公开(公告)号：US20240352171A1

公开(公告)日：2024-10-24

申请号：US18686531

申请日：2022-08-31

申请人： NOF CORPORATION

发明人： Yoshiki TANAKA ,  Shu TAKASHIMA ,  Norio IWAKIRI

IPC分类号： C08F283/12 ,  C07F9/141 ,  C08G77/442 ,  C08G77/50 ,  G02B1/04

CPC分类号： C08F283/124 ,  C07F9/1411 ,  C08G77/442 ,  C08G77/50 ,  G02B1/043

摘要： An object is to provide a polydimethylsiloxane-containing monomer that exhibits satisfactory compatibility with a hydrophilic monomer and a hydrophilic polymer, in which a polymerization product obtained by polymerizing a composition including the polydimethylsiloxane-containing monomer, the hydrophilic monomer, and the hydrophilic polymer has an anti-lipid adhesion property. It has been recognized that a polydimethylsiloxane-containing monomer having a phosphorylcholine group and a hydroxy group can achieve the object, and thus the present disclosure has been completed.

公开(公告)号：US20240350382A1

公开(公告)日：2024-10-24

申请号：US18683917

申请日：2022-09-21

申请人： NOF CORPORATION

发明人： Megumi SATO ,  Koji SEKIGUCHI

IPC分类号： A61K8/34 ,  A61K8/31 ,  A61Q19/00

CPC分类号： A61K8/342 ,  A61K8/31 ,  A61Q19/00 ,  A61K2800/10

摘要： Provided are a cosmetic oil agent capable of providing good affinity to the skin, powdery feeling with moisture and excellent rinsing property with water and a cosmetic containing the same. The cosmetic oil agent contains 97 to 99.9 mass % of (A) a straight-chain saturated hydrocarbon having a carbon number of 8 to 13, and 0.1 to 3 mass % of (B) a monovalent alcohol having a carbon number of 16 to 24.

公开(公告)号：US20240317998A1

公开(公告)日：2024-09-26

申请号：US18578085

申请日：2022-09-22

申请人： NOF CORPORATION

发明人： Satoru KOMATSUZAKI ,  Naoshi TAKAHASHI

IPC分类号： C08L75/04 ,  C08K3/36 ,  C08K5/10 ,  C08K5/205 ,  C08K7/16 ,  C08K7/18 ,  G02F1/1339

CPC分类号： C08L75/04 ,  C08K3/36 ,  C08K5/10 ,  C08K5/205 ,  C08K7/16 ,  C08K7/18 ,  G02F1/1339 ,  C08K2201/003 ,  G02F2202/023

摘要： A curable resin composition which contains (A) a multifunctional thiol compound having 2 to 6 thiol groups, (B) a multifunctional urethane (meth)acrylate compound having 2 to 3 (meth)acrylic groups, (C) a multifunctional allyl compound having 2 to 4 (meth)allyl groups, (D) a spherical filler that has an average particle diameter of 15 μm or less and (E) a photopolymerization initiator, wherein: the blending mass ratio (B)/(C) is 0.1 to 1.0; the ratio of the thiol groups in the component (A) to the polymerizable unsaturated bonds in the components (B) and (C) is 0.5 to 3.0; and the amount of the component (D) is 1 to 50 parts by mass relative to a total of 100 parts by mass of the components (A) to (C).

公开(公告)号：US20240309131A1

公开(公告)日：2024-09-19

申请号：US18263427

申请日：2022-01-21

申请人： NOF CORPORATION

发明人： Seina KONDO ,  Hirotaka SUZUKI ,  Masaru MATSUDA

IPC分类号： C08F130/02 ,  C08F230/02 ,  C12Q1/6851

CPC分类号： C08F130/02 ,  C08F230/02 ,  C12Q1/6851

摘要： The present invention provides a composition for nucleic acid amplification containing a polymer containing a constitutional unit derived from 2-(meth)acryloyloxyethyl phosphorylcholine.

公开(公告)号：US20240301137A1

公开(公告)日：2024-09-12

申请号：US18577166

申请日：2022-07-06

申请人： NOF CORPORATION ,  TOKYO INSTITUTE OF TECHNOLOGY

发明人： Koichi OGI ,  Junya MICHINISHI ,  Tomoyuki OHTAKE ,  Muneaki IIZUKA ,  Nobuhiro NISHIYAMA ,  Hiroyasu TAKEMOTO ,  Yutaka MIURA ,  Takahiro NOMOTO ,  Makoto MATSUI ,  Yi-Jung SUNG ,  Masahiro TOYODA ,  Aria GHASEMIZADEH

IPC分类号： C08G69/48 ,  C08G69/08 ,  C08G69/46

CPC分类号： C08G69/48 ,  C08G69/08 ,  C08G69/46

摘要： The present invention provides a highly pure pH-responsive polymer represented by the following formula (I), a production method thereof, and the like:




(in the formula (I), each symbol is as described in the specification).

公开(公告)号：US12064513B2

公开(公告)日：2024-08-20

申请号：US17040960

申请日：2019-03-25

申请人： NOF CORPORATION ,  NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY

发明人： Yuta Nakai ,  Kota Tange ,  Hiroki Yoshioka ,  Shinya Tamagawa ,  Hidetaka Akita ,  Hiroki Tanaka ,  Nae Takata ,  Manami Konishi ,  Tatsunari Takahashi

IPC分类号： A61K9/127 ,  A61K47/22 ,  A61K48/00 ,  C07C323/25 ,  C07D211/22 ,  C07D405/14

CPC分类号： A61K9/1272 ,  A61K47/22 ,  A61K48/00 ,  C07C323/25 ,  C07D211/22 ,  C07D405/14

摘要： The invention provides a cationic lipid, a lipid membrane structure containing same, and use thereof. The cationic lipid is represented by the formula (1)




wherein R1a, R1b, R2a, R2b, R3a, R3b, Xa, Xb, Ya, Yb, Za, and Zb are as defined in the specification.

公开(公告)号：US20240168340A1

公开(公告)日：2024-05-23

申请号：US18281874

申请日：2022-03-28

申请人： NOF CORPORATION

发明人： Satoru KOMATSUZAKI

IPC分类号： G02F1/1339

CPC分类号： G02F1/1339

摘要： A curable resin composition for use in a sealing material for film liquid crystal panel, the composition containing: (A) a polyfunctional thiol compound; (B) a polyfunctional (meth)acrylic compound which has 3-6 (meth)acrylic groups and has a (meth)acrylic equivalent of 100-250; (C) a polyfunctional acrylic compound which has 2-4 (meth)acrylic groups; and (D) a photopolymerization initiator. The blending mass ratio of (B)/(C) is 0.1-1.0, and the ratio between thiol groups of(A) and polymerizable unsaturated bonds of (B) and (C) (thiol groups/polymerizable unsaturated bonds) is 0.5-3.0.

公开(公告)号：US11912964B2

公开(公告)日：2024-02-27

申请号：US17275955

申请日：2019-09-11

申请人： NOF CORPORATION

发明人： Hirotaka Suzuki ,  Hiroko Kawasaki ,  Shunsuke Sakurai

IPC分类号： C11D3/37 ,  C08F120/36 ,  C11D11/00 ,  C11D3/26 ,  C11D3/30 ,  C11D3/36

CPC分类号： C11D3/3784 ,  C08F120/36 ,  C11D3/26 ,  C11D3/30 ,  C11D3/36 ,  C11D3/3761 ,  C11D3/3769 ,  C11D3/3773 ,  C11D11/0017 ,  C08F2800/10

摘要： The present invention is a contact lens treatment solution containing the following copolymer A and copolymer B in a ratio of A/B=1000/1 to 2/1 (by weight). According to the present invention, there can be provided a contact lens treatment solution capable of removing dirt having adhered to contact lens surfaces and capable of imparting persisting hydrophilicity to contact lens surfaces, by simple immersion treatment.



Copolymer A: a copolymer obtained by copolymerization of a monomer (a) represented by formula (1) and a monomer (b) represented by formula (2), in which the copolymerization ratio of the monomer (a) to the monomer (b), a/b=7/3 to 9/1 (by mol), and having a weight-average molecular weight of 400,000 to 700,000.
Copolymer B: a copolymer obtained by copolymerization of a monomer (c) represented by formula (3) and a monomer (d) represented by formula (4), in which the copolymerization ratio of the monomer (c) to the monomer (d), c/d=1/4 to 9/1 (by mol), and having a weight-average molecular weight of 20,000 to 90,000.

公开(公告)号：US11905366B2

公开(公告)日：2024-02-20

申请号：US17041102

申请日：2019-03-27

申请人： NOF CORPORATION

发明人： Akihide Onozawa ,  Hiroki Yoshioka ,  Masaki Kamiya

IPC分类号： A61K47/60 ,  C08G65/324 ,  C08G65/325 ,  C08G65/326 ,  C08G65/331 ,  C08G65/333 ,  C08G65/334

CPC分类号： C08G65/324 ,  A61K47/60 ,  C08G65/325 ,  C08G65/326 ,  C08G65/331 ,  C08G65/333 ,  C08G65/334

摘要： A method for producing a multi-arm type polyethylene glycol derivative, which includes carrying out the following in order: Step (A): protecting an even number of hydroxyl groups, while leaving only the hydroxyl group at the 1-position of a polyhydric alcohol having an odd number of hydroxyl groups, other than the hydroxyl group at the 1-position by cyclic benzylidene acetalization, Step (B): linking two molecules of the compound obtained in step (A) to a compound for introducing a specific linker by etherification reaction, Step (C): deprotecting the cyclic benzylidene acetal structure at the terminal of the compound obtained in step (B), Step (D): polymerizing 3 to 600 mol of ethylene oxide to each hydroxyl group of the compound obtained in step (C) to obtain a multi-arm type polyethylene glycol derivative, and Step (E): functionalizing the hydroxyl group at the terminal of the multi-arm type polyethylene glycol derivative obtained in step (D).

公开(公告)号：US20240010777A1

公开(公告)日：2024-01-11

申请号：US18039567

申请日：2021-11-24

申请人： NOF CORPORATION

发明人： Hirotaka SUZUKI ,  Shunsuke OZAKI ,  Norio IWAKIRI

IPC分类号： C08F220/36 ,  G02C7/04

CPC分类号： C08F220/36 ,  G02C7/04

摘要： Provided is a surface treatment agent for an ophthalmic device that can impart wettability and lubricity to the surface of a silicone hydrogel, more specifically, a surface treatment agent for an ophthalmic device that can subject the silicone hydrogel to surface treatment even when the silicone hydrogel is not caused to present any specific complementary functional group. Also provided are a surface-treated silicone hydrogel whose surface has been treated with the surface treatment agent for an ophthalmic device, and an ophthalmic device using the surface-treated silicone hydrogel. It has been found that the above-mentioned objects can be achieved by using a water-soluble copolymer obtained by copolymerizing a phosphorylcholine group-containing monomer, a specific silicone monomer, and a thermally reactive monomer or a photoreactive monomer, the copolymer having water solubility controlled to a specific level. Thus, the present invention has been completed.