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公开(公告)号：US20190029981A1
公开(公告)日：2019-01-31
申请号：US16071530
申请日：2017-01-26
申请人： NESTEC S.A.
发明人： Carine Blanchard , Chiara Nembrini
IPC分类号： A61K31/19 , A23L33/12 , A23L33/135 , A61P17/00
CPC分类号： A61K31/19 , A23L33/12 , A23L33/135 , A23V2002/00 , A23V2200/318 , A23V2200/3204 , A23V2250/1884 , A61K31/702 , A61K2035/115 , A61P17/00
摘要： The present invention relates to the use in a pregnant or lactating woman of SFCA ingredient, SCFA originating ingredients or mixtures thereof for preventing and/or treating trans epidermal water loss (TEWL) and/or TEWL-associated disorders and/or enhance skin barrier function in the off-spring or breast-fed infant.
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42.发明授权公开(公告)号：US10081801B2
公开(公告)日：2018-09-25
申请号：US14783967
申请日：2014-04-11
发明人： Jørn Dalgaard Mikkelsen , Carsten Jers , Malwina Michalak , Kasper Planeta Kepp , Dorte Møller Larsen
IPC分类号： C12N9/24 , A61K31/70 , A61K31/7016 , A61K31/702 , A23L33/00 , A23L33/10
CPC分类号： C12N9/2402 , A23L33/10 , A23L33/40 , A23V2002/00 , A61K31/7016 , A61K31/702 , C12Y302/01018 , Y02A50/414 , Y02P20/582
摘要： The invention provides a mutant enzyme having trans-sialidase activity (EC 3.2.1.18), characterized by an enhanced trans-sialidase:sialidase ratio when compared to its parent sialidase enzyme. Further the enzyme may be used in a method for trans-sialylating mono- and oligo-saccharides, including galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), malto-oligosaccharides (MOS), isomalto-oligosaccarides (IMO), lactulose, melibiose, maltose, glycosyl sucrose, lactosucrose and fucose. Trans-sialidated mono- and oligo-saccharides, produced with the mutant enzyme, are useful in preparing infant formula, a prebiotic nutritional supplement, and a food supplement.
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公开(公告)号：US20180250324A1
公开(公告)日：2018-09-06
申请号：US15710716
申请日：2017-09-20
IPC分类号： A61K31/715 , A61K31/7004 , A61K31/7016 , A23L33/21 , A61K9/48 , A61K35/741 , A23L33/135 , A61K31/702 , A61K35/745 , A61K35/747
CPC分类号： A61K31/715 , A23L33/135 , A23L33/21 , A23V2002/00 , A23Y2220/00 , A23Y2300/00 , A61K9/4825 , A61K31/7004 , A61K31/7016 , A61K31/702 , A61K35/741 , A61K35/745 , A61K35/747 , Y02A50/473 , A61K2300/00 , A23V2200/32 , A23V2200/3202 , A23V2200/3204
摘要： The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.
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公开(公告)号：US20180243195A1
公开(公告)日：2018-08-30
申请号：US15756698
申请日：2016-09-01
CPC分类号： A61K8/602 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/49 , A61K8/498 , A61K8/60 , A61K9/08 , A61K9/16 , A61K9/20 , A61K31/19 , A61K31/198 , A61K31/353 , A61K31/702 , A61K31/7048 , A61Q19/00 , A61Q19/02
摘要： [Object] The present invention has an object to provide an external dermal agent for reducing skin yellowness already generated in the skin.[Means to Attain the Object] The above object is solved by providing an external dermal agent for reducing skin yellowness already generated in the skin, which contains hesperetin and/or glycosyl hesperetin as an effective ingredient(s).
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45.发明申请公开(公告)号：US20180161353A1
公开(公告)日：2018-06-14
申请号：US15893112
申请日：2018-02-09
申请人： ABBOTT LABORATORIES
IPC分类号： A61K31/702 , A23L33/00 , A23L33/12 , A61K31/7016 , A61K31/202 , A61K45/06
CPC分类号： A61K31/702 , A23L33/12 , A23L33/40 , A23V2002/00 , A23V2200/3202 , A23V2200/324 , A23V2250/1882 , A23V2250/28 , A61K31/202 , A61K31/7016 , A61K45/06 , A61K2300/00
摘要： Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
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46.发明申请公开(公告)号：US20180161351A1
公开(公告)日：2018-06-14
申请号：US15892169
申请日：2018-02-08
申请人： ABBOTT LABORATORIES
IPC分类号： A61K31/702 , A23L33/00 , A23L33/12 , A61K31/7016 , A61K31/202 , A61K45/06
CPC分类号： A61K31/702 , A23L33/12 , A23L33/40 , A23V2002/00 , A23V2200/3202 , A23V2200/324 , A23V2250/1882 , A23V2250/28 , A61K31/202 , A61K31/7016 , A61K45/06 , A61K2300/00
摘要： Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
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公开(公告)号：US20180153923A1
公开(公告)日：2018-06-07
申请号：US15646746
申请日：2017-07-11
申请人： N.V. Nutricia
发明人： Gelske SPEELMANS , Maria Johanna Adriana Petronella GOVERS , Jan KNOL , Eric Alexander Franciscus VAN TOL
IPC分类号： A61K31/733 , A23L29/30 , A23L29/244 , A61K31/715 , A23L33/22 , A23L33/00 , A23L33/10 , A61K31/01 , A61K31/702
CPC分类号： A61K31/733 , A23L5/00 , A23L7/00 , A23L29/244 , A23L29/30 , A23L33/10 , A23L33/125 , A23L33/22 , A23L33/40 , A23V2002/00 , A23V2200/318 , A61K31/01 , A61K31/702 , A61K31/715 , A61K2300/00 , A23V2250/28 , A23V2250/5046 , A23V2200/3202 , A23V2250/5062 , A23V2200/304
摘要： The present invention relates to the field of prebiotics. Provided are uses for compositions comprising synergistically effective amounts of polyfructose and galactooligosaccharides (GOS).
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48.发明申请公开(公告)号：US20180127359A1
公开(公告)日：2018-05-10
申请号：US15806952
申请日：2017-11-08
申请人： NovoMedix, LLC
IPC分类号： C07C279/04 , A61K9/28 , A61K31/155 , A61K45/06 , A61P9/12 , A61P9/00 , A61P3/10
CPC分类号： C07C279/04 , A61K9/28 , A61K31/155 , A61K31/426 , A61K31/427 , A61K31/4439 , A61K31/4985 , A61K31/522 , A61K31/64 , A61K31/70 , A61K31/702 , A61K38/26 , A61K45/06 , A61P3/10 , A61P9/00 , A61P9/12 , C07B2200/13 , A61K2300/00
摘要： Provided herein are nitrite salts of 1,1-dimethylbiguanide; and isotopic variants thereof; and pharmaceutically acceptable hydrates and solvates thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of diseases associated with and/or caused by an abnormal blood glucose level. Further provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a cardiovascular disease.
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49.发明申请公开(公告)号：US20180078572A1
公开(公告)日：2018-03-22
申请号：US15554621
申请日：2016-03-04
申请人： NESTEC S.A.
IPC分类号： A61K31/702 , A23L33/125 , A23L33/135 , A23L33/00 , A61K9/00 , A61K35/741
CPC分类号： A61K31/702 , A23L33/125 , A23L33/135 , A23L33/21 , A23L33/40 , A23V2002/00 , A61K9/0056 , A61K35/741 , A61K2035/115 , A23V2200/3202 , A23V2250/28
摘要： The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide, for use in preventing and/or treating constipation and/or in improving stool consistency/frequency in an infant or a young child.
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50.发明申请公开(公告)号：US20180055864A1
公开(公告)日：2018-03-01
申请号：US15804751
申请日：2017-11-06
申请人： ABBOTT LABORATORIES
IPC分类号： A61K31/702 , A61K31/202 , A61K31/7016 , A23L33/12 , A61K45/06 , A23L33/00
CPC分类号： A61K31/702 , A23L33/12 , A23L33/40 , A23V2002/00 , A23V2200/3202 , A23V2200/324 , A23V2250/1882 , A23V2250/28 , A61K31/202 , A61K31/7016 , A61K45/06 , A61K2300/00
摘要： Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
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