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公开(公告)号:US09360484B2
公开(公告)日:2016-06-07
申请号:US14078241
申请日:2013-11-12
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/00 , G01N33/68 , A61K47/48 , C07K16/28 , G01N33/574 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/395 , A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US12281165B2
公开(公告)日:2025-04-22
申请号:US17677283
申请日:2022-02-22
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/68 , C07K16/30 , G01N33/574 , A61K39/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US12134649B2
公开(公告)日:2024-11-05
申请号:US17547528
申请日:2021-12-10
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K38/08 , A61K39/395 , A61K47/65 , A61K47/68 , A61K51/10 , A61P35/00 , C07K16/30 , G01N33/569 , A61K39/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US11000510B2
公开(公告)日:2021-05-11
申请号:US16358410
申请日:2019-03-19
Applicant: Genentech, Inc.
Inventor: Andrew Polson , Shang-Fan Yu , Yu-Waye Chu , Michael Wenger , Jamie Harue Hirata , Dan Lu
IPC: A61K39/00 , A61K31/4184 , A61K39/395 , A61K47/68 , A61K45/06 , C07K16/28 , C07K16/30 , A61K31/553 , A61K31/454 , A61K31/635
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号:US10556951B2
公开(公告)日:2020-02-11
申请号:US15918842
申请日:2018-03-12
Applicant: GENENTECH, INC.
Inventor: Shang-Fan Yu , Wei-Ching Liang , Yan Wu , Steven Leong , Andrew Polson
IPC: A61K39/395 , C07K16/28 , G01N33/574 , A61K47/68 , A61K39/00
Abstract: The invention provides anti-CD33 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10266597B2
公开(公告)日:2019-04-23
申请号:US15657472
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K31/5517 , A61K31/706 , A61K51/10 , C07K16/30 , G01N33/574 , A61K47/68
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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57.
公开(公告)号:US20180344848A1
公开(公告)日:2018-12-06
申请号:US16101203
申请日:2018-08-10
Applicant: Hoffmann-La Roche Inc. , Genentech, Inc.
Inventor: Christian Klein , Sabine Lang , Pablo Umana , Andrew Polson
IPC: A61K39/395 , A61K47/68 , A61K45/06 , A61K31/40 , C07K16/28
CPC classification number: A61K39/39558 , A61K31/40 , A61K31/5365 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/507 , C07K16/2803 , C07K16/2887 , C07K2317/41 , C07K2317/76
Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD79b antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD79b antibody-drug conjugate.
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公开(公告)号:US20180201679A1
公开(公告)日:2018-07-19
申请号:US15803495
申请日:2017-11-03
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC classification number: C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/412
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US09975949B2
公开(公告)日:2018-05-22
申请号:US14960015
申请日:2015-12-04
Applicant: Genentech, Inc.
Inventor: Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Andrew Polson
IPC: A61K39/395 , C07K16/28 , A61K47/68 , A61K39/00
CPC classification number: C07K16/2803 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2809 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/622 , C07K2317/92
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
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公开(公告)号:US09951133B2
公开(公告)日:2018-04-24
申请号:US15171128
申请日:2016-06-02
Applicant: GENENTECH, INC.
Inventor: Shang-Fan Yu , Wei-Ching Liang , Yan Wu , Steven Leong , Andrew Polson
IPC: A61K39/395 , C07K16/28 , A61K47/48 , G01N33/574 , A61K39/00
CPC classification number: C07K16/2803 , A61K47/6809 , A61K47/6849 , A61K2039/505 , C07K2317/33 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492 , G01N2333/70596 , G01N2458/00
Abstract: The invention provides anti-CD33 antibodies and immunoconjugates and methods of using the same.
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