-
公开(公告)号:US09567559B2
公开(公告)日:2017-02-14
申请号:US15238624
申请日:2016-08-16
发明人: Bart Lipkens , Louis Masi , Stanley Kowalski, III , Walter M. Presz, Jr. , Jason Dionne , Brian Dutra , Ari Mercado , Thomas J. Kennedy, III , Arthur Martin
CPC分类号: C12M47/10 , B01D17/04 , B01D17/06 , B01D21/283 , B06B1/0644 , C12M23/14 , C12M23/22 , C12M27/00 , C12M27/02 , C12M29/18 , C12M33/08 , C12M33/14 , C12M35/04 , C12M47/02 , C12M47/04 , C12P21/02
摘要: A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.
摘要翻译: 灌注生物反应器包括至少一个可声学地产生多维驻波的超声换能器。 驻波可用于将细胞保留在生物反应器中,并且也可用于从生物反应器中生产的废物中脱水或进一步收获产品。
-
42.
公开(公告)号:US20170008029A1
公开(公告)日:2017-01-12
申请号:US15206244
申请日:2016-07-09
发明人: Bart Lipkens , Walter M Presz, JR. , Kedar Chitale , Thomas J Kennedy, III , Rudolf Gilmanshin , Dane Mealey , Brian Dutra , David Sokolowski
CPC分类号: B06B1/0238 , B01D21/0009 , B01D21/283 , B06B1/0644 , B06B3/04 , C12M47/02 , H03H9/17
摘要: An acoustophoretic device is disclosed. The acoustophoretic device includes an acoustic chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer includes a piezoelectric material driven by a voltage signal to create a multi-dimensional acoustic standing wave in the acoustic chamber emanating from a non-planar face of the piezoelectric material. A method for separating a second fluid or a particulate from a host fluid is also disclosed. The method includes flowing the mixture through an acoustophoretic device. A voltage signal is sent to drive the ultrasonic transducer to create the multi-dimensional acoustic standing wave in the acoustic chamber such that the second fluid or particulate is continuously trapped in the standing wave, and then agglomerates, aggregates, clumps, or coalesces together, and subsequently rises or settles out of the host fluid due to buoyancy or gravity forces, and exits the acoustic chamber.
摘要翻译: 公开了一种声学设备。 声波装置包括声室,超声波换能器和反射器。 超声波换能器包括由电压信号驱动的压电材料,以在从压电材料的非平面发出的声室中产生多维声驻波。 还公开了用于从主体流体分离第二流体或颗粒的方法。 该方法包括使混合物流过声波装置。 发送电压信号以驱动超声波换能器以在声学室中产生多维声驻波,使得第二流体或颗粒被连续捕获在驻波中,然后聚集,聚集,聚集或聚结在一起, 并随后由于浮力或重力而升高或沉降在主流体之外,并离开声室。
-
公开(公告)号:US20160129370A1
公开(公告)日:2016-05-12
申请号:US15000573
申请日:2016-01-19
发明人: Bart Lipkens , Jason Dionne , Ari Mercado , Brian Dutra , Walter M. Presz, JR. , Thomas J. Kennedy, III , Louis Masi
IPC分类号: B01D17/04
CPC分类号: B01D17/04 , B01D43/00 , B06B1/0644 , C12M47/02
摘要: An acoustic standing wave is utilized to separate components from a multi-component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.
-
-