公开(公告)号：US20180203082A1

公开(公告)日：2018-07-19

申请号：US15873781

申请日：2018-01-17

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Mingrui Yang ,  Debra McGivney

IPC: G01R33/54 ,  G06F17/30

CPC classification number: G01R33/54 ,  G01R33/5608 ,  G06F16/56 ,  G06F16/5838

Abstract: A system and method is provided for generating a map of a tissue property in a subject using magnetic resonance fingerprinting (MRF) and a compressed MRF dictionary, where the compressed MRF dictionary has a significantly reduced memory requirement relative to a standard MRF dictionary. The method includes performing a randomized singular value decomposition (rSVD) on a MRF dictionary to produce the compressed MRF dictionary. MRF data is then acquired and compared to the MRF dictionary to identify the tissue property from the region of interest in the subject. A tissue property map is then generated based on the tissue in the region of interest of the subject.

公开(公告)号：US12020667B2

公开(公告)日：2024-06-25

申请号：US17304371

申请日：2021-06-18

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Henry Eastman ,  Robert Gotschall

IPC: G09G5/14 ,  G02B27/01 ,  G06F3/01 ,  G06F3/0346 ,  G06T15/20 ,  G06T19/00 ,  H04L67/10

CPC classification number: G09G5/14 ,  G02B27/017 ,  G06F3/011 ,  G06F3/012 ,  G06F3/0346 ,  G06T15/20 ,  G06T19/00 ,  G06T19/006 ,  G02B2027/0134 ,  G06T2200/04 ,  G06T2200/24 ,  G06T2219/024 ,  G09G2354/00 ,  G09G2370/022 ,  H04L67/10

Abstract: Systems, methods, and media for displaying interactive augmented reality presentations are provided. In some embodiments, a system comprises: a head mounted display comprising: a transparent display; a plurality of sensors; and at least one processor, wherein the at least one processor is programmed to: select a content display location of a plurality of predetermined content display locations to use to present content based at least in part on a location of the head mounted display within a current physical environment; and cause content to be presented by the head mounted display anchored at the selected content display location.

公开(公告)号：US20240069134A1

公开(公告)日：2024-02-29

申请号：US18547549

申请日：2022-02-24

Applicant: Case Western Reserve University ,  Vanderbilt University

Inventor： Jonathan B. Martin ,  William A. Grissom ,  Mark A. Griswold

IPC: G01R33/483 ,  G01R33/54

CPC classification number: G01R33/4831 ,  G01R33/543

Abstract: A system and method is provided using a nuclear magnetic resonance (NMR) system. The method includes applying an off-resonance radio frequency (RF) pulse using a radio-frequency coil that is spatially inhomogeneous to induce a B1-dependent resonant frequency shift in spins in a subject and, in the presence of the off-resonance RF pulse, applying a frequency-modulated, frequency-selective RF excitation pulse to spatially encode the spins in the subject. The method also includes acquiring NMR data from the subject that is spatially encoded and reconstructing the NMR data to produce a report of internal materials forming the subject.

公开(公告)号：US20230288512A1

公开(公告)日：2023-09-14

申请号：US18181863

申请日：2023-03-10

Applicant: Case Western Reserve University

Inventor： Nicholas Reid Bolding ,  Mark A. Griswold

IPC: G01R33/54 ,  G01R33/381 ,  G01R33/421

CPC classification number: G01R33/543 ,  G01R33/381 ,  G01R33/4215

Abstract: The present disclosure provides transmit/receive (T/R) systems for NMR or MRI systems. In one configuration, the systems and methods provided herein may use passively-shielded coils that are compatible with low-field operational environment to replace conventional T/R systems and spatial gradient systems. In some configurations, a low-field imaging T/R system is provided that is designed for nuclear magnetic stimulation and local flux sensitivity, while automatically rejecting incident radiant electromagnetic noise. The design advantageously leverages low required frequencies to distribute the pulse synthesis task, yielding a smaller system with easier maintenance and lower cost. The system may include distributed coil nodes that include a primary radiofrequency (RF) coil configured to transmit and receive RF signals and a secondary coil configured to passively shield the primary RF coil.

公开(公告)号：US11385311B2

公开(公告)日：2022-07-12

申请号：US16858848

申请日：2020-04-27

Applicant: Case Western Reserve University

Inventor： Debra McGivney ,  Mark A. Griswold

IPC: G01R33/48 ,  G01R33/56 ,  G01R33/561

Abstract: A system and method is provided for improved magnetic resonance fingerprinting (MRF) data dictionary matching using an MRF dictionary having entries with an inner product storing tissue properties.

公开(公告)号：US20210312626A1

公开(公告)日：2021-10-07

申请号：US17301492

申请日：2021-04-05

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Dan Ma ,  Debra McGivney ,  Rasim Boyacioglu

IPC: G06T7/00 ,  G06T7/11 ,  G01R33/50 ,  G01R33/48 ,  G01R33/44 ,  G01R33/46 ,  G01R33/56

Abstract: A method for determining an undersampling error for a magnetic resonance fingerprinting (MRF) pulse sequence includes retrieving a plurality of sets of spatial response functions. Each set of spatial response functions is associated with a tissue type in a reference image and is based on a tissue mask of the reference image for each tissue type. A signal evolution for each tissue type may be generated based on, for example, the MRF pulse sequence, An undersampled image may be generated for each tissue type using the set of spatial response functions and the signal evolutions for the tissue type. At least one quantitative parameter may be determined by comparing an undersampled image series created from the undersampled images to an MRF dictionary. An undersampling error for the MRF pulse sequence may be generated by comparing a quantitative map (or maps) for the quantitative parameter (or parameters) and the reference image.

公开(公告)号：US11100696B2

公开(公告)日：2021-08-24

申请号：US16860014

申请日：2020-04-27

Applicant: Case Western Reserve University

Inventor： Andrew Dupuis ,  Mark A. Griswold

IPC: G06T15/00 ,  G06T15/08 ,  G06T15/06

Abstract: Systems, methods, and media for rendering voxel-based 3D content are provided. In some embodiments, a system for rendering voxel-based content comprises: a display; and hardware processor programmed to: receive voxel-based data representing an object at multiple different resolutions; perform, for a representation including low-resolution voxels, a first forward-projection ray marching operation with a step size based on the voxel volume; identify a voxel that causes a threshold to be exceeded; perform, for a second representation including higher-resolution voxels each smaller in volume than the first voxels, a second forward-projection ray marching operation; identify a second voxel in the second representation that causes the threshold to be exceeded; determine that the second representation is a highest resolution available; and cause a pixel to present a portion of the object based on a value associated with the second voxel.

公开(公告)号：USD921656S1

公开(公告)日：2021-06-08

申请号：US29736185

申请日：2020-05-28

Applicant: Case Western Reserve University

Designer： Mark A. Griswold

公开(公告)号：US10937391B2

公开(公告)日：2021-03-02

申请号：US16466122

申请日：2017-12-05

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Erin Henninger ,  Jeff Mlakar ,  Henry Eastman ,  Robert Gotschall ,  Catherine Sue Shick ,  Galen Tingle

IPC: G09G5/14 ,  G06F3/01 ,  G02B27/01 ,  G06F3/0346 ,  G06T15/20 ,  G06T19/00 ,  H04L29/08

Abstract: Systems, methods, and media for displaying interactive augmented reality presentations are provided. In some embodiments, a system comprises: a plurality of head mounted displays, a first head mounted display comprising a transparent display; and at least one processor, wherein the at least one processor is programmed to: determine that a first physical location of a plurality of physical locations in a physical environment of the head mounted display is located closest to the head mounted display; receive first content comprising a first three dimensional model; receive second content comprising a second three dimensional model; present, using the transparent display, a first view of the first three dimensional model at a first time; and present, using the transparent display, a first view of the second three dimensional model at a second time subsequent to the first time based one or more instructions received from a server.

公开(公告)号：US10859653B2

公开(公告)日：2020-12-08

申请号：US16169694

申请日：2018-10-24

Applicant: Case Western Reserve University

Inventor： Rasim Boyacioglu ,  Debra McGivney ,  Mark A. Griswold

IPC: G01R33/56 ,  G01R33/50 ,  G01R33/48 ,  G01R33/54

Abstract: Systems and methods are provided for Magnetic Resonance Fingerprinting (MRF) using Independent Component Analysis (ICA) to distinguish between different tissue types. In some configurations, an MRF acquisition may be performed to be sensitive to a selected tissue property or parameter, and tissues may be grouped into separate independent components based on their time courses which may be based on the underlying tissue property.