公开(公告)号：US10260059B2

公开(公告)日：2019-04-16

申请号：US15687800

申请日：2017-08-28

申请人： Zhejiang University of Technology ,  Zhejiang Chiral Medicine Chemicals Co. Ltd.

发明人： Renchao Zheng ,  Yuguo Zheng ,  Qin Zhang ,  Youming Huang ,  Jianfeng Weng ,  Tianchun Liu ,  Weirong Fan

IPC分类号： C12N9/78 ,  C12P13/00

摘要： The disclosure provides a nitrilase from Arabis alpina, which belongs to genus Arabis, family brassicaceae. The disclosure further provides the encoding gene, vector, recombinant bacterial strain, and the application in the manufacturing of (S)-3-cyano-5-methylhexanoic acid. The wet resting cells containing nitrilase Aa-Nit can kinetically resolve racemic IBSN at 1.2 M with a 42% conversion rate in 15 hr and >99% ee value. The disclosure provides a regio- and stereoselective method for the preparation of (S)-3-cyano-5-methylhexanoic acid. This method provides an atom economical, mild, environmental friendly industrial method to manufacture (S)-3-cyano-5-methylhexanoic acid.

公开(公告)号：US10246475B2

公开(公告)日：2019-04-02

申请号：US15709303

申请日：2017-09-19

申请人： Zhejiang University of Technology ,  AAC Microtech (Changzhou) Co., Ltd.

发明人： Guijie Li ,  Yuanbin She ,  Xiangdong Zhao ,  Shaohai Chen

IPC分类号： C09K11/06 ,  C07F15/00 ,  H01L51/00 ,  C09K11/02 ,  H01L51/50

摘要： Disclosed herein are multidentate dinuclear cyclometallated platinum complexes. The complexes are suitable as emitting materials or host materials in OLED devices, the materials having one of the following structures:

公开(公告)号：US10081590B2

公开(公告)日：2018-09-25

申请号：US15687470

申请日：2017-08-26

申请人： Zhejiang University of Technology

发明人： Yong Nie ,  Ying Duan ,  Ruchao Gong ,  Shangzhi Yu ,  Meizhen Lu ,  Jianbing Ji

IPC分类号： C07C67/333 ,  B01J19/12 ,  B01J8/02

CPC分类号： C07C67/333 ,  B01J8/0285 ,  B01J19/126 ,  B01J2208/00176 ,  B01J2208/00442 ,  B01J2208/0053 ,  B01J2219/0801 ,  B01J2219/0869 ,  B01J2219/0871 ,  B01J2219/0892 ,  B01J2219/1215 ,  B01J2219/1245 ,  Y02P20/123 ,  C07C69/533

摘要： A device and a process for producing undecylenic acid methyl ester using methyl ricinoleate as raw material are provided. The device comprises a feed pump, a raw material pre-heater, a microwave catalytic reactor, a microwave generator, a temperature controller and an infrared sensor, a condenser, a product tank and a discharge pump. The feed pump is connected with the raw material pre-heater, which is connected with the inlet of the microwave catalytic reactor. The outlet of the microwave catalytic reactor is connected with the condenser, which is connected to the product tank and the discharge pump. The microwave catalytic reactor is located in the microwave generator, which is connected with the temperature controller and the infrared sensor. The process is as follows: high-purity methyl ricinoleate, used as the raw material, is converted to methyl undecene and heptaldehyde by microwave-assisted pyrolysis process, followed by isolation and purification to produce methyl undecene.

公开(公告)号：US20170355975A1

公开(公告)日：2017-12-14

申请号：US15687700

申请日：2017-08-28

申请人： Zhejiang University of Technology ,  Zhejiang Chiral Medicine Chemicals Co. Ltd.

发明人： Renchao ZHENG ,  Yuguo ZHENG ,  Qin ZHANG ,  Youming HUANG ,  Jianfeng WENG ,  Tianchun LIU ,  Weirong FAN

IPC分类号： C12N9/78 ,  C12P13/00

CPC分类号： C12N9/78 ,  C12P13/002 ,  C12Y305/05001

摘要： The disclosure provides a nitrilase from Arabis alpina, which belongs to genus Arabis, family brassicaceae. The disclosure further provides the encoding gene, vector, recombinant bacterial strain, and the application in the manufacturing of (S)-3-cyano-5-methylhexanoic acid. The wet resting cells containing nitrilase Aa-Nit can kinetically resolve racemic IBSN at 1.2 M with a 42% conversion rate in 15 hr and >99% ee value. The disclosure provides a regio- and stereoselective method for the preparation of (S)-3-cyano-5-methylhexanoic acid. This method provides an atom economical, mild, environmental friendly industrial method to manufacture (S)-3-cyano-5-methylhexanoic acid.

公开(公告)号：US20160083807A1

公开(公告)日：2016-03-24

申请号：US14591740

申请日：2015-01-07

申请人： Zhejiang University of Technology

发明人： JIANMENG CHEN ,  DONGZHI CHEN ,  JIEXU YE ,  LIMEI HAN ,  YIMING SUN

IPC分类号： C12R1/40 ,  B01D53/84 ,  C12N1/20

CPC分类号： C12R1/40 ,  A62D3/02 ,  B01D53/84 ,  B01D2251/95 ,  B01D2257/708 ,  C12N1/20 ,  Y02A50/235 ,  Y02A50/2358

摘要： This invention has disclosed a pseudomonas putida strain as well as its microbial inoculum and application. Such strain is named as Pseudomonas putida S-1, which was preserved at China Center for Type Culture Collection (CCTCC) on Sep. 25, 2013 with the deposit number of CCTCC NO: M2013444. The strain of this invention takes isopropanol, ethanal, dipropyl disulfide, diethyl disulfide and propanethiol as the sole carbon source for effective degradation of substrate simultaneously with the energy growth. Furthermore, it can obtain a perfect growth in different cultivation modes owing to high substrate tolerance, which has laid down a solid foundation for engineering application for elimination of VOCs contained exhaust gas by means of biological purification.

摘要翻译： 本发明公开了恶臭假单胞菌菌株及其微生物接种物和应用。 这种菌株被命名为恶臭假单胞菌S-1，于2013年9月25日在中国养殖集中中心保存，CCTCC编号：M2013444。 本发明的菌株在能量生长的同时使用异丙醇，乙醛，二丙基二硫醚，二乙基二硫醚和丙硫醇作为唯一的碳源，用于有效降解底物。 此外，由于高的底物耐受性，可以在不同的培养模式下获得完美的生长，为通过生物净化消除含有废气的挥发性有机化合物的工程应用奠定了坚实的基础。

公开(公告)号：US20140013573A1

公开(公告)日：2014-01-16

申请号：US14027201

申请日：2013-09-14

申请人： Zhejiang University of Technology

发明人： Zichun LE ,  Wen DONG

IPC分类号： B23P17/04

CPC分类号： B23P17/04 ,  G02B27/62 ,  G21K1/065 ,  G21K2201/067 ,  Y10T29/49885

摘要： A method for manufacturing a compound refractive lens for focusing X-rays in two dimensions. The method includes the following steps: 1) manufacturing a mother lens; 2) manufacturing a daughter lens; and 3) assembling the mother lens and the daughter lens. The assembly of the mother lens and the daughter lens includes: aligning square embedded lens bodies of the daughter lens with square holes of the mother lens, respectively, for allowing the first parabola-shaped holes on the mother lens and the second parabola-shaped holes on the daughter lens to form an orthogonal structure; and inserting and pressing the square embedded lens bodies into the corresponding square holes, respectively. The method of the invention has advantages of high-precision for manufacturing and calibration of optical axis, and meanwhile the compound refractive lens manufactured based the method has high X-rays focusing efficiency.

摘要翻译： 一种用于制造用于在二维上聚焦X射线的复合折射透镜的方法。 该方法包括以下步骤：1）制造母镜; 2）制造女儿镜片; 和3）组装母体镜片和子镜片。 母体透镜和子透镜的组合包括：分别将子透镜的方形嵌入透镜体与母体透镜的方孔对准，以允许母体透镜上的第一抛物线形孔和第二抛物线形孔 在女儿镜头上形成正交结构; 并将方形嵌入式透镜体分别插入并按压到相应的方孔中。 本发明的方法具有制造和校准光轴高精度的优点，同时基于该方法制造的复合折射透镜具有高X射线聚焦效率。

公开(公告)号：US20060222534A1

公开(公告)日：2006-10-05

申请号：US11103451

申请日：2005-04-12

申请人： Jianbing Ji ,  Zhichao Xu ,  Yunliang Yu

发明人： Jianbing Ji ,  Zhichao Xu ,  Yunliang Yu

IPC分类号： F04B17/00

CPC分类号： B01D3/30

摘要： The equipment of high-gravity multi-rotors zigzag rotating beds according to the present invention comprises a casing, a gas inlet and a liquid outlet being provided at the bottom of the casing, a gas outlet and a liquid inlet being provided at the top of the casing, a rotating shaft being provided at the center of the casing and going through the top and the bottom of the casing, a plurality of rotors being installed in series on the rotating shaft and being arranged in layers from top to bottom, and a middle feed inlet being provided on the side of the casing and being communicated with zigzag channels. The rotor comprises a mobile disk fixed on the rotating shaft and an immobile disk fixed on the casing, A series of concentric mobile and immobile circular baffle-sheets are fitted on the mobile disk and the immobile disk respectively. The series of concentric mobile and immobile circular baffle-sheets with different diameters are arranged in staggered form to compose the zigzag channels, and the first passage is set at the downside of the rotor and the second passage is set at the center on the top of the rotor. The first and second passages are communicated with the zigzag channels, and the second passage on the top rotor in the casing is communicated with the gas outlet and the liquid inlet; the first passage of the bottom rotor in the casing is communicated with the gas inlet and the liquid outlet; the second passage of the other rotors is communicated with the first passage of the above rotor.

摘要翻译： 根据本发明的高重力多转子曲折旋转床的设备包括壳体，气体入口和设置在壳体底部的液体出口，气体出口和液体入口设置在顶部的 所述壳体，设置在所述壳体的中心并且穿过所述壳体的顶部和底部的旋转轴，多个转子，其串联地安装在所述旋转轴上并且从顶部到底部分层地布置， 中间进料口设置在壳体的侧面并与之字形通道连通。 转子包括固定在旋转轴上的移动盘和固定在壳体上的固定盘。一系列同心移动和不动圆形挡板分别安装在移动盘和固定盘上。 具有不同直径的同心移动和不动圆形挡板系列以交错形式布置以形成之字形通道，第一通道设置在转子的下侧，第二通道设置在转子顶部的中心 转子。 第一和第二通道与之字形通道连通，壳体顶部转子上的第二通道与气体出口和液体入口连通; 底部转子在壳体中的第一通道与气体入口和液体出口连通; 其他转子的第二通道与上述转子的第一通道连通。

公开(公告)号：US20240296528A1

公开(公告)日：2024-09-05

申请号：US18366604

申请日：2023-08-07

申请人： China Jiliang University ,  ZHEJIANG UNIVERSITY OF TECHNOLOGY

发明人： Gang Xiao ,  Jiawei Lu ,  Qibing Wang ,  Chen Li ,  Hao HU ,  Junbo Yao

IPC分类号： G06T5/00

CPC分类号： G06T5/70 ,  G06T2207/10028

摘要： A denoising method based on a multiscale distribution score for a point cloud includes: constructing a two-layer network model based on multiscale perturbation and point cloud distribution, where the two-layer network model includes a feature extraction module for extracting a feature of the point cloud and a displacement prediction module for predicting a displacement of a noise point; constructing a point cloud noise model for improving a denoising effect and retaining a sharp feature and avoiding reducing quality of point cloud data; extracting a global feature h by inputting the point cloud data into the feature extraction module; iteratively learning the displacement of the noise point by the displacement prediction module according to a feature obtained by the feature extraction unit; and defining a loss function of network training, and completing convergence under the condition that the loss function reaches a set threshold or a maximum number of iterations.

公开(公告)号：US11939599B2

公开(公告)日：2024-03-26

申请号：US17566373

申请日：2021-12-30

申请人： ZHEJIANG UNIVERSITY OF TECHNOLOGY

发明人： Yaping Xue ,  Feng Cheng ,  Jiamin Zhang ,  Shuping Zou ,  Jianmiao Xu ,  Yuguo Zheng

IPC分类号： C12N9/00 ,  C12N9/04 ,  C12N9/06 ,  C12P13/04 ,  G16B30/10

CPC分类号： C12N9/0016 ,  C12N9/0006 ,  C12P13/04 ,  G16B30/10 ,  C12Y104/01002 ,  C12Y104/01003 ,  C12Y104/01004

摘要： Disclosed are a gene mining method combining functional sequence and structure simulation, an NADH-preferring phosphinothricin dehydrogenase mutant and an application thereof. The gene mining method comprises the following steps: (1) analyzing a characteristic sequence which an NADH-type glutamate dehydrogenase should have; (2) searching a gene library based on the characteristic sequence; (3) performing clustering analysis and protein structure simulation on genes obtained by the searching; (4) selecting genes that feature high gene aggregation and a protein structure similar to that of the known phosphinothricin dehydrogenase as candidate genes. A wild-type phosphinothricin dehydrogenase with an amino acid sequence as set forth in SEQ ID No.2 derived from Lysinibacillus composti is obtained through the gene mining, and then mutated, and an NADH-preferring phosphinothricin dehydrogenase mutant is screened out, which has a mutation site selected from one of the following: (1) A144G-V375F-M91A; (2) A144G-V345A-M91A; (3) A144G. This mutant enzyme can be used for catalytic reaction with an inexpensive coenzyme NAD.

公开(公告)号：US20240049940A1

公开(公告)日：2024-02-15

申请号：US18359903

申请日：2023-07-27

申请人： INNOVATION RESEARCH INSTITUTE OF ZHEJIANG UNIVERSITY OF TECHNOLOGY, SHENGZHOU

发明人： Shuiqing ZHOU ,  Ding XIA ,  Yu LUO ,  Xi JIN ,  Zijian MAO ,  Tianle ZHANG

IPC分类号： A47L15/00 ,  A47L15/16 ,  A47L15/42 ,  A47L15/46 ,  A47L15/50

CPC分类号： A47L15/0047 ,  A47L15/16 ,  A47L15/4234 ,  A47L15/4214 ,  A47L15/4244 ,  A47L15/0036 ,  A47L15/0028 ,  A47L15/46 ,  A47L15/4287 ,  A47L15/4289 ,  A47L15/50 ,  A47L2401/09 ,  A47L2401/12 ,  A47L2401/17 ,  A47L2401/14 ,  A47L2501/06 ,  A47L2501/14 ,  A47L2501/01 ,  A47L2501/02

摘要： Disclosed in the present invention are an energy-saving dishwasher and a control method therefor. The inner container is arranged inside the housing, the inner container is internally provided with a manifold type dish rack for placing dishes and spraying steam to perform steam cleaning on the dishes, and the manifold type dish rack is placed on a supporting frame fixed to the inner container. A water storage tank, a steam/hot water integrated generating device and a water pump are arranged below the inner container, and the steam/hot water integrated generating device includes a generating assembly and a control assembly. The manifold type dish rack is configured to place the dishes and simultaneously sprays steam to clean the dishes. The steam/hot water integrated generating device is configured to generate steam and hot water, heating is performed to generate the steam, and then relative cooling is performed to generate the hot water.