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公开(公告)号：US08828001B2
公开(公告)日：2014-09-09
申请号：US12064276
申请日：2008-02-15
Applicant: Stanley D. Stearns , H. Max Loy, Jr.
Inventor： Stanley D. Stearns , H. Max Loy, Jr.
CPC classification number: A61B17/1642 , A61B17/3472 , A61B2017/003 , Y10T408/568 , Y10T408/665
Abstract: A minimally invasive and particularly small apparatus for drilling into bone and for providing for delivery of medical treatment is provided. The directional drilling apparatus includes a miniature shaft, a bit, first shaft-mounted thrust ring, second shaft-mounted thrust ring, a tubing jacket surrounding the shaft and intermediate the first and second shaft-mounted thrust rings, and a guide tube encapsulating the tubing jacket. As a result, a hole, targeted towards a cancerous lesion within the bone, is possible. After removal of the shaft and the tubing jacket, treatment may be introduced through the particularly small passage created by the directional drilling apparatus or through the passage via a capillary inserted through at least a portion of the guide tube and the passage, which guide tube may include a hypodermic needle.
Abstract translation: 提供了一种用于钻入骨骼并提供医疗处理的微创特别小的装置。 定向钻井设备包括微型轴，钻头，第一轴安装推力环，第二轴安装的推力环，围绕轴并且在第一和第二轴安装推力环之间的管套，以及封装 管夹套。 因此，可以有一个针对骨内癌变病变的孔。 在移除轴和管套之后，处理可以通过由定向钻井设备产生的特别小的通道引入，或者通过经由插入穿过导管和通道的至少一部分的毛细管的通道引入，该导管可以 包括皮下注射针。
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公开(公告)号：US08529516B2
公开(公告)日：2013-09-10
申请号：US12276637
申请日：2008-11-24
Applicant: Stanley D. Stearns
Inventor： Stanley D. Stearns
IPC: A61M5/00
Abstract: A syringe which disperses medicate across a zone in the body during apparent conventional operation. The improved syringe includes a barrel, a plunger, and an operating cylinder. In operation, the needle of the syringe is inserted into the body at the distal portion of the portion of the body which is to receive the medicate. A single arm is attached to the barrel and passes through an operating cylinder with a thumb rest on its top. As a result, in operation, the user draws the single arm up to the thumb rest, thus causing the syringe to withdraw during injection and leaving a patch of medicate during operation.
Abstract translation: 注射器，其在常规操作期间将药物分散在体内的区域中。 改进的注射器包括筒，柱塞和操作筒。 在操作中，将注射器的针插入身体中的待接受药物的身体部分的远端部分。 单个臂连接到枪管，并通过一个操作缸，拇指放在其顶部。 结果，在操作中，用户将单臂拉到拇指托架，从而使注射器在注射期间退出并在操作期间留下一片药物。
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3.发明申请Methods for Treatment of Tumors by Direct Administration of a Radioisotope 审中-公开通过直接施用放射性同位素治疗肿瘤的方法公开(公告)号：US20120251442A1
公开(公告)日：2012-10-04
申请号：US13469677
申请日：2012-05-11
Applicant: R. Keith Frank , Kenneth McMillan , Edna Sue McMillian , Jaime Simon , H. Max Loy, JR. , Stanley D. Stearns
Inventor： R. Keith Frank , Kenneth McMillan , Edna Sue McMillian , Jaime Simon , H. Max Loy, JR. , Stanley D. Stearns
CPC classification number: A61K51/1217
Abstract: This invention provides a safer and more effective treatment for non-intracavitary undesirable tissue masses, especially bone cancer and soft tissue tumors. The method involves the direct administration of a therapeutically-effective dose of a formulated radioisotope composition nearby or directly into the tissue mass. Small volumes of the composition are used.Administration of the dose for bone cancer may be done through a hole or multiple holes created in the bone using a miniature drill. Delivery of the dose directly into a tumor may be accomplished using a microsyringe or a miniature pump capable of accurately delivering microliter amounts of material.
Abstract translation: 本发明为非腔内不期望的组织块，特别是骨癌和软组织肿瘤提供更安全和更有效的治疗。 该方法包括在组织块中直接施用治疗有效剂量的配制的放射性同位素组合物或直接施用于组织块。 使用小体积的组合物。 可以通过使用微型钻头在骨头中产生的孔或多个孔来进行骨癌剂量的施用。 可以使用能够精确地递送微量的材料的微量注射器或微型泵来将剂量直接递送到肿瘤中。
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公开(公告)号：US20180028754A1
公开(公告)日：2018-02-01
申请号：US15718888
申请日：2017-09-28
Applicant: Gabriel Institute, Inc.
Inventor： Stanley D. Stearns , H. Max Loy, JR. , Donald G. Davis
CPC classification number: A61M5/284 , A61M5/16886 , A61M5/172 , A61M5/1785 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
Abstract: A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.
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公开(公告)号：US09022987B2
公开(公告)日：2015-05-05
申请号：US13298742
申请日：2011-11-17
Applicant: Stanley D. Stearns , H. Max Loy, Jr. , Donald G. Davis
Inventor： Stanley D. Stearns , H. Max Loy, Jr. , Donald G. Davis
CPC classification number: A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
Abstract: A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.
Abstract translation: 一种分配装置，其通过针将药物分散在身体内的区域内，零压差。 该装置包括在使用期间被封装在管状针接收构件内的针，与针流体连通的治疗剂储存器，定位在所述壳体内，并与针连通，第二储存器，储存器 与治疗剂储存器连通的连接管道，与第二储存器中的流体连通并与所述储存器连接管道连通的流体驱动器，以及附接到所述针头或所述针头接收构件的线性驱动器。
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Patent Agency Ranking
公开(公告)号：US08251999B2
公开(公告)日：2012-08-28
申请号：US12437910
申请日：2009-05-08
Applicant: Stanley D. Stearns , H. Max Loy, Jr.
Inventor： Stanley D. Stearns , H. Max Loy, Jr.
IPC: A61B17/00
CPC classification number: A61B17/1642 , A61B17/3472 , A61B2017/003 , Y10T408/568 , Y10T408/665
Abstract: A minimally invasive and particularly small system for drilling into bone) and for providing for delivery of medical treatment is provided. The drilling system includes a miniature shaft, a bit, a guide tube encapsulating the shaft during drilling and a capillary tube thereafter, a capillary tube, and a stylet. As a result, a hole, targeted towards a cancerous lesion within the bone, is possible. After removal of the shaft, the treatment may be introduced via the capillary tube after removal of the stylet.
Abstract translation: 提供了一种用于钻入骨骼的微创特别小的系统，并且用于提供医疗处理。 钻井系统包括微型轴，钻头，在钻孔期间封装轴的导管和其后的毛细管，毛细管和探针。 因此，可以有一个针对骨内癌变病变的孔。 除去轴之后，可以在去除探针后通过毛细管引入治疗。
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公开(公告)号：US20150224260A1
公开(公告)日：2015-08-13
申请号：US14679756
申请日：2015-04-06
Applicant: Gabriel Institute, Inc.
Inventor： Stanley D. Stearns , H. Max Loy, JR. , Donald G. Davis
CPC classification number: A61M5/284 , A61M5/16886 , A61M5/172 , A61M5/1785 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
Abstract: A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.
Abstract translation: 分配装置，其通过针将药物分散在身体内的区域上。 该装置包括在使用期间被封装在管状针接收构件内的针，与针流体连通的储存器，定位在壳体内并与针连通，第二储存器，储存器连接 与储存器连通的导管，与第二储存器中的流体连通并与储存器连接导管连通的流体驱动器，以及附接到针或针接收构件的线性驱动器。 流体驱动器将流体从第二储存器推动到储存器连接导管，从而在针朝向壳体的线性位移期间将储存器驱动治疗剂。 在线性驱动器的操作期间，通过管道维持从治疗剂储存器到针的流体连通。
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公开(公告)号：US20120065618A1
公开(公告)日：2012-03-15
申请号：US13298742
申请日：2011-11-17
Applicant: Stanley D. Stearns , H. Max Loy, JR. , Donald G. Davis
Inventor： Stanley D. Stearns , H. Max Loy, JR. , Donald G. Davis
IPC: A61M5/31
CPC classification number: A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
Abstract: A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.
Abstract translation: 一种分配装置，其通过针将药物分散在身体内的区域内，零压差。 该装置包括在使用期间被封装在管状针接收构件内的针，与针流体连通的治疗剂储存器，定位在所述壳体内，并与针连通，第二储存器，储存器 与治疗剂储存器连通的连接管道，与第二储存器中的流体连通并与所述储存器连接管道连通的流体驱动器，以及附接到所述针头或所述针头接收构件的线性驱动器。
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公开(公告)号：US08900234B2
公开(公告)日：2014-12-02
申请号：US13528418
申请日：2012-06-20
Applicant: Stanley D. Stearns , H. Max Loy, Jr.
Inventor： Stanley D. Stearns , H. Max Loy, Jr.
CPC classification number: A61B17/1642 , A61B17/3472 , A61B2017/003 , Y10T408/568 , Y10T408/665
Abstract: A minimally invasive method for drilling into bone and for providing for delivery of medical treatment is provided. The method includes use of a drilling system includes a miniature shaft, a bit, a guide tube encapsulating the shaft during drilling and a cortex adapter thereafter to prevent closure of the drilled hole, a stylet to prevent blockage of the resulting passage, and introduction for treatment following removal of the stylet. As a result, a hole, targeted towards a cancerous lesion within the bone, is possible.
Abstract translation: 提供了一种用于钻入骨骼并用于提供医疗处理的微创方法。 该方法包括使用钻孔系统，其包括微型轴，钻头，在钻孔期间封装轴的引导管以及之后的皮质适配器，以防止钻孔闭合，探针以防止堵塞所产生的通道，并引入 去除探针后进行治疗。 因此，可以有一个针对骨内癌变病变的孔。
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10.发明申请Compositions and methods for treatment of tumors by direct administration of a radioisotope 审中-公开通过直接施用放射性同位素治疗肿瘤的组合物和方法公开(公告)号：US20100196268A1
公开(公告)日：2010-08-05
申请号：US12798473
申请日：2010-04-05
Applicant: R. Keith Frank , Kenneth McMillan , Jaime Simon , H.Max Loy, JR. , Stanley D. Stearns , Edna Sue McMillan
Inventor： R. Keith Frank , Kenneth McMillan , Jaime Simon , H.Max Loy, JR. , Stanley D. Stearns , Edna Sue McMillan
CPC classification number: A61K51/1217
Abstract: This invention provides a safer and more effective treatment for non-intracavitary undesirable tissue masses, especially bone cancer and soft tissue tumors. The method involves the direct administration of a therapeutically-effective dose of a formulated radioisotope composition nearby or directly into the tissue mass. Small volumes of the composition are used.Administration of the dose for bone cancer may be done through a hole or multiple holes created in the bone using a miniature drill. Delivery of the dose directly into a tumor may be accomplished using a microsyringe or a miniature pump capable of accurately delivering microliter amounts of material.
Abstract translation: 本发明为非腔内不期望的组织块，特别是骨癌和软组织肿瘤提供更安全和更有效的治疗。 该方法包括在组织块中直接施用治疗有效剂量的配制的放射性同位素组合物或直接施用于组织块。 使用小体积的组合物。 可以通过使用微型钻头在骨头中产生的孔或多个孔来进行骨癌剂量的施用。 可以使用能够精确地递送微量的材料的微量注射器或微型泵来将剂量直接递送到肿瘤中。
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