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公开(公告)号:US20210207754A1
公开(公告)日:2021-07-08
申请号:US17130167
申请日:2020-12-22
Inventor: Jianfeng ZHANG , Rachel Z. PYTEL , Jian L. DING
Abstract: A profile includes: a sidewall, a lumen for a fluid path, and an end, the profile including a thermoset material, wherein the profile includes a sealed end without an external bonding material, wherein the sealed end withstands a seal integrity pressure test of at least 1 psi, such as at least 5 psi, such as at least 10 psi, such as at least 15 psi, or even at least 20 psi air pressure for about 30 minutes under dry and wet conditions.
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公开(公告)号:US20210199532A1
公开(公告)日:2021-07-01
申请号:US17136658
申请日:2020-12-29
Inventor: Charles S. Golub , Raymond Alan Carr , Stéphane Domy , Mark Kelly , Robert Moreno
IPC: G01M3/18 , G06F3/041 , G06F3/0488 , H04Q9/02
Abstract: A method of monitoring at least one leak detection sensor, the method including the steps of: determining via a communication hub a first state of a sensor comprising a first condition when the sensor is dry and a second condition when the sensor is wet; determining via the communication hub a second state representing an operability of the sensor; communicating via the communication hub each of the states of the sensor to a Graphical User Interface (GUI); and displaying, via the GUI, a representation of the first and second states of the sensor.
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公开(公告)号:US20210199203A1
公开(公告)日:2021-07-01
申请号:US17111849
申请日:2020-12-04
Inventor: Herman M. DUBOIS , Philippe Burlot , Jan Kustermans , Filip Rousseau , Simone Caglio , Denis Fernandez , Christophe Valdenaire
Abstract: Systems and methods are disclosed that include providing a valve suitable for maintaining a seal and preventing fluid flow through the valve at cryogenic temperatures. The valve includes a valve body having a longitudinal axis along a flow path through the valve, a ball selectively rotatable within the valve body to selectively allow fluid flow through the valve, a seat formed within the valve body and comprising a cavity having an angled wall, and a seat insert at least partially disposed within the cavity and having a first sealing surface that forms a first sealing interface with the ball to prevent leakage through a first leakage path and a second sealing surface that forms a second sealing interface with the angled wall to prevent leakage through a second leakage path when the ball valve is selectively rotated to prevent fluid flow through the valve.
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公开(公告)号:US20210198606A1
公开(公告)日:2021-07-01
申请号:US17136400
申请日:2020-12-29
Inventor: Katie Campbell , Natalie Fekete , Rachel Z. Pytel
Abstract: This disclosure relates generally to containers (such as bags) having surfaces comprising one or more aptamer sequences. More particularly, the present disclosure relates to containers such as bags comprising a fluoropolymer attached to aptamer sequences having binding affinity for one or more biological agents, and to transductions methods using such containers. In one aspect, the disclosure provides a container (e.g., a bag) having an outer surface and an inner surface, the inner surface comprising a fluoropolymer; attached to the fluoropolymer, a plurality of functional groups; and attached to each of at least a portion of the functional groups, a first aptamer sequence having a binding affinity for a viral vector.
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公开(公告)号:US20210197530A1
公开(公告)日:2021-07-01
申请号:US17120604
申请日:2020-12-14
Inventor: Antoine DIGUET , Daniele COSTANTINI , Jean-Baptiste LAUDEREAU
IPC: B32B15/095 , B32B3/12 , B32B27/06 , B32B27/40
Abstract: A composite film may include a discontinuous silver-based functional film, and a TPU over-layer overlying the discontinuous silver-based functional film. The composite film may have an R/sq value of at least about 30 Ohm/sq.
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公开(公告)号:US20210178506A1
公开(公告)日:2021-06-17
申请号:US16952414
申请日:2020-11-19
Inventor: Jianfeng ZHANG , Rachel Z. Pytel , Anthony P. Pagliaro , Clemens E. Zoellner , Jian L. Ding , Thomas R. Nixon
Abstract: Systems and methods are disclosed that include generating a plasma treatment and applying the plasma treatment to end contact surfaces of a first profile and a second profile in a sterile environment, manipulating at least one of the first profile and the second profile to force contact between the end contact surface of the first profile and the end contact surface of the second profile to permanently connect, join, or weld the end contact surfaces of the first profile and the second profile together, thereby forming a sterile connection between the first profile and a second profile.
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公开(公告)号:US20210140473A1
公开(公告)日:2021-05-13
申请号:US17091508
申请日:2020-11-06
Inventor: Vincent Dimartino , Alan F. Hunter , Devika Ranganathan , Brandon S. Murphy
Abstract: A bearing including a bearing sidewall including a first circumferential end including an apex region, and a second circumferential end including a nadir region, where the first circumferential end and the second circumferential end are adapted to contact each other to form an interface, where at least one of the apex region or the nadir region includes a void to prevent contact between the apex region of the first circumferential end and the nadir region of the second circumferential end, where the bearing sidewall includes a substrate and a low friction material, and where at least one of the first circumferential end or the second circumferential end comprises an end face that is free of low friction material.
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公开(公告)号:US11002391B2
公开(公告)日:2021-05-11
申请号:US16397700
申请日:2019-04-29
Inventor: Craig J. Cronin , Mark W. Armitage , Dallas Conway
IPC: F16L27/12 , F16J15/16 , F16J15/18 , F16L17/035 , F16J15/56 , F16J15/3236
Abstract: The present invention is directed to a high-pressure bi-directional sealing system having circumferentially extending outer support rings (1520, 1900), annular, axial seals (1600, 1800) between the outer support rings (1520, 1900) and a circumferentially extending inner support ring (1700) located between the annular, axial seals (1600, 1800). The outer support rings (1520, 1900), seals (1600, 1800), and circumferentially extending inner support ring (1700) are located within a space between an outer tube (1502) and an inner tube (1504) that is telescopically disposed within the outer tube (1502). Seals (1600) and (1800) are oriented in opposite directions. Specifically, the opening of seal (1600) is facing in a first direction and the opening of seal (1800) is facing in a second direction that is opposite the first direction. This configuration enables the high-pressure bi-directional sealing system to handle pressure in both directions.
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公开(公告)号:US10968318B2
公开(公告)日:2021-04-06
申请号:US16236608
申请日:2018-12-30
Inventor: Jianfeng Zhang , Jian L. Ding , Ying Wang , Xipeng Liu
IPC: C08G77/14 , C09J183/06 , C09D183/06 , C09D183/04 , C08G77/46 , C08G77/382 , C08G77/12
Abstract: This disclosure relates to polymerizable silicone compositions, methods for polymerizing such compositions, and to polymerized silicone compositions formed thereby. In one embodiment, a polymerizable composition includes one or more first organosiloxanes or organosilanes, each comprising a plurality of silicon hydride functional groups, one or more second organosiloxanes or organosilanes, each comprising a plurality of reactive heterocycloalkyl functional groups; and one or more third organosiloxanes or organosilanes, each comprising at least about one silicon hydride functional group and at least about one reactive heterocycloalkyl functional group; one or more reactive organic compounds, each comprising at least about one reactive heterocycloalkyl functional group; and an effective amount of a borane catalyst, present, for example, in an amount within the range of 0.0005 wt % to about 10 wt %, wherein the ratio of reactive heterocycloalkyl functional groups to reactive silicon hydride functional groups in the composition is in the range of 1:5 to 5:1.
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公开(公告)号:US20210094253A1
公开(公告)日:2021-04-01
申请号:US17032891
申请日:2020-09-25
Inventor: Kevin M. McCauley , Michael J. Tzivanis , Charles S. Golub , Mark F. Colton , Lily Lei , Gerald H. Ling , James Ludlow
Abstract: A multilayer tube includes an inner layer including a crosslinked fluoroelastomer rubber; and an outer layer including a crosslinked non-fluoroelastomer rubber, wherein the multilayer tube has a shore A hardness of about 40 to about 90.
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