02-03

申请号：US13897313

申请日：2013-05-17

Applicant: Transcend Medical, Inc.

Inventor： Michael Yablonski

IPC: A61M5/00 ,  A61F9/007 ,  A61F9/00

CPC classification number: A61F9/00781 ,  A61M1/36 ,  A61M27/00

Abstract: A surgical technique and device wherein an indwelling tube is placed in the eye of a patient having glaucoma. The tube diverts aqueous humor from the anterior chamber to the suprachoroidal space from which it is removed by blood flowing in the choroidal and uveal tissues. This decreases the intraocular pressure.

Abstract translation: 一种手术技术和装置，其中留置管置于患有青光眼的患者的眼睛中。 管将房水从前房转移到脉络膜上空间，通过在脉络膜和葡萄膜组织中流动的血液将其从其中除去。 这降低了眼内压。

公开(公告)号：US20140309599A1

公开(公告)日：2014-10-16

申请号：US14254366

申请日：2014-04-16

Applicant: TRANSCEND MEDICAL, INC.

Inventor： Michael Schaller

IPC: A61F9/00

CPC classification number: A61F9/0008 ,  A61F9/0017 ,  A61M5/31526 ,  A61M2005/2407 ,  A61M2005/3143

Abstract: This disclosure relates generally to an injection device having a plunger configured to advance a distance into a container of material, such as a viscoelastic container; a trigger mechanism configured upon an actuation of the trigger mechanism to apply a first force to a spring element; and the spring element coupled to the plunger and configured to apply a second force to the plunger and which is configured to prevent exceeding a threshold maximum force applied to the container.

Abstract translation: 本公开总体上涉及具有柱塞的注射装置，所述柱塞构造成将距离推进到诸如粘弹性容器的材料容器中; 触发机构，其在触发机构的致动下构造，以向弹簧元件施加第一力; 并且所述弹簧元件联接到所述柱塞并且构造成向所述柱塞施加第二力，并且被配置为防止超过施加到所述容器的阈值最大力。

公开(公告)号：US20140188030A1

公开(公告)日：2014-07-03

申请号：US14199737

申请日：2014-03-06

Applicant: Transcend Medical, Inc.

Inventor： Minas Theodore Coroneo

IPC: A61F9/007

CPC classification number: A61F9/00781 ,  A61F2/148

Abstract: Disclosed are devices and methods of treating an ocular disorder including forming a self-sealing incision in a cornea into an anterior chamber of an eye; introducing through the incision a fluid drainage tube having a distal end, a proximal end and a longitudinal, internal lumen extending through the fluid drainage tube, wherein at least the proximal end passes through the anterior chamber; and implanting the distal end of the fluid drainage tube in fluid communication with the suprachoroidal space such that the proximal end of the fluid drainage tube remains in fluid communication with the anterior chamber.

Abstract translation: 公开了治疗眼部疾病的装置和方法，包括在角膜中形成自密封切口进入眼前房; 通过切口引入流体排出管，其具有延伸穿过流体排出管的远端，近端和纵向内腔，其中至少近端穿过前房; 以及植入所述流体引流管的远端与所述脉管外空间流体连通，使得所述流体引流管的近端保持与所述前房流体连通。