公开(公告)号：US11278230B2

公开(公告)日：2022-03-22

申请号：US16513469

申请日：2019-07-16

申请人： McMaster University

发明人： John Francis Connolly ,  Kyle Ingram Ruiter ,  Rober Boshra

IPC分类号： A61B5/377 ,  A61B5/291 ,  A61B5/16 ,  G06N20/00 ,  A61B5/316 ,  G06N3/08 ,  A61B5/00 ,  A61B5/30

摘要： An improved system for assessing cognitive function is described that uses tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, which, for example, can be encapsulated as a data structure. The data sets can include tracked specific response types, at different times and amplitudes, including, but not limited to, event related potential signal components. Brainwave features including, event related potentials, are tracked in relation to both pre-attentive brain responses and consciously controlled attention responses.

公开(公告)号：US11253701B2

公开(公告)日：2022-02-22

申请号：US17463606

申请日：2021-09-01

申请人： Evoke Neuroscience, Inc.

发明人： David W Hagedorn

IPC分类号： A61N1/00 ,  A61N1/36 ,  A61B5/00 ,  A61N2/00 ,  A61N1/372 ,  A61N2/02 ,  A61B5/291 ,  A61B5/375 ,  A61B5/377 ,  A61N1/04

摘要： The present method and system provides a neuromodulation therapy including receiving a plurality of input data relating to a patient, the input data including brain value measurements and body value measurements. The method and system includes analyzing the input data in reference to reference data generated based on machine learning operations associated with existing patient data and reference database data. Based thereon, the method and system includes electronically determining, a brain malady and a severity value for the patient and electronically generating a treatment protocol for the patient, the treatment protocol includes transcranial stimulation parameters. Therein, the method and system includes applying a transcranial stimulation using the transcranial stimulation parameters based on the treatment protocol.

公开(公告)号：US11250447B2

公开(公告)日：2022-02-15

申请号：US16790164

申请日：2020-02-13

申请人： The Nielsen Company (US), LLC

发明人： Hans C. Lee ,  Timmie T. Hong ,  Juan C. Munoz

IPC分类号： A61B5/00 ,  G06Q30/02 ,  A61B5/0205 ,  A61B5/16 ,  H04N7/16 ,  H04N21/258 ,  H04N21/422 ,  H04N21/442 ,  H04N21/475 ,  A61B5/377 ,  A61B5/11 ,  H04H60/33

摘要： An example system includes a first headset including first sensor to gather first user data from a first subject during exposure to media, the first user data including at least one of psychophysiological data or physiological data; and a first processor to generate first data indicative of an emotional response of the first subject based on the first user data. The example system includes a second headset including a second sensor to gather second user data from the second subject during exposure to the media, the second user data including at least one of psychophysiological data or physiological data; a second processor to generate second data indicative of an emotional response of the second subject based on the second user data and synchronize the second data with the first data to generate synchronized response data; and a second transmitter to transmit the synchronized response data to a central processor.

公开(公告)号：US11241185B2

公开(公告)日：2022-02-08

申请号：US16286220

申请日：2019-02-26

申请人： Korea University Research and Business Foundation

发明人： Byoung-Kyong Min

IPC分类号： A61B5/048 ,  A61N1/04 ,  A61N1/36 ,  A61B5/00 ,  A61B5/0478 ,  A61B5/374 ,  A61B5/291 ,  A61M21/00 ,  A61B5/377

摘要： Provided is a method for enhancing cognitive function based on individual cognitive frequency resonance that intentionally and selectively enhances a specific cognitive function by resonating with brain waves through brain stimulation using an electric current of the same frequency or waveform as individual cognitive frequency generated during a cognitive task, and the method includes executing, by a subject, a cognitive task.

公开(公告)号：US20210393955A1

公开(公告)日：2021-12-23

申请号：US17463606

申请日：2021-09-01

申请人： Evoke Neuroscience, Inc.

发明人： David W. Hagedorn

IPC分类号： A61N1/36 ,  A61B5/00 ,  A61N2/00 ,  A61N1/372 ,  A61N2/02 ,  A61B5/291 ,  A61B5/375 ,  A61B5/377

摘要： The present method and system provides a neuromodulation therapy including receiving a plurality of input data relating to a patient, the input data including brain value measurements and body value measurements. The method and system includes analyzing the input data in reference to reference data generated based on machine learning operations associated with existing patient data and reference database data. Based thereon, the method and system includes electronically determining, a brain malady and a severity value for the patient and electronically generating a treatment protocol for the patient, the treatment protocol includes transcranial stimulation parameters. Therein, the method and system includes applying a transcranial stimulation using the transcranial stimulation parameters based on the treatment protocol.

公开(公告)号：US11185711B2

公开(公告)日：2021-11-30

申请号：US16099944

申请日：2017-05-11

申请人： S.I.S.T.E.M.I. S.R.L.—SOCIETA′ ITALIANA SEQEX TECNOLOGIE ELETTRO MEDICALI INNOVATIVE

发明人： Valerio Dallago

IPC分类号： A61N2/02 ,  A61M21/00 ,  A61N2/00 ,  A61B5/0205 ,  A61B5/00 ,  G16H20/30 ,  A61B5/024 ,  A61B5/053 ,  A61B5/08 ,  A61B5/318 ,  A61B5/369 ,  A61B5/377

摘要： A device for treatments on the human body with variable magnetic fields, which is provided with:
at least one electric waveform generator to be connected to at least one Helmholtz coil to be brought close to the person or persons to be treated and producing variable low-intensity and low-frequency magnetic fields. The device further includes
at least one impedance meters with electrode terminals to be applied to the person in order to assess the effectiveness of the waves of the generator; and
at least one electronic processing unit for the management of the waveform generator or generators as a function of the measurements of the impedance meter and of memory parameters stored in the processing unit.

公开(公告)号：US11179091B2

公开(公告)日：2021-11-23

申请号：US16311526

申请日：2017-06-23

申请人： Saluda Medical Pty Ltd

发明人： Dean Michael Karantonis ,  Peter Scott Vallack Single ,  Kai Huang

IPC分类号： A61B5/377 ,  A61N1/36 ,  A61B5/24 ,  A61B5/00 ,  A61B5/05 ,  A61N1/378 ,  A61N1/18 ,  A61N1/372 ,  A61B5/291

摘要： A neural stimulus comprises at least three stimulus components, each comprising at least one of a temporal stimulus phase and a spatial stimulus pole. A first stimulus component delivers a first charge which is unequal to a third charge delivered by a third stimulus component, and the first charge and third charge are selected so as to give rise to reduced artefact at recording electrodes. In turn this may be exploited to independently control a correlation delay of a vector detector and an artefact vector to be non-parallel or orthogonal.

公开(公告)号：US20210353224A1

公开(公告)日：2021-11-18

申请号：US17282624

申请日：2019-10-15

申请人： The Board of Trustees of the Leland Stanford Junior University ,  Board of Regents, The University of Texas System

发明人： Amit Etkin ,  Madhukar Trivedi ,  Wei Wu

IPC分类号： A61B5/00 ,  A61B5/374 ,  A61B5/377 ,  A61B5/245 ,  A61B5/16 ,  G16H50/70 ,  G16H50/20 ,  G16H40/67 ,  G16H30/20 ,  G16H30/40 ,  G06N20/00 ,  G01R33/48

摘要： Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.

公开(公告)号：US11154234B2

公开(公告)日：2021-10-26

申请号：US15707190

申请日：2017-09-18

申请人： CYREBRO TECHNOLOGIES

发明人： Quentin Barthelemy ,  Louis Mayaud

IPC分类号： A61B5/0482 ,  A61B5/375 ,  G16H50/20 ,  G16H20/10 ,  G16H20/40 ,  A61B5/316 ,  A61B5/374 ,  A61B5/377 ,  A61B5/00

摘要： The present invention relates to a computer-implemented method for modifying nociception in a subject using electroencephalographic data acquired from the brain of a subject, the method comprising the steps of: receiving electroencephalographic data comprising at least two electroencephalographic signals measured simultaneously from at least two electroencephalogram channels, computing a Fourier transform of the at least two electroencephalographic signals on a temporal window; averaging complex Fourier coefficients in the frequency band of alpha waves; computing an alpha phase concentration neuromarker on consecutive epochs of the electroencephalographic data, generating a sensorial stimulus representing alpha phase concentration neuromarker using an output generator. The present invention also relates to a method for training a subject to reinforce self-modulation of pain pathways.

公开(公告)号：US11141093B2

公开(公告)日：2021-10-12

申请号：US16191596

申请日：2018-11-15

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Gary Nelson Garcia Molina ,  David White ,  Birpal Singh Sachdev ,  William Gaussa

IPC分类号： A61B5/377 ,  A61M21/02 ,  A61B5/369 ,  A61N5/06 ,  A61B5/00 ,  A61M21/00 ,  A61N2/00

摘要： The present disclosure pertains to a system configured to deliver sensory stimulation to a user to enhance a target cognitive domain during a sleep session. Example target cognitive domains include memory consolidation, vigilance, verbal fluency, sleepiness, and/or other target cognitive domains. The stimulation is adjusted based on the target cognitive domain to be enhanced. Responsive to one or more brain activity parameters indicating the user is in sufficiently deep sleep, the system is configured to cause one or more sensory stimulators to provide sensory stimulation to the user according to a stimulation strategy associated with the target cognitive domain. The system is configured to determine the effect of the sensory stimulation provided to the user using a quantification method associated with the stimulation strategy and the target cognitive domain. The system includes one or more sensory stimulators, one or more sensors, one or more hardware processors, and/or other components.