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    Rapid Cooling of Body and/or Brain by Irrigating with a Cooling Liquid
    33.
    发明申请
    Rapid Cooling of Body and/or Brain by Irrigating with a Cooling Liquid 审中-公开
    通过用冷却液冲洗身体和/或脑部的快速冷却

    公开(公告)号：US20130116761A1

    公开(公告)日：2013-05-09

    申请号：US13674601

    申请日：2012-11-12

    申请人： NEUROSAVE, INC.

    发明人： Thomas Kreck

    IPC分类号： A61F7/12

    CPC分类号： A61F7/12 ,  A61F7/0053 ,  A61F2007/0002 ,  A61F2007/0006 ,  A61F2007/0056 ,  A61F2007/0063 ,  A61H35/008 ,  A61H2201/025 ,  A61M16/04 ,  A61M16/0409 ,  A61M16/0438 ,  A61M16/0459 ,  A61M16/0479 ,  A61M16/0486 ,  A61M19/00 ,  A61M2205/3606 ,  A61M2210/0618

    摘要： Methods and devices are disclosed for providing therapeutic hypothermia using irrigation of the aerodigestive tract with cooled liquids. The disclosed method provides much more rapid therapeutic cooling to lower temperatures than could previously be achieved, thereby improving clinical outcomes. Novel cooling liquids and cooling devices are disclosed for carrying out the method. An external turbulent flow of cooling liquid may also be applied to the exterior of the head to further promote heat exchange. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway/aerodigestive tract, and more generalized cooling by irrigating the esophagus and/or stomach.

    摘要翻译： 公开了用于通过用冷却的液体冲洗消化道提供治疗性低温的方法和装置。 所公开的方法提供比先前可以实现的更快的治疗冷却以降低温度，从而改善临床结果。 公开了新颖的冷却液和冷却装置用于实施该方法。 冷却液体的外部湍流也可以施加到头部的外部，以进一步促进热交换。 公开了用于在医院场合或现场进行治疗性低温的快速诱导和维持的装置的多个实施例，使得在显着组织损伤发生之前可以快速建立低温治疗。 还公开了通过冲洗上气道/呼吸消化道来靶向脑冷却的方法，以及通过冲洗食管和/或胃更广泛的冷却。

    System and method for manipulating a temperature of a patient
    35.
    发明授权
    System and method for manipulating a temperature of a patient 有权
    用于操纵患者体温的系统和方法

    公开(公告)号：US08361132B2

    公开(公告)日：2013-01-29

    申请号：US12651490

    申请日：2010-01-04

    申请人： Eliahu Arad

    发明人： Eliahu Arad

    IPC分类号： A61F7/00

    CPC分类号： A61F7/12 ,  A61F2007/0006 ,  A61F2007/0056 ,  A61F2007/0086

    摘要： A system for affecting a temperature of a patient, the system includes: a nose catheter that is adapted to be inserted into a nose upper channel and to receive a first fluid; and a temperature control and fluid supply unit that is adapted to supply the first fluid and control a temperature of the first fluid so as to affect a temperature of a brain of a patient when the nose catheter is inserted into the nose upper channel of a patient and receives the first fluid.

    摘要翻译： 一种用于影响患者体温的系统，所述系统包括：鼻导管，其适于插入鼻上通道并接收第一流体; 以及温度控制和流体供应单元，其适于提供第一流体并控制第一流体的温度，以便当鼻导管插入患者的鼻上通道时影响患者的脑的温度 并接收第一流体。

    COOLING OF LOCALIZED AREAS OF THE BODY FOR CEREBRAL BLOOD FLOW AUGMENTATION
    36.
    发明申请
    COOLING OF LOCALIZED AREAS OF THE BODY FOR CEREBRAL BLOOD FLOW AUGMENTATION 审中-公开
    本地化局部地区冷冻血液循环系统

    公开(公告)号：US20120158105A1

    公开(公告)日：2012-06-21

    申请号：US13331977

    申请日：2011-12-20

    申请人： Denise Barbut ,  Wanchung Tang

    发明人： Denise Barbut ,  Wanchung Tang

    IPC分类号： A61F7/12 ,  A61F7/00

    CPC分类号： A61F7/12 ,  A61F7/00 ,  A61F2007/0006 ,  A61F2007/0017 ,  A61F2007/003 ,  A61F2007/0036 ,  A61F2007/0037 ,  A61F2007/0045 ,  A61F2007/0046

    摘要： Methods are described for augmenting cerebral blood flow and altering sympathetic nerve firing and catecholamine release by cooling a part of the body. In particular localized cooling of the nose or mouth is used to augment cerebral blood flow and alter sympathetic nerve firing. By cooling a localized area such as nose or mouth, release of norepinephrine after an ischemic event is inhibited. The methods described may be applied to augment cerebral blood flow and alter catecholamine release, particularly in treatment of stroke, heart attack and transient ischemic event.

    摘要翻译： 描述了通过冷却身体的一部分来增强脑血流量和改变交感神经放电和儿茶酚胺释放的方法。 特别地，鼻或嘴的局部冷却用于增加脑血流量并改变交感神经发射。 通过冷却局部区域如鼻或口，在缺血事件之后释放去甲肾上腺素被抑制。 所描述的方法可以用于增加脑血流量和改变儿茶酚胺释放，特别是在中风，心脏病发作和短暂性脑缺血事件的治疗中。

    Cooling of localized areas of the body for cerebral blood flow augmentation
    37.
    发明授权
    Cooling of localized areas of the body for cerebral blood flow augmentation 有权
    冷却身体局部区域的脑血流量增加

    公开(公告)号：US08167923B2

    公开(公告)日：2012-05-01

    申请号：US12578135

    申请日：2009-10-13

    申请人： Denise Barbut ,  Wanchung Tang

    发明人： Denise Barbut ,  Wanchung Tang

    IPC分类号： A61F7/12

    CPC分类号： A61F7/12 ,  A61F7/00 ,  A61F2007/0006 ,  A61F2007/0017 ,  A61F2007/003 ,  A61F2007/0036 ,  A61F2007/0037 ,  A61F2007/0045 ,  A61F2007/0046

    摘要： Methods are described for augmenting cerebral blood flow and altering sympathetic nerve firing and catecholamine release by cooling a part of the body. In particular localized cooling of the nose or mouth is used to augment cerebral blood flow and alter sympathetic nerve firing. By cooling a localized area such as nose or mouth, release of norepinephrine after an ischemic event is inhibited. The methods described may be applied to augment cerebral blood flow and alter catecholamine release, particularly in treatment of stroke, heart attack and transient ischemic event.

    摘要翻译： 描述了通过冷却身体的一部分来增强脑血流量和改变交感神经放电和儿茶酚胺释放的方法。 特别地，鼻或嘴的局部冷却用于增加脑血流量并改变交感神经发射。 通过冷却局部区域如鼻或口，在缺血事件之后释放去甲肾上腺素被抑制。 所描述的方法可以用于增加脑血流量和改变儿茶酚胺释放，特别是在中风，心脏病发作和短暂性脑缺血事件的治疗中。

    Device, method and system for treatment of sinusitis
    38.
    发明申请
    Device, method and system for treatment of sinusitis 审中-公开
    用于治疗鼻窦炎的装置，方法和系统

    公开(公告)号：US20110307039A1

    公开(公告)日：2011-12-15

    申请号：US12802781

    申请日：2010-06-14

    申请人： Thomas H. Cornell

    发明人： Thomas H. Cornell

    IPC分类号： A61F7/12

    CPC分类号： A61F7/0085 ,  A61F2007/0006 ,  A61F2007/006

    摘要： A device, method and system for facilitating treatment of a sinusitis condition, including a heat source configured to deliver an output of heated air to the nasal passages of an individual, and a delivery component having a space through which the heated air output of the heat source may pass, the delivery component being configured for placement in the individual's nostrils. The system provides a heated air output source and one or more delivery components configured and sized to fit within the nostril of an individual, which may be used to deliver one or more courses of heated air to a user's sinuses through a nostril.

    摘要翻译： 一种用于促进治疗鼻窦炎病症的装置，方法和系统，包括被配置为将热空气的输出传送到个体的鼻通道的热源，以及具有空间的输送部件，热空气输出的热量 来源可以通过，传送部件被配置为放置在个体的鼻孔中。 该系统提供加热的空气输出源和一个或多个配置和尺寸以配合在个体的鼻孔内的递送部件，其可用于通过鼻孔将一个或多个加热空气流程递送到使用者的鼻窦。

    Nosebleed treatment apparatus and associated method
    39.
    发明申请
    Nosebleed treatment apparatus and associated method 失效
    鼻塞治疗仪及相关方法

    公开(公告)号：US20090299405A1

    公开(公告)日：2009-12-03

    申请号：US12454289

    申请日：2009-05-15

    申请人： Anne DeCrescenzo ,  Dominick DeCrescenzo

    发明人： Anne DeCrescenzo ,  Dominick DeCrescenzo

    IPC分类号： A61F7/00 ,  A61B17/00

    CPC分类号： A61F7/02 ,  A61B17/12 ,  A61B17/122 ,  A61B2017/12004 ,  A61F2007/0006 ,  A61F2007/0219 ,  A61F2007/0225 ,  A61F2007/108

    摘要： The nosebleed treatment apparatus features a pair of pliable mirror image nose pads comprising a first nose pad and a second nose pad. A gel pack is disposed within each nose pad. Each gel pack has a first side spaced apart from a second side. The first side is adjacent to an inner surface of the medial pad section. The second side is disposed within the lateral pad section. A smooth shouldered reinforcement member is disposed atop each nose pad. A U-shaped oblong tensing member connects the first nose pad to the second nose pad at each reinforcement member. The apparatus can be placed in a freezer or cooler for extended cool retention within the gel packs when removed. Upon removal, the apparatus is placed on a bleeding nose and remains until removed, so that a patient need not hold it in place.

    摘要翻译： 鼻出血处理装置具有一对柔软的镜像鼻垫，其包括第一鼻垫和第二鼻垫。 在每个鼻垫内设置凝胶包装。 每个凝胶包具有与第二侧间隔开的第一侧。 第一侧邻近内侧垫部分的内表面。 第二侧设置在横向垫部分内。 在每个鼻垫顶部设置有平滑的肩部加强构件。 U型长圆形张紧构件在每个加强构件处将第一鼻垫连接到第二鼻垫。 该装置可以放置在冷冻器或冷却器中，以在去除时在凝胶组件内延长冷藏。 移除后，将装置放置在出血的鼻子上，并保持直到移除，以便患者无需将其固定到位。

    Temperature-controllable device
    40.
    发明授权
    Temperature-controllable device 失效
    温度可控设备

    公开(公告)号：US07559907B2

    公开(公告)日：2009-07-14

    申请号：US11064546

    申请日：2005-02-23

    申请人： Benjamin J. Krempel ,  Eric C. Selvik ,  Eric J. Altman ,  Matt R. Buchter ,  Alfredo T. Del Rio ,  Robert T. Dennis ,  Mark V. Martin

    发明人： Benjamin J. Krempel ,  Eric C. Selvik ,  Eric J. Altman ,  Matt R. Buchter ,  Alfredo T. Del Rio ,  Robert T. Dennis ,  Mark V. Martin

    IPC分类号： A61F5/00

    CPC分类号： A61F7/02 ,  A61F7/103 ,  A61F13/122 ,  A61F13/124 ,  A61F13/126 ,  A61F2007/0006 ,  A61F2007/0056

    摘要： Described herein are temperature-controllable devices, and methods for using them. In some variations, the devices comprise a fluid passageway region, which is configured to allow a fluid to flow therethrough, and a splint. The splint may be moldable to at least a portion of a subject's anatomy, e.g., a nose. In other variations, the devices comprise a fluid passageway region configured to allow a fluid to flow therethrough, and an absorbent pad. In some variations, the devices comprise three layers, in which two of the layers form a fluid passageway region and the third layer forms a pocket or pouch. In this way, the pouch may be configured to receive at least one splint therein, e.g., in order to provide support to an injured area such as a nose. Methods for using the devices to treat an injured area are also described. Kits are also described.

    摘要翻译： 这里描述的是温度可控的装置，以及使用它们的方法。 在一些变型中，装置包括流体通道区域，其被配置为允许流体流过其中，以及夹板。 夹板可以成型为受试者的解剖结构（例如鼻子）的至少一部分。 在其他变型中，装置包括被配置为允许流体流过其中的流体通道区域和吸收垫。 在一些变型中，装置包括三层，其中两层形成流体通道区域，第三层形成袋或袋。 以这种方式，袋可被配置为在其中容纳至少一个夹板，例如为了向受伤区域（例如鼻子）提供支撑。 还描述了使用该装置来治疗受伤区域的方法。 还描述了套件。