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    Valved cartridge and system
    43.
    发明授权
    Valved cartridge and system 有权

    公开(公告)号：US10233491B2

    公开(公告)日：2019-03-19

    申请号：US15173894

    申请日：2016-06-06

    Applicant: IntegenX Inc.

    Inventor： Philip Justus Wunderle ,  Chungsoo Charles Park ,  David King ,  Dennis Lehto

    IPC: C12Q1/6874 ,  C12Q1/686 ,  B01L3/00 ,  F16K99/00 ,  B01L7/00 ,  B01F13/00 ,  B01F13/02

    Abstract: This disclosure provides, among other things, a cartridge comprising: (a) a cartridge body comprising a malleable material and having, disposed on a surface of the body, at least one valve body comprising a valve inlet and a valve outlet, each fluidically connected to a fluidic channel; and (b) a layer comprising a deformable material bonded to a surface of the cartridge body and sealing the at least one valve body at points of attachment, thereby forming at least one valve; wherein the at least one valve body is depressed in the cartridge body relative to the points of attachment and wherein the deformable material covering the at least one valve body retains sufficient elasticity after deformation such that in a ground state the valve is open. Also disclosed is an instrument comprising a cartridge interface and a cartridge as described herein engaged with the cartridge interface, wherein (II) the cartridge interface comprises: (A) at least one mechanical actuator, each mechanical actuator positioned to actuate a valve; and (B) at least one motor operatively coupled to actuate a mechanical actuator toward or away from a valve.

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