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公开(公告)号：US20240346670A1
公开(公告)日：2024-10-17
申请号：US18292188
申请日：2022-07-06
Applicant: LightLab Imaging, Inc.
Inventor： Shimin Li , Ajay Gopinath
CPC classification number: G06T7/33 , G06T7/0012 , G06T2207/30101
Abstract: The present disclosure provides systems and methods for automatically aligning intravascular data taken during a plurality of pullbacks in a target blood vessel. Extraluminal images may be taken to determine the location of the guide catheter in the target vessel. Two or more pullbacks may then be performed in the target vessel. The start and end point of each pullback may be determined. A distance between the end point of each pullback and the proximal tip, or junction point, of the guide catheter may be determined. A difference between the end point of each pullback and the junction point may be determined. The difference between the distances from the end of the pullback and the junction point may correspond to the distance to offset one of the representations of the pullbacks in order to automatically align the representation of the pullbacks.
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公开(公告)号：US20240202913A1
公开(公告)日：2024-06-20
申请号：US18287252
申请日：2022-04-22
Applicant: LightLab Imaging, Inc.
Inventor： Timothy Preston Connelly , Christopher Erik Griffin , Shimin Li
CPC classification number: G06T7/0012 , A61B5/02007 , G06T5/20 , G06T5/50 , G06T5/70 , G06T7/11 , G06T7/13 , G06T7/66 , G06T2207/30101
Abstract: Methods, systems, and apparatus, including computer-readable storage media for calculating lumen-centered calcium arcs. A method includes receiving, by one or more processors, an image frame and an identification of a region of plaque in the image frame. The image frame is taken while the imaging device is in a lumen depicted in the image frame. The one or more processors identify a lumen-center of the lumen in the image frame, and generate a lumen-centered are having a coverage angle centered on the lumen-center, using at least the lumen-center.
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公开(公告)号：US20240163404A1
公开(公告)日：2024-05-16
申请号：US18388425
申请日：2023-11-09
Applicant: LightLab Imaging, Inc.
Inventor： Tomas Russ , Steven M. Stromski , Samir Farah , Mark Hoeveler , Douglas Tatosian
Abstract: The disclosure relates to a modular data acquisition and processing system for obtaining intravascular data, such as image data, for a patient. The modular system includes acquisition components in a patient procedure environment in communication with a processing engine in a remote environment. The remote processing engine may be used with different types of data acquisition systems. The modular system further includes a hub in the patient procedure environment, which maintain a persistent connection with the remote processing engine while enabling fast and reliable coupling to data acquisition components.
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公开(公告)号：US20240099585A1
公开(公告)日：2024-03-28
申请号：US18267670
申请日：2021-12-17
Applicant: LightLab Imaging, Inc.
Inventor： Justin Akira Blaber , Ajay Gopinath , Wei Chiu
CPC classification number: A61B5/0066 , A61B5/0261 , A61B5/1076
Abstract: The present disclosure provides systems and methods for determining a mean transit time of a bolus within the blood vessel by passing the bolus through the blood vessel while an intravascular imaging probe is held stationary. The probe may collect a plurality of image frames as the bolus passes the probe. The cross-sectional area of the bolus within the images frames may be determined by segmenting each image frame by thresholding, creating a vessel mask, and creating a contrast mask by applying an element-wise AND operator to the thresholded image and the vessel mask. The cross-sectional area of the bolus for the image frames may be plotted on an area dilution curve. Various fits may be applied to and various points may be identified on the area dilution curve. The various fits and points may be used to determine the mean transit time.
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75.发明公开公开(公告)号：US20230326032A1
公开(公告)日：2023-10-12
申请号：US18204493
申请日：2023-06-01
Applicant: LightLab Imaging, Inc.
Inventor： Shimin Li , Ajay Gopinath , Kyle Savidge
IPC: G06T7/11 , G06F18/40 , G06N3/04 , G06F18/214 , G06F18/211 , G06N3/08
CPC classification number: G06T7/11 , G06F18/40 , G06N3/04 , G06F18/214 , G06F18/211 , G06N3/08 , G06V2201/03
Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.
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Patent Agency Ranking
76.发明申请公开(公告)号：US20230075598A1
公开(公告)日：2023-03-09
申请号：US17980323
申请日：2022-11-03
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号：US20230005139A1
公开(公告)日：2023-01-05
申请号：US17854994
申请日：2022-06-30
Applicant: LightLab Imaging, Inc.
Inventor： Justin Akira Blaber , Ajay Gopinath , Gregory Patrick Amis , Kyle Savidge
Abstract: Aspects of the disclosure provide for methods, systems, and apparatuses, including computer-readable storage media, for lipid detection by identifying fibrotic caps in medical images of blood vessels. A method includes receiving one or more input images of a blood vessel and processing the one or more input images using a machine learning model trained to identify locations of fibrotic caps in blood vessels. The machine learning model is trained using a plurality of training images each annotated with locations of one or more fibrotic caps. A method includes identifying and characterizing fibrotic caps of lipid pools based on differences in radial signal intensities measured at different locations of an input image. A system can generate one or more output images having segments that are visually annotated representing predicted locations of fibrotic caps covering lipidic plaques.
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公开(公告)号：US11532087B2
公开(公告)日：2022-12-20
申请号：US17155778
申请日：2021-01-22
Applicant: LightLab Imaging, Inc.
Inventor： Sonal Ambwani , Christopher E. Griffin , James G. Peterson , Satish Kaveti , Joel M. Friedman
Abstract: The disclosure relates, in part, to computer-based visualization of stent position within a blood vessel. A stent can be visualized using intravascular data and subsequently displayed as stent struts or portions of a stent as a part of a one or more graphic user interface(s) (GUI). In one embodiment, the method includes steps to distinguish stented region(s) from background noise using an amalgamation of angular stent strut information for a given neighborhood of frames. The GUI can include views of a blood vessel generated using distance measurements and demarcating the actual stented region(s), which provides visualization of the stented region. The disclosure also relates to display of intravascular diagnostic information such as indicators. An indicator can be generated and displayed with images generated using an intravascular data collection system. The indicators can include one or more viewable graphical elements suitable for indicating diagnostic information such as stent information.
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公开(公告)号：US20220361847A1
公开(公告)日：2022-11-17
申请号：US17878564
申请日：2022-08-01
Applicant: LightLab Imaging, Inc.
Inventor： Christopher Hutchins , Michael Atlas , Terence Barnes
Abstract: In part, the invention relates to a probe suitable for use with image data collection system. The probe, in one embodiment, includes an optical transceiver, such as a beam director, and an acoustic transceiver such as an ultrasound transducer. The optical transceiver is in optical communication with an optical fiber in optical communication with a beam director configured to transmit light and receive scattered light from a sample such as a wall of a blood vessel. The acoustic transceiver includes an ultrasound device or subsystem such as a piezoelectric element configured to generate acoustic waves and receive reflected acoustic waves from the sample.
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公开(公告)号：US11461902B2
公开(公告)日：2022-10-04
申请号：US17084805
申请日：2020-10-30
Applicant: LightLab Imaging, Inc.
Inventor： Ajay Gopinath , Desmond Adler
IPC: A61B5/02 , A61B6/00 , G06T11/60 , G06T19/20 , G06T5/50 , G06T7/12 , G06T7/13 , A61B5/00 , A61B1/00
Abstract: In part, the disclosure relates to method for identifying regions of interest in a blood vessel. The method includes the steps of: providing OCT image data of the blood vessel; applying a plurality of different edge detection filters to the OCT image data to generate a filter response for each edge detection filter; identifying in each edge detection filter response any response maxima; combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered OCT data; and analyzing the edge filtered OCT data to identify a region of interest, the region of interest defined as a local cluster of response maxima. In one embodiment, one or more indicia are positioned in one or more panels to emphasize a reference vessel profile as part of a user interface.
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