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81.发明授权公开(公告)号：US09280639B2
公开(公告)日：2016-03-08
申请号：US14621199
申请日：2015-02-12
申请人： HeartFlow, Inc.
发明人： Sethuraman Sankaran , Charles A. Taylor , Gilwoo Choi , Michiel Schaap , Christopher K. Zarins , Leo J. Grady
CPC分类号： A61B34/10 , A61B5/02007 , A61B5/02028 , A61B5/026 , A61B5/7275 , A61B6/032 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B2034/105 , G06F17/50 , G06F17/5009 , G06F19/00 , G06F19/26 , G06F19/325 , G06T7/0012 , G06T2207/30096 , G06T2207/30101 , G16H50/20 , G16H50/30 , G16H50/50
摘要： Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of a location of disease in the patient's vasculature based on the received patient-specific data; identifying one or more changes in geometry of the anatomic model based on a modeled progression or regression of disease at the location; calculating one or more values of a blood flow characteristic within the patient's vasculature using a computational model based on the identified one or more changes in geometry of the anatomic model; and generating an electronic graphical display of a relationship between the one or more values of the calculated blood flow characteristic and the identified one or more changes in geometry of the anatomic model.
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82.发明授权公开(公告)号：US09239905B1
公开(公告)日：2016-01-19
申请号：US14621129
申请日：2015-02-12
申请人： HeartFlow, Inc.
发明人： Sethuraman Sankaran , Charles A. Taylor , Gilwoo Choi , Michiel Schaap , Christopher K. Zarins , Leo J. Grady
CPC分类号： A61B34/10 , A61B5/02007 , A61B5/02028 , A61B5/026 , A61B5/7275 , A61B6/032 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B2034/105 , G06F17/50 , G06F17/5009 , G06F19/00 , G06F19/26 , G06F19/325 , G06T7/0012 , G06T2207/30096 , G06T2207/30101 , G16H50/20 , G16H50/30 , G16H50/50
摘要： Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of a location of disease in the patient's vasculature based on the received patient-specific data; identifying one or more changes in geometry of the anatomic model based on a modeled progression or regression of disease at the location; calculating one or more values of a blood flow characteristic within the patient's vasculature using a computational model based on the identified one or more changes in geometry of the anatomic model; and generating an electronic graphical display of a relationship between the one or more values of the calculated blood flow characteristic and the identified one or more changes in geometry of the anatomic model.
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83.发明授权公开(公告)号：US09220418B2
公开(公告)日：2015-12-29
申请号：US14254481
申请日：2014-04-16
申请人： HeartFlow, Inc.
发明人： Gilwoo Choi , Leo Grady , Michiel Schaap , Charles A. Taylor
IPC分类号： A61B5/02 , A61B5/026 , A61B5/055 , A61B5/00 , A61B6/03 , A61B8/12 , A61B6/00 , G06T7/00 , G06T7/60 , G06F19/00
CPC分类号： A61B34/10 , A61B5/0066 , A61B5/02007 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B6/032 , A61B6/503 , A61B6/504 , A61B6/5217 , A61B8/12 , G06F19/00 , G06T7/0012 , G06T2207/10104 , G06T2207/10108 , G06T2207/30104 , G16H50/30 , G16H50/50 , Y02A90/26
摘要： Systems and methods are disclosed for predicting coronary plaque vulnerability, using a computer system. One method includes acquiring anatomical image data of at least part of the patient's vascular system; performing, using a processor, one or more image characteristics analysis, geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis on the anatomical image data; predicting, using the processor, a coronary plaque vulnerability present in the patient's vascular system, wherein predicting the coronary plaque vulnerability includes calculating an adverse plaque characteristic based on results of the one or more of image characteristics analysis, geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis of the anatomical image data; and reporting, using the processor, the calculated adverse plaque characteristic.
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84.发明授权Systems and methods for data and model-driven image reconstruction and enhancement 有权用于数据和模型驱动的图像重建和增强的系统和方法公开(公告)号：US09070214B1
公开(公告)日：2015-06-30
申请号：US14310746
申请日：2014-06-20
申请人： HeartFlow, Inc.
发明人： Leo Grady , Michiel Schaap
CPC分类号： G06T11/003 , A61B6/5205 , G06K9/46 , G06K9/6201 , G06K2009/4666 , G06T5/001 , G06T5/50 , G06T7/0012 , G06T7/0014 , G06T11/005 , G06T11/006 , G06T2207/10072 , G06T2207/20081 , G06T2207/30004 , G06T2207/30101 , G06T2211/404 , G06T2211/424 , G06T2211/436
摘要： Systems and methods are disclosed for image reconstruction and enhancement, using a computer system. One method includes acquiring a plurality of images associated with a target anatomy; determining, using a processor, one or more associations between subdivisions of localized anatomy of the target anatomy identified from the plurality of images, and local image regions identified from the plurality of images; performing an initial image reconstruction based on image acquisition information of the target anatomy; and updating the initial image reconstruction or generating a new image reconstruction based on the image acquisition information and the one or more determined associations.
摘要翻译： 公开了使用计算机系统的图像重建和增强的系统和方法。 一种方法包括获取与目标解剖结构相关联的多个图像; 使用处理器确定从多个图像识别的目标解剖结构的局部解剖结构的细分之间的一个或多个关联以及从多个图像识别的局部图像区域; 基于目标解剖结构的图像获取信息执行初始图像重建; 以及基于所述图像获取信息和所述一个或多个确定的关联来更新所述初始图像重建或生成新的图像重建。
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85.发明授权Systems and methods for correction of artificial deformation in anatomic modeling 有权解剖建模中人造变形矫正的系统和方法公开(公告)号：US08958623B1
公开(公告)日：2015-02-17
申请号：US14311605
申请日：2014-06-23
申请人： HeartFlow, Inc.
发明人： Leo John Grady , Michiel Schaap , Sophie Khem , Sarah Wilkes , Ying Bai
CPC分类号： A61B34/10 , A61B6/5258 , A61B2034/105 , G06F17/5009 , G06F19/00 , G06F19/12 , G06K9/6215 , G06K9/6267 , G06T7/0012 , G06T7/60 , G06T7/70 , G06T13/20 , G06T2207/10004 , G06T2207/30101 , G06T2207/30104 , G09B9/00 , G09B23/303 , G16H50/50
摘要： Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
摘要翻译： 公开了用于校正解剖建模中的人造变形的系统和方法。 一种方法包括获得解剖模型; 获取指示所述解剖模型的人造变形的存在的信息; 识别与人造变形相关联的解剖模型的一部分; 估计对应于解剖模型部分的非变形局部区域; 以及基于估计的非变形局部区域来修改与人造变形相关联的解剖模型的部分。
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公开(公告)号：US08831315B1
公开(公告)日：2014-09-09
申请号：US14172594
申请日：2014-02-04
申请人： HeartFlow, Inc.
发明人： Timothy A. Fonte , Leo J. Grady , Zhongle Wu , Michiel Schaap , Stanley C. Hunley , Souma Sengupta
CPC分类号： G06T7/0012 , A61B5/026 , A61B5/0261 , A61B5/0263 , A61B6/032 , A61B6/037 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B6/5258 , A61B6/5294 , A61B8/0883 , A61B8/5223 , A61B2576/02 , G01R33/5635 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/10132 , G06T2207/30004 , G06T2207/30104 , G06T2207/30168 , G06T2207/30172 , G06T2207/30196 , G06T2210/41 , G16H50/50
摘要： Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
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