公开(公告)号：US20240206731A1

公开(公告)日：2024-06-27

申请号：US18511832

申请日：2023-11-16

Applicant: Ablacon Inc.

Inventor： Peter Ruppersberg

IPC: A61B5/00 ,  A61B5/287 ,  A61B5/316 ,  A61B5/327 ,  A61B5/339 ,  A61B5/341 ,  A61B18/00 ,  A61B18/14 ,  A61B90/00

CPC classification number: A61B5/0006 ,  A61B5/287 ,  A61B5/316 ,  A61B5/327 ,  A61B5/339 ,  A61B5/341 ,  A61B5/6852 ,  A61B5/6858 ,  A61B5/742 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/1467 ,  A61B2090/065

Abstract: Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each of selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.

公开(公告)号：US11918381B2

公开(公告)日：2024-03-05

申请号：US17855440

申请日：2022-06-30

Applicant: Apple Inc.

Inventor： Shahrooz Shahparnia ,  Erno H. Klaassen

IPC: A61B5/01 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/053 ,  A61B5/113 ,  A61B5/282 ,  A61B5/327 ,  A61B5/08 ,  A61B5/103 ,  A61B5/11

CPC classification number: A61B5/6892 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02444 ,  A61B5/053 ,  A61B5/113 ,  A61B5/282 ,  A61B5/327 ,  A61B5/4815 ,  A61B5/7278 ,  A61B5/02405 ,  A61B5/02438 ,  A61B5/0816 ,  A61B5/1036 ,  A61B5/1102 ,  A61B5/1126 ,  A61B5/6843 ,  A61B2560/0242 ,  A61B2560/0252 ,  A61B2562/0214 ,  A61B2562/0247 ,  A61B2562/046

Abstract: This relates to a monitoring system capable of measuring a plurality of vital signs. The monitoring system can include a plurality of sensors including, but not limited to, electrodes, piezoelectric sensors, temperature sensors, and accelerometers. The monitoring system can be capable of operating in one or more operation modes such as, for example: capacitance measurement mode, electrical measurement mode, piezoelectric measurement mode, temperature measurement mode, acceleration measurement mode, impedance measurement mode, and standby mode. Based on the measured values, the monitoring system can analyze the user's sleep, provide feedback and suggestions to the user, and/or can adjust or control the environmental conditions to improve the user's sleep. The monitoring system can further be capable of analyzing the sleep of the user(s) without directly contacting or attaching uncomfortable probes to the user(s) and without having to analyze the sleep in an unknown environment (e.g., a medical facility).

公开(公告)号：US20230363655A1

公开(公告)日：2023-11-16

申请号：US18029260

申请日：2021-09-30

Applicant: Queen's University at Kingston

Inventor： Pritam Sarkar ,  Ali Etemad

IPC: A61B5/024 ,  A61B5/327 ,  A61B5/00 ,  G06N3/08

CPC classification number: A61B5/02416 ,  A61B5/327 ,  A61B5/7267 ,  G06N3/08

Abstract: Electrocardiogram (ECG) is the electrical measurement of cardiac activity, whereas photoplethysmogram (PPG) is the optical measurement of volumetric changes in blood circulation. While both signals are used for heart rate monitoring, from a medical perspective, ECG is more useful as it carries additional cardiac information. For continuous cardiac monitoring, PPG sensors are practical. Methods for generating an ECG from a PPG signal may include subjecting the PPG signal to a deep learning network trained to generate a corresponding ECG. The deep learning network may include an adversarial model such as a generative adversarial network (GAN) that may use an attention-based generator to learn local salient features, and may also use dual discriminators to preserve the integrity of generated data in both time and frequency domains

公开(公告)号：US20230284959A1

公开(公告)日：2023-09-14

申请号：US18111941

申请日：2023-02-21

Applicant: XSPLINE S.P.A.

Inventor： Sviatoslav KHAMZIN ,  Michail CHMELEVSKY ,  Werner RAINER

IPC: A61B5/341 ,  A61B5/35 ,  A61B5/327 ,  A61B5/343 ,  G06N3/08

CPC classification number: A61B5/341 ,  A61B5/35 ,  A61B5/327 ,  A61B5/343 ,  G06N3/08

Abstract: Method for generating an activation map indicative of a time propagation of an action potential wavefront in a heart of a patient, the method being executed by a control unit and comprising the steps of: acquiring measured electrocardiography, ECG, data of the patient; generating, based on white noise, at least one set of identification parameters, each set of identification parameters identifying respective random ECG data and a respective random activation map that is indicative of a respective time propagation of a random action potential wavefront in the heart of the patient; generating, based on each set of identification parameters, said respective random ECG data; comparing the random ECG data and the measured ECG data to determine if there is correspondence between them; and if there is correspondence between the random ECG data and the measured ECG data, generating the activation map based on the at least one random activation map determined based on the at least one set of identification parameters used to obtain the random ECG data in correspondence with the measured ECG data.

公开(公告)号：US20230263448A1

公开(公告)日：2023-08-24

申请号：US18161641

申请日：2023-01-30

Applicant: AliveCor, Inc.

Inventor： Sean Cohen ,  Siva Somayajula ,  David E. Albert

IPC: A61B5/282 ,  A61B5/339 ,  A61B5/327 ,  A61B5/00 ,  A61B5/346 ,  A61B90/96

CPC classification number: A61B5/282 ,  A61B5/339 ,  A61B5/327 ,  A61B5/0006 ,  A61B5/346 ,  A61B90/96

Abstract: Described herein is an apparatus for monitoring various physiological parameters of a user. The apparatus may include a housing with a small or reduced form factor near the size of a credit or debit card, so as to allow a user to obtain e.g., an electrocardiogram (ECG) measurement from various locations. The apparatus may include an electrode assembly comprising a set of electrodes disposed on the housing to perform an ECG by sensing an electrical signal corresponding to heart activity of a user when in contact with skin of the user and output the electrical signal. The apparatus may detect or generate six or more ECG leads.

公开(公告)号：US11547340B2

公开(公告)日：2023-01-10

申请号：US16499539

申请日：2018-03-20

Applicant: THE UNIVERSITY OF TOKYO

Inventor： Ichiro Sakuma ,  Naoki Tomii ,  Hiroshi Seno ,  Haruo Honjo ,  Masatoshi Yamazaki

IPC: A61B5/327 ,  G16H30/40

Abstract: An aspect of the present disclosure calculates a phase variance value indicating a degree of variance of a phase in a surrounding of each position in a biological tissue, based on phase values of excitation wave at respective positions in the biological tissue that acts in response to excitation caused by propagation of the excitation wave in the tissue, and generates an analysis map, based on a time series of at least part of the phase variance values at the respective positions. Since the phase variance value indicates the degree of variance of the phase in the surrounding, a position having a large degree of variance of the phase in the surrounding may be specified as a rotation center of rotating excitation wave.

公开(公告)号：US20220338783A1

公开(公告)日：2022-10-27

申请号：US17235986

申请日：2021-04-21

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.

Inventor： Yair Palti ,  Israel Zilberman ,  Assaf Govari ,  Vadim Gliner ,  Andres Claudio Altmann ,  Gili Attias

IPC: A61B5/367 ,  A61B5/327 ,  A61B5/287 ,  A61B5/343

Abstract: A method includes receiving a plurality of data points including electrophysiological (EP) values measured at respective positions in at least a portion of an organ of a patient. Some of the EP values are classified as outlier values in accordance with a defined criterion. A visual representation of at least the portion of the organ is derived from the plurality of data points. The visual representation represents the EP values with respective colors, and visualizes less than all the outlier values, by performing one or both of (a) identifying outlier values that deviate from respective neighboring EP values by less than a defined deviation, and representing the outlier values using colors that match the neighboring EP values, and (b) setting for the visual representation a mapping, which maps the EP values to the colors and which excludes at least some of the outlier values.

公开(公告)号：US11445963B1

公开(公告)日：2022-09-20

申请号：US17494806

申请日：2021-10-05

Applicant: HeartBeam, Inc.

Inventor： Petra Belicev ,  Bosko Bojovic ,  Ljupco Hadzievski ,  Branislav Vajdic ,  Vladimir Atanasoski ,  Goran Gligoric ,  Marjan Miletic

IPC: A61B5/327 ,  A61B5/332 ,  A61B5/28 ,  A61B5/00 ,  A61B5/339

Abstract: Systems and apparatus for synthesizing (generating) 12-lead ECG dataset from 3-lead ECG data. In particular, one or more transformation parameters may be determined that may be applied to 3-lead ECG dataset to generate 12-lead ECG data with particular speed and accuracy. The transformation parameters, which may include a plurality of matrices, may be determined from a synchronized patient's 12-lead ECG dataset and 3-lead ECG data. The 12-lead ECG dataset may be collected at a different time than the 3-lead ECG data. In some embodiments, the 12-lead ECG dataset and/or the 3-lead ECG dataset may be resampled prior to determining the transformation parameters.

公开(公告)号：US11344244B2

公开(公告)日：2022-05-31

申请号：US17277266

申请日：2019-09-06

Applicant: AliveCor, Inc.

Inventor： David E. Albert

IPC: A61B5/327 ,  A61B5/28 ,  A61B5/00

Abstract: Described herein are devices, systems, and methods for sensing and generating a one or more of the 12 leads of a standard ECG with a mobile computing device. In some embodiments, three electrodes are positioned on a mobile computing device so that an individual may comfortably contact all three sensors at once to generate a six lead ECG which may be displayed on a display of said mobile computing device. In some embodiments, analysis carried out further comprises determining a QRS axis and QRST angle.

公开(公告)号：US11337616B2

公开(公告)日：2022-05-24

申请号：US16577425

申请日：2019-09-20

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Limei Cheng ,  Eric Thomas Carlson ,  Srinivasan Vairavan ,  Minnan Xu

IPC: A61B5/02 ,  A61B5/024 ,  A61B5/0255 ,  A61B5/00 ,  A61B5/316 ,  A61B5/344 ,  A61B5/352 ,  A61B5/366 ,  A61B5/327 ,  A61B5/364

Abstract: System (10) for extracting a fetal heart rate from at least one maternal signal using a computer processor (26). The system includes sensors (12-18) attached to a patient to receive abdominal ECG signals and a recorder and digitizer (20) to record and digitize each at least one maternal signal in a maternal signal buffer (22A-22D). The system further includes a peak detector (40) to identify candidate peaks in the maternal signal buffer. The signal stacker (42) of the system stacks the divides at least one maternal signal buffer into a plurality of snippets, each snippet including one candidate peak and a spatial filter (44) to identify and attenuate a maternal QRS signal in the plurality of snippets of the maternal signal buffer, the spatial filter including at least one of principal component analysis and orthogonal projection, to produce a raw fetal ECG signal which is stored in a raw fetal ECG buffer. The system further includes a fetal QRS identifier (46) for identifying peaks in the raw fetal ECG buffer by at least one of principal component analysis and a peak-detector followed by rule based fQRS extraction and a merger (48) to calculate and merge the fetal heart rate from the identified peaks.