Patent search ap:("Genentech Page Inc.") AND inv:"Napoleone Ferrara"

41.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20030049633A1

公开(公告)日：2003-03-13

申请号：US09978585

申请日：2001-10-16

Applicant: Genentech, Inc.

Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood

IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , A61K038/17 , C12P021/02 , C12N005/06 , C07K014/435

CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

42.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 失效

公开(公告)号：US20030045693A1

公开(公告)日：2003-03-06

申请号：US09903749

申请日：2001-07-11

Applicant: Genentech, Inc.

Inventor： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood

IPC: C07H021/02 , C07H021/04

CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

43.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 有权

公开(公告)号：US20030044841A1

公开(公告)日：2003-03-06

申请号：US10006856

申请日：2001-12-06

Applicant: Genentech, Inc.

Inventor： Kevin` P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood

IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12N005/06 , C12P021/02 , C07K014/435 , C07K016/40

CPC classification number: C07K14/47 , C07K14/705

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

44.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 有权

公开(公告)号：US20030039969A1

公开(公告)日：2003-02-27

申请号：US09904786

申请日：2001-07-12

Applicant: Genentech, Inc.

Inventor： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood

IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435

CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

45.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20030032057A1

公开(公告)日：2003-02-13

申请号：US10002796

申请日：2001-11-15

Applicant: GENENTECH, INC.

Inventor： Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang

IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K016/40 , C07K014/435

CPC classification number: A61K38/17 , C07H21/04 , C07K14/435 , C07K16/40 , C12N5/06 , C12N9/00 , C12P21/02 , C12P21/06 , G01N33/53 , Y02A50/473

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

46.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20030027985A1

公开(公告)日：2003-02-06

申请号：US09990562

申请日：2001-11-14

Applicant: GENENTECH, INC.

Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang

IPC: A61K038/17 , C07K014/435 , C12N005/06 , C12P021/02 , C12Q001/68 , C07H021/04 , C12N009/00

CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

47.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20030027143A1

公开(公告)日：2003-02-06

申请号：US09906838

申请日：2001-07-16

Applicant: Genentech, Inc.

Inventor： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood

IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , A61K038/17

CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

48.

发明申请
Vascular endothelial cell growth factor antagonists 审中-公开
Title translation: 血管内皮细胞生长因子拮抗剂

公开(公告)号：US20030023046A1

公开(公告)日：2003-01-30

申请号：US10246875

申请日：2002-09-18

Applicant: Genentech, Inc.

Inventor： Napoleone Ferrara , Kyung Jin Kim

IPC: C07K016/22 , A61K039/395

CPC classification number: C07K14/52 , A61K38/00 , A61K2039/505 , C07K16/22 , C07K2317/73

Abstract: The present invention provides vascular endothelial cell growth factor (hVEGF) antagonists, including monoclonal antibodies, hVEGF receptors, and hVEGF variants that inhibit the mitogenic, angiogenic, or other biological activity of hVEGF. The antagonists thus are useful for the treatment of diseases and disorders characterized by undesirable or excessive endothelial cell proliferation or neovascularization. The monoclonal antibodies and receptors of the invention also are useful in diagnostic and analytical methods for determining the presence of hVEGF in a test sample.

Abstract translation: 本发明提供血管内皮细胞生长因子（hVEGF）拮抗剂，包括抑制hVEGF的促有丝分裂，血管生成或其他生物学活性的单克隆抗体，hVEGF受体和hVEGF变体。因此，拮抗剂可用于治疗以不良或过量的内皮细胞增殖或新生血管形成为特征的疾病和病症。本发明的单克隆抗体和受体也可用于确定测试样品中hVEGF的存在的诊断和分析方法。