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    Method of Protecting Wood Through Enhanced Penetration of Wood Preservatives and a Related Solution
    61.
    发明申请
    Method of Protecting Wood Through Enhanced Penetration of Wood Preservatives and a Related Solution 审中-公开
    通过木材防腐剂渗透保护木材的方法及相关解决方案

    公开(公告)号：US20090143334A1

    公开(公告)日：2009-06-04

    申请号：US12366131

    申请日：2009-02-05

    Applicant: Hans A. Ward ,  Cameron Scott

    Inventor： Hans A. Ward ,  Cameron Scott

    IPC: A01N25/00 ,  C09K3/00 ,  A01N47/10 ,  A01N41/10 ,  A01N43/64 ,  A61K31/425 ,  A01N31/08 ,  A01N33/12 ,  A01N65/00

    CPC classification number: C11C3/003 ,  A01N33/12 ,  A01N43/80 ,  A01N47/12 ,  A01N51/00 ,  A01N59/14 ,  C07C67/333 ,  C10G3/00 ,  C10G27/04 ,  C10G2300/1011 ,  Y02P30/20 ,  C07C69/52 ,  C07C69/533 ,  A01N25/30 ,  A01N2300/00 ,  A01N53/00

    Abstract: A method of protecting wood through enhanced penetration of wood preservatives includes providing a solution including (a) at least one amine oxide. (b) at least one organic wood preservative and (c) a buffering agent. The solution preferably has a pH of about 7 to 10. The solution is applied to the surface of the wood after which, with or without intervening storage, the materials are activated to effect enhanced penetration of the organic wood preservative into the wood. One may effect application at a solution temperature of about 30 to 75° C. and preferably about 50 to 60° C. to effect activation at a higher temperature and high relative humidity. In a preferred practice, the wood may be heated before and/or after application of the solution. The solution is also disclosed as a product.

    Abstract translation: 通过增强木材防腐剂渗透来保护木材的方法包括提供包含（a）至少一种氧化胺的溶液。 （b）至少一种有机木材防腐剂和（c）缓冲剂。 溶液优选具有约7至10的pH。将溶液施加到木材的表面，之后，在有或没有中间储存的情况下，材料被活化以增强有机木材防腐剂渗透到木材中。 可以在约30至75℃，优选约50至60℃的溶液温度下施用，以在更高的温度和较高的相对湿度下进行活化。 在优选的实践中，木材可以在施加溶液之前和/或之后被加热。 该解决方案也被公开为一种产品。

    Imidazopyrazinones as GABA-A receptor anxiolytics
    64.
    发明授权
    Imidazopyrazinones as GABA-A receptor anxiolytics 失效
    咪唑并吡嗪酮作为GABA-A受体抗焦虑药

    公开(公告)号：US07485640B2

    公开(公告)日：2009-02-03

    申请号：US10533152

    申请日：2003-10-29

    Applicant: William Robert Carling ,  Jose Luis Castro Pineiro ,  Simon Charles Goodacre ,  David James Hallett ,  Leslie Joseph Street

    Inventor： William Robert Carling ,  Jose Luis Castro Pineiro ,  Simon Charles Goodacre ,  David James Hallett ,  Leslie Joseph Street

    IPC: A01N43/64 ,  A01N43/90 ,  A61K31/53 ,  A61K31/519 ,  C07D253/08 ,  C07D487/00

    CPC classification number: C07D487/04

    Abstract: The present invention discloses a compound of formula I, or a pharmaceutically acceptable salt thereof: (I) wherein —U—V— represents —CH═CH—, or —CH2—CH2—, —N═CH— or —CH═N—; X1 represents hydrogen, halogen, C1-6 alkyl, trifluoromethyl or C1-6 alkoxy; X2 represents hydrogen or halogen; Y represents a chemical bond, an oxygen atom, or a —NH— or —OCH2— linkage; Z represents an optionally substituted aryl or heteroaryl group; R1 represents hydrocarbon, a heterocyclic group, trifluoromethyl, —SO2Ra, —SO2NRaRb, —CORa, —CO2Ra or —CONRaRb; and Ra and Rb independently represent hydrogen, hydrocarbon or a heterocyclic group; pharmaceutical compositions comprising it; its use in methods of treatment; use of it in the manufacture of a medicament for treating and/or preventing anxiety; convulsions or a cognitive disorder; and methods of treatment using it.

    Abstract translation: 本发明公开了式I化合物或其药学上可接受的盐：（I）其中-U-V-表示-CH-CH-或-CH 2 -CH 2 - ， - N-CH-或-CH-N-; X 1表示氢，卤素，C 1-6烷基，三氟甲基或C 1-6烷氧基; X2表示氢或卤素; Y代表化学键，氧原子或-NH-或-OCH2-键; Z表示任选取代的芳基或杂芳基; R1表示烃，杂环基，三氟甲基，-SO2Ra，-SO2NRaRb，-CORa，-CO2Ra或-CONRaRb; 并且R a和R b独立地表示氢，烃或杂环基; 包含它的药物组合物; 其用于治疗方法; 在制备用于治疗和/或预防焦虑的药物中的用途; 惊厥或认知障碍; 和使用它的治疗方法。

    Inclusion compound comprising cucurbituril derivatives as host molecule and pharmaceutical composition comprising the same
    66.
    发明授权
    Inclusion compound comprising cucurbituril derivatives as host molecule and pharmaceutical composition comprising the same 失效
    包含葫芦巴衍生物作为宿主分子的包含化合物和包含其的药物组合物

    公开(公告)号：US07459471B2

    公开(公告)日：2008-12-02

    申请号：US10489968

    申请日：2002-09-18

    Applicant: Kimoon Kim ,  Young Jin Jeon ,  Soo Young Kim ,  Young Ho Ko

    Inventor： Kimoon Kim ,  Young Jin Jeon ,  Soo Young Kim ,  Young Ho Ko

    IPC: C07D403/02 ,  A01N43/64 ,  A61K31/41

    CPC classification number: C07F15/0093

    Abstract: The present invention provides an inclusion compound having a cucurbituril derivative of the formula 1 as a host molecule and a metal complex of the formula 2 as a guest molecule. A pharmaceutical composition having an anticancer effect can be obtained by using the inclusion compound according to the present invention. The pharmaceutical composition can prevent effective components from being biologically degraded in vivo and can exhibit continuous drug effect for a long time just by a single dosage by controlling the release time of the platinum complex once it reaches target tumor cells.

    Abstract translation: 本发明提供具有作为主体分子的式1的葫芦巴衍生物和作为客体分子的式2的金属络合物的包合物。 通过使用本发明的包合物，可以得到具有抗癌作用的药物组合物。 药物组合物可以防止有效成分在体内生物降解，并且只要通过单一剂量通过控制铂络合物一旦达到靶肿瘤细胞的释放时间就可以长时间显示连续的药物作用。

    Method for Controlling Coniferous Plants
    70.
    发明申请
    Method for Controlling Coniferous Plants 审中-公开
    控制针叶植物的方法

    公开(公告)号：US20070293398A1

    公开(公告)日：2007-12-20

    申请号：US11631890

    申请日：2005-07-06

    Applicant: Cletus Youmans ,  Harold Quicke ,  Joseph Zawierucha ,  Larry Newsom

    Inventor： Cletus Youmans ,  Harold Quicke ,  Joseph Zawierucha ,  Larry Newsom

    IPC: A01N43/64 ,  A01N43/40 ,  A01N43/46 ,  A01N57/20 ,  A01N43/48

    CPC classification number: A01N43/54 ,  A01N61/00 ,  A01N57/20 ,  A01N43/50 ,  A01N37/40 ,  A01N2300/00

    Abstract: A method for controlling coniferous plants, wherein an effective amount of a) at least one phenyluracil of the formula I wherein the variables R1 to R7 are as defined in the specification; and optionally b) at least one herbicide B selected from groups B1 to B6 as defined in the specification, and/or at least one of the agriculturally acceptable salts of herbicide B or their agriculturally acceptable derivatives, provided they have a carboxyl group, is applied to coniferous plants to be controlled and/or to the parts of these plants, is described.

    Abstract translation: 一种用于控制针叶植物的方法，其中有效量的a）至少一种式I的苯基尿嘧啶，其中变量R 1至R 7如本说明书中所定义 ; 和任选的b）至少一种选自本说明书中定义的组B1至B6的除草剂B和/或至少一种除草剂B的农业上可接受的盐或其农业上可接受的衍生物，只要它们具有羧基即可。 描述了要控制的针叶植物和/或这些植物的部分。

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