公开(公告)号：US20100197662A1

公开(公告)日：2010-08-05

申请号：US11916173

申请日：2006-06-06

申请人： Tomoyuki Ogawa ,  Noriyuki Kurose ,  Satoru Tanaka ,  Koichi Nishi

发明人： Tomoyuki Ogawa ,  Noriyuki Kurose ,  Satoru Tanaka ,  Koichi Nishi

IPC分类号： A61K31/55 ,  C07D261/10 ,  A61K31/42 ,  C07D413/06 ,  C07D261/18 ,  A61K31/4439 ,  C07D413/12 ,  A61K31/454 ,  A61K31/538 ,  A61K31/4709 ,  A61K31/5377 ,  A61K31/529 ,  C07D453/02 ,  A61K31/439 ,  C07D413/14 ,  A61P3/10

CPC分类号： C07D261/10 ,  C07D261/18 ,  C07D413/06 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D471/10 ,  C07D487/08

摘要： Disclosed is a compound useful as a type I 11βhydroxysteroid dehydrogenase inhibitor. A compound represented by the formula: a pharmaceutically acceptable salt or solvate thereof, wherein R1 is optionally substituted cycloalkyl, optionally substituted cycloalkenyl or the like, One of R2 and R3 is a group of the formula: —C(═O)—Y—R4, wherein Y is —NR9— or the like, R4 is optionally substituted cycloalkyl or the like, R9 is hydrogen or optionally substituted alkyl, W is optionally substituted alkylene, The other is a group of the formula: —V—R5, wherein V is a bond, —O— or the like, R6 is hydrogen or optionally substituted alkyl, R5 is hydrogen, optionally substituted alkyl or the like, X is a bond, —S—, —SO— or the like, U is a bond or optionally substituted alkylene, R7 is hydrogen or optionally substituted alkyl, Z is —S—, —O— or —NR8—, R8 is hydrogen, optionally substituted alkyl or the like.

摘要翻译： 公开了可用作I 11和Bgr的羟基类固醇脱氢酶抑制剂的化合物。 由下式表示的化合物：其药学上可接受的盐或溶剂合物，其中R 1是任选取代的环烷基，任选取代的环烯基等，R 2和R 3中的一个是下式的基团：-C（= O）-Y- R4，其中Y是-NR9-等，R4是任选取代的环烷基等，R 9是氢或任选取代的烷基，W是任选取代的亚烷基，另一个是下式基团：-V-R5，其中 V是键，-O-等，R6是氢或任选取代的烷基，R 5是氢，任选取代的烷基等，X是一个键，-S-，-SO-等，U是 键或任选取代的亚烷基，R 7是氢或任选取代的烷基，Z是-S-，-O-或-NR 8 - ，R 8是氢，任选取代的烷基等。

公开(公告)号：US07663550B2

公开(公告)日：2010-02-16

申请号：US11353250

申请日：2006-02-14

申请人： Ken Takei ,  Tomoyuki Ogawa

发明人： Ken Takei ,  Tomoyuki Ogawa

IPC分类号： H01Q1/38

CPC分类号： H01Q9/16 ,  H01Q1/38 ,  H01Q9/28

摘要： A distributed phase type circular polarized wave antenna is composed of a group of narrow conductor lines 2a, 2b, 2c and 2d, and the group of the narrow conductor lines 2a, 2b, 2c and 2d are laid out in a two-dimensional plane. Complex vectorial sums of respective projections of current induced in each point of the narrow conductor lines 2a, 2b, 2c and 2d in two directions orthogonal to each other in the two-dimensional plane are determined, such that amplitudes of the complex vectorial sums are equal to each other in the two directions and a phase difference between the complex vectorial sums in the two directions is 90°.

摘要翻译： 分布相型圆偏振波天线由一组窄导体线2a，2b，2c和2d组成，并且窄导体线2a，2b，2c和2d的组被布置在二维平面中。 确定在二维平面中在彼此正交的两个方向上在窄导体线2a，2b，2c和2d的每个点中感应的电流的各个投影的复矢量和，使得复矢量和的幅度相等 并且在两个方向上的复矢量和之间的相位差为90°。

公开(公告)号：US20090131491A1

公开(公告)日：2009-05-21

申请号：US12293246

申请日：2007-03-28

申请人： Tomoyuki Ogawa ,  Nobuo Chomei ,  Koji Masuda ,  Satoru Tanaka

发明人： Tomoyuki Ogawa ,  Nobuo Chomei ,  Koji Masuda ,  Satoru Tanaka

IPC分类号： A61K31/42 ,  C07D261/02 ,  A61P3/10

CPC分类号： C07D261/18 ,  C07D275/02 ,  C07D413/12 ,  C07D417/12 ,  C07D471/10

摘要： Disclosed is a compound useful as an inhibitor of 11β-hydroxysteroid dehydrogenase type 1.A compound represented by the formula: a pharmaceutically acceptable salt or solvate thereof, wherein R1 is a group of the formula: —C(═O)NR4R5, (wherein R4 and R5 are each independently, hydrogen, optionally substituted alkyl or the like) or a group of the formula: —NR6C(═O)R7, (wherein R6 and R7 are each independently, hydrogen, optionally substituted alkyl or the like), X and Y are each independently —O— or the like, Z is a bond or the like, R2 is optionally substituted alkyl, optionally substituted alkenyl or the like, R3 is optionally substituted alkyl, optionally substituted alkenyl or the like.

摘要翻译： 公开了用作11β-羟类固醇脱氢酶1型抑制剂的化合物。下式表示的化合物：其药学上可接受的盐或溶剂合物，其中R 1是下式的基团：-C（-O）NR 4 R 5，（其中 R 4和R 5各自独立地为氢，任选取代的烷基等）或下式-NR 6 C（-O）R 7的基团（其中R 6和R 7各自独立地为氢，任选取代的烷基等）， X和Y各自独立地为-O-等，Z为键或类似物，R 2为任选取代的烷基，任选取代的烯基等，R 3为任选取代的烷基，任选取代的烯基等。

公开(公告)号：US07431785B2

公开(公告)日：2008-10-07

申请号：US10624537

申请日：2003-07-23

申请人： Katsuhiro Horikawa ,  Tomoyuki Ogawa

发明人： Katsuhiro Horikawa ,  Tomoyuki Ogawa

IPC分类号： C03B29/00 ,  B32B37/06 ,  H01L41/187 ,  C04B35/491

CPC分类号： C04B35/493 ,  C04B2235/3206 ,  C04B2235/3241 ,  C04B2235/3251 ,  C04B2235/3258 ,  C04B2235/3275 ,  C04B2235/3279 ,  C04B2235/3294 ,  C04B2235/6025 ,  C04B2235/656 ,  C04B2235/6584 ,  C04B2235/786 ,  C04B2235/79 ,  H01L41/083 ,  H01L41/1876 ,  H01L41/273

摘要： A monolithic piezoelectric part capable of yielding a high piezoelectric d constant and suppressing reduction in reliability such as deterioration in insulation resistance can be obtained by a method for manufacturing a monolithic piezoelectric part wherein a piezoelectric ceramic body is formed of a perovskite compound oxide expressed by the general formula of ABO3, and the molar quantity of the A site component, Pb, is reduced by about 0.5 mol % to 5.0 mol % from that of the stoichiometric composition, ceramic raw materials are combined so that the average valence of the B site component is greater than quadrivalent, which is the same as the stoichiometric composition, to synthesize the ceramic powdered raw material, which is processed subsequently to fabricate a layered article, and the layered article is subjected to sintering processing within an atmosphere wherein the oxygen concentration is about 5% or less but more than 0% by volume.

摘要翻译： 通过一种压电陶瓷体由钙钛矿复合氧化物形成的压电陶瓷体的制造方法可以获得能够产生高压电d常数并抑制诸如绝缘电阻劣化的可靠性降低的单片压电部件， ABO 3的通式和A位成分Pb的摩尔量与化学计量组成相比减少约0.5mol％至5.0mol％，将陶瓷原料组合使得 合成陶瓷粉末原料的B位成分的平均化合价大于与化学计量组成相同的四价值，随后加工成层状制品，层压制品经过烧结处理 其中氧浓度为约5％以下但大于0体积％的气氛。

公开(公告)号：US20070139270A1

公开(公告)日：2007-06-21

申请号：US10578769

申请日：2004-07-29

申请人： Ken Takei ,  Tomoyuki Ogawa ,  Morihiko Ikegaya ,  Keisuke Fukuchi

发明人： Ken Takei ,  Tomoyuki Ogawa ,  Morihiko Ikegaya ,  Keisuke Fukuchi

IPC分类号： H01Q1/38

CPC分类号： H01Q9/42 ,  H01Q1/243 ,  H01Q1/38 ,  H01Q5/357

摘要： A small antenna operating in multiple modes including three or more modes. There are provided an antenna that includes a ground conductor having a ground potential, a single feeding point whose one end is formed by a part of the ground conductor, and a plurality of transmission lines to which RF power supplied to the feeding point is input, the transmission lines each radiating electromagnetic waves of three frequencies of three modes into space. These transmission lines comprises a transmission line 41 that is connected to the feeding point at one end and to a branching point at the other end, a transmission line connected between branching points, and transmission lines connected to the branching points. The lengths of the respective transmission lines are set so that impedance matching is performed at the feeding point with respect to a plurality of frequencies. The antenna is formed from an integrated metal plate.

摘要翻译： 一种小型天线，在多种模式下工作，包括三种或更多种模式。 提供了一种天线，其包括具有接地电位的接地导体，其一端由接地导体的一部分形成的单个馈电点和输入到馈电点的RF功率的多个传输线， 传输线将三种三种模式的电磁波辐射到空间中。 这些传输线包括传输线41，其连接到一端的馈电点和另一端的分支点，连接在分支点之间的传输线和连接到分支点的传输线。 设定各传输线的长度，使得相对于多个频率在馈电点进行阻抗匹配。 天线由集成的金属板形成。

公开(公告)号：US20060267845A1

公开(公告)日：2006-11-30

申请号：US11431095

申请日：2006-05-10

申请人： Ken Takei ,  Tomoyuki Ogawa

发明人： Ken Takei ,  Tomoyuki Ogawa

IPC分类号： H01Q1/38 ,  H01Q1/24

CPC分类号： H01Q1/243 ,  H01Q1/36 ,  H01Q9/0407 ,  H01Q9/0414 ,  H01Q9/0428

摘要： A distributed phase type circular polarized wave antenna provided with a plane, a power feed point 4 formed on the plane; and narrow conductor groups 1, 2 composed of narrow conductors 101 having a substantially one-dimensional current distribution, the narrow conductor groups being distributed in two dimension on the plane, and sums of projections of complex vectors of current distributions induced on the narrow conductors in first and second directions orthogonal to each other defined on the plane are determined in amplitude and phase, such that amplitudes are approximately equal to each other and a phase difference is approximately 90°.

摘要翻译： 具有平面的分布相型圆偏振波天线，在该平面上形成的馈电点4; 以及由具有大致一维电流分布的窄导体101构成的窄导体组1,2，窄导体组在平面上分为二维，以及在窄导体上感应的电流分布的复矢量的投影总和 在幅度和相位上确定在平面上彼此定义的彼此正交的第一和第二方向，使得幅度彼此近似相等，相位差约为90°。

公开(公告)号：US20060097932A1

公开(公告)日：2006-05-11

申请号：US11252889

申请日：2005-10-19

申请人： Ken Takei ,  Tomoyuki Ogawa ,  Morihiko Ikegaya

发明人： Ken Takei ,  Tomoyuki Ogawa ,  Morihiko Ikegaya

IPC分类号： H01Q1/24

CPC分类号： H01Q1/243 ,  H01Q1/38

摘要： A small size thin type antenna using a thin type structure having a wavelength compaction effect without using a bulk conductive material and a high frequency module using the same are disclosed. The small size thin type antenna comprises an open stub 3 including at least one transmission line 13, 16, a connecting line 5 including at least one transmission line 15, and a short stub 4 including a transmission line 14. A characteristic impedance Zo of the open stub 3 is determined to be lower than a characteristic impedance Zb of the connecting line 5 and a characteristic impedance Zs of the short stub 4.

摘要翻译： 公开了一种使用不使用体导电材料的具有波长压实效应的薄型结构的小尺寸薄型天线，以及使用该天线的高频模块。 小尺寸薄型天线包括开口短截线3，其包括至少一个传输线13,16，包括至少一个传输线15的连接线5和包括传输线14的短短短截线4.特征阻抗Zo 开路短截线3被确定为低于连接线5的特性阻抗Zb和短截线4的特性阻抗Zs。

公开(公告)号：US06673781B1

公开(公告)日：2004-01-06

申请号：US10048348

申请日：2002-02-01

申请人： Mitsuaki Ohtani ,  Masahiro Fuji ,  Tetsuo Okada ,  Makoto Adachi ,  Tomoyuki Ogawa

发明人： Mitsuaki Ohtani ,  Masahiro Fuji ,  Tetsuo Okada ,  Makoto Adachi ,  Tomoyuki Ogawa

IPC分类号： C07D47104

CPC分类号： C07D471/04 ,  C07D471/14 ,  C07D491/14

摘要： The present invention provides a compound having sPLA2 inhibiting activity. The compound represented by the formula (I): wherein R1 is (a) C1 to C20 alkyl, C2 to C20 alkenyl, C2 to C20 alkynyl, carbocyclic groups, heterocyclic groups or the like; R2 is CONH2 or CONHNH2; one of R3 and R4 is —(L2)-(acidic group) wherein L2 is a group connecting with an acid group and the length of the connecting groups 1 to 5 atoms, and the other is a hydrogen atom; its prodrug, their pharmaceutically acceptable salt, or solvate thereof.

摘要翻译： 本发明提供具有sPLA2抑制活性的化合物。 由式（I）表示的化合物：其中R 1为（a）C 1至C 20烷基，C 2至C 20烯基，C 2至C 20炔基，碳环基，杂环基等; R 2是CONH 2或CONHNH 2; R 3和R 4之一是 - （L 2） - （酸性基团）其中L 2是与酸基连接的基团和连接基团的长度为1至5个原子，以及 另一个是氢原子; 其前体药物，其药学上可接受的盐或溶剂化物。

公开(公告)号：US20140085023A1

公开(公告)日：2014-03-27

申请号：US14113711

申请日：2012-04-26

申请人： Migaku Takahashi ,  Tomoyuki Ogawa ,  Yasunobu Ogata ,  Naoya Kobayashi ,  Chammika Ruwan Polwatta Gallage ,  Kaori Kohara

发明人： Migaku Takahashi ,  Tomoyuki Ogawa ,  Yasunobu Ogata ,  Naoya Kobayashi ,  Chammika Ruwan Polwatta Gallage ,  Kaori Kohara

IPC分类号： H01F1/01 ,  H01F41/02

CPC分类号： H01F1/01 ,  B22F9/22 ,  C01B21/0622 ,  C01P2004/51 ,  C01P2004/54 ,  C01P2006/12 ,  C01P2006/42 ,  C22C38/001 ,  C22C2202/02 ,  H01F1/065 ,  H01F1/083 ,  H01F41/0266

摘要： The present invention relates to ferromagnetic particles capable of exhibiting a high purity and excellent magnetic properties from the industrial viewpoints and a process for producing the ferromagnetic particles, and also provides an anisotropic magnet, a bonded magnet and a compacted magnet which are obtained by using the ferromagnetic particles. The ferromagnetic particles comprising an Fe16N2 compound phase in an amount of not less than 80% as measured by Mössbauer spectrum and each having an outer shell in which FeO is present in the form of a layer having a thickness of not more than 5 nm according to the present invention can be produced by subjecting aggregated particles of an iron compound as a starting material whose primary particles have a ratio of [(average deviation of major axis lengths of particles)/(average major axis length of particles)] of not more than 50%, Uc of not more than 1.55, Cg of not less than 0.95, Cg2 of not less than 0.40, an average major axis length of 40 to 5000 nm, and an aspect ratio (major axis diameter/minor axis diameter) of 1 to 200, to dispersing treatment; then subjecting the iron compound particles passed through a mesh screen to reducing treatment at a temperature of 160 to 420° C.; and subjecting the resulting particles to nitridation treatment at a temperature of 130 to 170° C.

摘要翻译： 本发明涉及从工业观点出发具有高纯度和优异磁特性的铁磁性颗粒以及制造铁磁性颗粒的方法，并且还提供了各向异性磁体，粘结磁体和压实磁体，它们通过使用 铁磁颗粒。 铁磁性颗粒包含通过Mössbauer光谱测量的不小于80％的Fe 16 N 2化合物相，并且每个具有外壳，其中FeO以厚度不大于5nm的层的形式存在，根据 本发明可以通过使铁化合物的凝集颗粒作为起始材料，其一次颗粒具有[（颗粒的长轴长度的平均偏差）/（颗粒的平均长轴长度）]的比例不大于 50％，Uc为1.55以下，Cg为0.95以上，Cg2为0.40以上，平均长轴长为40〜5000nm，纵横比（长轴径/短轴直径）为1 至200，分散处理; 然后使经过筛网的铁化合物粒子在160〜420℃的温度下进行还原处理。 并在130-170℃的温度下对所得颗粒进行氮化处理。

公开(公告)号：US20140012013A1

公开(公告)日：2014-01-09

申请号：US14005710

申请日：2012-03-15

申请人： Masaaki Uenaka ,  Shuji Yonezawa ,  Akira Iida ,  Mutsumi Takaki ,  Tomoyuki Ogawa ,  Satoshi Goda ,  Yoshikatsu Hirose ,  Tomohiro Fukuda

发明人： Masaaki Uenaka ,  Shuji Yonezawa ,  Akira Iida ,  Mutsumi Takaki ,  Tomoyuki Ogawa ,  Satoshi Goda ,  Yoshikatsu Hirose ,  Tomohiro Fukuda

IPC分类号： C07D231/20

CPC分类号： C07D231/20 ,  C07C243/16 ,  C07D413/06 ,  C07C241/02

摘要： Disclosed is a process for producing a pyrazole carboxylic acid derivative which is useful as a significant intermediate of an 11βHSD-1 inhibitor.A compound represented by the Formula (XI): is useful as a significant intermediate of an 11βHSD-1 inhibitor, wherein R1 and R2 are each independently hydrogen or substituted or unsubstituted alkyl, R3 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocyclyl and R4 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocyclyl.

摘要翻译： 公开了一种制备吡唑羧酸衍生物的方法，其可用作11betaHSD-1抑制剂的重要中间体。 由式（XI）表示的化合物可用作11betaHSD-1抑制剂的显着中间体，其中R 1和R 2各自独立地为氢或取代或未取代的烷基，R 3为取代或未取代的烷基，取代或未取代的烯基，被取代的 取代或未取代的环烷基，取代或未取代的芳基，取代或未取代的杂芳基或取代或未取代的杂环基，R4是取代或未取代的烷基，取代或未取代的烯基，取代或未取代的炔基，取代或未取代的环烷基 取代或未取代的环烯基，取代或未取代的芳基，取代或未取代的杂芳基或取代或未取代的杂环基。