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公开(公告)号：US07378101B2
公开(公告)日：2008-05-27
申请号：US10851965
申请日：2004-05-21
Applicant: John Morgan Hardham , Kendall Wayne King , Rajendra Krishnan , Kimberly Jean Dreier , David Ross McGavin , John David Haworth
Inventor： John Morgan Hardham , Kendall Wayne King , Rajendra Krishnan , Kimberly Jean Dreier , David Ross McGavin , John David Haworth
CPC classification number: A61K39/0216 , A61K39/0208 , A61K39/12 , A61K39/155 , A61K39/175 , A61K39/215 , A61K39/23 , A61K39/235 , A61K2039/521 , A61K2039/552 , A61K2039/55572 , A61K2039/55577 , A61K2039/70 , C07K14/195 , C12N2710/10034 , C12N2750/14034 , C12N2760/18434 , C12N2760/18634 , C12N2770/16034
Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.
Abstract translation: 本发明涉及通过其16S rRNA DNA鉴定的新的细菌分离物，其引起伴侣动物中的牙周病，其中包含的多核苷酸序列，由该多核苷酸序列编码的多肽和包含此类细菌，多核苷酸或多肽的疫苗。 还提供了用于治疗和预防牙周病的方法和用于检测和治疗牙周病试剂盒的试剂盒，用于检测和预防牙周病。 另外，提供了用于评估疫苗针对动物牙周病的功效的方法。
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公开(公告)号：US20050010032A1
公开(公告)日：2005-01-13
申请号：US10851965
申请日：2004-05-21
Applicant: John Hardham , Kendall King , Rajendra Krishnan , Kimberly Dreier , David McGavin , John Haworth
Inventor： John Hardham , Kendall King , Rajendra Krishnan , Kimberly Dreier , David McGavin , John Haworth
IPC: A61K39/02 , A61K39/155 , A61K39/175 , A61K39/215 , A61K39/23 , A61K39/235 , A61K39/295 , C07K14/195 , C12N1/21 , C07K17/00 , A01N43/04 , A61K31/715 , C07K1/00 , C07K14/00
CPC classification number: A61K39/0216 , A61K39/0208 , A61K39/12 , A61K39/155 , A61K39/175 , A61K39/215 , A61K39/23 , A61K39/235 , A61K2039/521 , A61K2039/552 , A61K2039/55572 , A61K2039/55577 , A61K2039/70 , C07K14/195 , C12N2710/10034 , C12N2750/14034 , C12N2760/18434 , C12N2760/18634 , C12N2770/16034
Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.
Abstract translation: 本发明涉及通过其16S rRNA DNA鉴定的新的细菌分离物，其引起伴侣动物中的牙周病，其中包含的多核苷酸序列，由该多核苷酸序列编码的多肽和包含此类细菌，多核苷酸或多肽的疫苗。 还提供了用于治疗和预防牙周病的方法和用于检测和治疗牙周病试剂盒的试剂盒，用于检测和预防牙周病。 另外，提供了用于评估疫苗针对动物牙周病的功效的方法。
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公开(公告)号：US12097255B2
公开(公告)日：2024-09-24
申请号：US17298070
申请日：2019-11-15
Inventor： Jae-Young Song , In-Ohk Ouh , Soodong Cho , Yongjik Lee , Ju-Yeon Lee , In-Soo Cho
IPC: A61K39/00 , A61K39/23 , C12N15/85 , G01N33/569 , G01N33/68
CPC classification number: A61K39/23 , C12N15/8509 , G01N33/56983 , G01N33/6854 , A61K2039/552 , C12N2015/8518 , C12N2750/14034 , G01N2333/015 , G01N2469/20
Abstract: The present invention provides: a recombinant expression vector comprising a gene encoding a porcine parvovirus VP2 protein; a recombinant plant or a recombinant insect cell transformed with the vector; and a vaccine composition for a porcine parvovirus and a composition for diagnosing porcine parvovirus, both of which contain a porcine parvovirus VP2 protein obtained from the recombinant plant or the recombinant insect cell. When the recombinant plant or recombinant insect cell of the present invention is used, the porcine parvovirus antigenic protein can be produced with high efficiency, and the porcine parvovirus antigenic protein production method using the recombinant plant or recombinant insect cell has excellent safety and stability compared with other antigen production methods.
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公开(公告)号：US20240226264A1
公开(公告)日：2024-07-11
申请号：US18396787
申请日：2023-12-27
Inventor： Arun IYER , Luis Alejandro Hernandez , Abby Patterson , Bailey Arruda , Luis Gabriel Gimenez-Lirola , Dave Michael Anstrom , Eric M. Vaughn , Pablo E Pineyro Pineiro , Troy James Kaiser , Joseph Ralph Hermann
CPC classification number: A61K39/12 , A61K39/23 , A61P31/20 , A61P37/04 , A61K2039/545 , A61K2039/552 , A61K2039/70 , C12N2750/10034 , C12N2750/10071 , C12N2750/14034
Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
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35.发明授权公开(公告)号：US11660337B2
公开(公告)日：2023-05-30
申请号：US17502116
申请日：2021-10-15
Inventor： Fengyan Li , Xiuwei Shu , Bo Wang , Yiping Wang , Wenyou Luo , Shenglei Chen , Yanxia Liu
IPC: A61K39/29 , A61K39/23 , A61K39/175 , A61K39/00
CPC classification number: A61K39/29 , A61K39/175 , A61K39/23 , A61K2039/552 , C12N2710/10334 , C12N2750/14034 , C12N2760/18434
Abstract: The present invention discloses a combination of vaccine strains for treating, preventing, relieving or controlling Canine Distemper, Canine Parvovirus Enteritis and Canine Infectious Hepatitis, comprising: Canine Distemper virus vaccine strain with the microorganism deposition accession number CGMCC No. 19397, Canine Parvovirus vaccine strain with the microorganism deposition accession number CGMCC No. 19398 and Canine Infectious Hepatitis virus vaccine strain with the microorganism deposition accession number CGMCC No. 19396. The three vaccine strains of the combination of vaccine strains are low in toxicity and good in immunogenicity. The present invention further discloses a live vaccine composition using the above-mentioned combination of vaccine strains as immunogen. The vaccine composition is safe and effective.
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Patent Agency Ranking
公开(公告)号：US09919047B2
公开(公告)日：2018-03-20
申请号：US13978113
申请日：2012-01-04
Applicant: David Kirn , John Bell , Caroline Breitbach , Anne Moon , Tae-Ho Hwang , Yu Kyoung Lee , Mi-kyung Kim
Inventor： David Kirn , John Bell , Caroline Breitbach , Anne Moon , Tae-Ho Hwang , Yu Kyoung Lee , Mi-kyung Kim
IPC: C07K16/00 , A61K39/285 , A61K39/00 , C07K16/30 , A61K35/76 , A61K35/761 , A61K35/763 , A61K35/768 , A61K35/26 , A61K39/12 , A61K39/125 , A61K39/145 , A61K39/165 , A61K39/17 , A61K39/205 , A61K39/235 , A61K39/245 , A61K39/395 , A61K45/06 , C07K16/18 , C12N7/00 , G01N33/574
CPC classification number: A61K39/285 , A61K35/26 , A61K35/76 , A61K35/761 , A61K35/763 , A61K35/768 , A61K39/0011 , A61K39/12 , A61K39/125 , A61K39/145 , A61K39/165 , A61K39/17 , A61K39/205 , A61K39/235 , A61K39/245 , A61K39/395 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/55522 , C07K16/18 , C07K16/30 , C07K2317/14 , C07K2317/734 , C12N7/00 , C12N2710/10034 , C12N2710/16632 , C12N2710/16634 , C12N2710/24034 , C12N2710/24132 , C12N2720/12232 , C12N2750/14034 , C12N2760/16034 , C12N2760/18134 , C12N2760/18434 , C12N2760/18734 , C12N2760/20034 , C12N2760/20232 , C12N2770/32034 , C12N2770/32334 , C12N2770/36034 , G01N33/574
Abstract: The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.
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公开(公告)号：US09314519B2
公开(公告)日：2016-04-19
申请号：US13967847
申请日：2013-08-15
Applicant: Intervet Inc.
Inventor： Zhisong Qiao , Kevin O'Connell
IPC: A61K47/42 , A61K39/155 , A61K39/175 , A61K47/10 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/26 , A61K39/23 , A61K39/235 , A61K39/145 , A61K39/12 , A61K9/08 , A61K39/02 , C12N7/00 , A61K39/00
CPC classification number: A61K39/235 , A61K9/08 , A61K39/0225 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/175 , A61K39/23 , A61K47/10 , A61K47/183 , A61K47/20 , A61K47/22 , A61K47/26 , A61K47/42 , A61K2039/521 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2710/10034 , C12N2750/14034 , C12N2750/14322 , C12N2760/18034 , C12N2760/18434 , C12N2760/18634
Abstract: The present invention discloses liquid stable vaccines that comprise a live attenuated virus, 10-30% sugar additive, and an amino acid. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines.
Abstract translation: 本发明公开了包含活减毒病毒，10-30％糖添加剂和氨基酸的液体稳定疫苗。 本发明还公开了通过这种疫苗的施用来制备这种疫苗和保护动物的方法。
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公开(公告)号：US20150246114A1
公开(公告)日：2015-09-03
申请号：US14422846
申请日：2013-08-16
Applicant: Intervet Inc.
Inventor： Zhisong Qiao , Kevin O'Connell
IPC: A61K39/235 , A61K39/155 , A61K39/23 , A61K39/02 , A61K9/08 , A61K47/42 , A61K47/10 , A61K47/18 , A61K47/26 , A61K39/175 , C12N7/00
CPC classification number: A61K39/235 , A61K9/08 , A61K39/0225 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/175 , A61K39/23 , A61K47/10 , A61K47/183 , A61K47/20 , A61K47/22 , A61K47/26 , A61K47/42 , A61K2039/521 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2710/10034 , C12N2750/14034 , C12N2750/14322 , C12N2760/18034 , C12N2760/18434 , C12N2760/18634
Abstract: The present invention discloses liquid stable vaccines that comprise a live attenuated virus, 10-30% sugar additive, and an amino acid. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines.
Abstract translation: 本发明公开了包含活减毒病毒，10-30％糖添加剂和氨基酸的液体稳定疫苗。 本发明还公开了通过这种疫苗的施用来制备这种疫苗和保护动物的方法。
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公开(公告)号：US20150246113A1
公开(公告)日：2015-09-03
申请号：US14713700
申请日：2015-05-15
Applicant: Boehringer Ingelheim Vetmedica, Inc.
Inventor： Arun V. IYER , Dianna M. Murphy JORDAN , Abby Rae PATTERSON , Michael B. ROOF , Eric Martin VAUGHN , Joseph Gilbert VICTORIA , Callie Ann VISEK
CPC classification number: A61K39/23 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , C07K14/005 , C12N7/00 , C12N2750/14021 , C12N2750/14022 , C12N2750/14034 , G01N33/6893
Abstract: The present invention provides novel nucleotides sequences, protein sequences, immunogenic compositions, vaccines, and methods that relate to making and using new porcine parvovirus 5A (PPV5A) that infects, inter alia, domestic swine. The compositions and methods provide for the detection of infections by said new virus, monitoring genetic changes in the viral sequences in wild and domestic animals and herds, and making and using novel vaccines for protecting animals from infection by the virus.
Abstract translation: 本发明提供新颖的核苷酸序列，蛋白质序列，免疫原性组合物，疫苗以及涉及制造和使用感染尤其是家猪的新型猪细小病毒5A（PPV5A）的方法。 组合物和方法提供了用于检测所述新病毒的感染，监测野生和家畜和猪群中的病毒序列的遗传变化，以及制备和使用新型疫苗以保护动物免受病毒感染。
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公开(公告)号：US20150182619A1
公开(公告)日：2015-07-02
申请号：US14282702
申请日：2014-05-20
Applicant: Zoetis LLC
Inventor： Cassius McAllister Tucker , John David Haworth
IPC: A61K39/235 , A61K39/23 , C12N7/00 , A61K39/155 , A61K39/02 , A61K39/12 , A61K39/175
CPC classification number: A61K39/235 , A61K39/00 , A61K39/0225 , A61K39/099 , A61K39/12 , A61K39/155 , A61K39/175 , A61K39/23 , A61K2039/525 , A61K2039/5254 , A61K2039/542 , A61K2039/545 , A61K2039/552 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2710/10034 , C12N2710/10071 , C12N2710/10334 , C12N2750/14034 , C12N2750/14071 , C12N2750/14334 , C12N2760/18034 , C12N2760/18071 , C12N2760/18434 , C12N2760/18471 , C12N2770/20022
Abstract: This invention relates to a method of treating a dog for canine diseases comprising administering to the dog therapeutically effective amounts of a vaccine, wherein the vaccine comprises viral antigens, a bacterin, or both, and wherein the vaccine is administered subcutaneously or orally according to the schedules provided herein.
Abstract translation: 本发明涉及一种治疗狗疾病的方法，包括向狗施用治疗有效量的疫苗，其中所述疫苗包含病毒抗原，菌苗或两者，并且其中所述疫苗根据所述疫苗皮下或口服给药 这里提供的时间表。
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