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31.发明申请Biosensor Measurement Machine , Biosensor Measurement System and Biosensor Measurement Method 有权生物传感器测量机，生物传感器测量系统和生物传感器测量方法公开(公告)号：US20090152127A1
公开(公告)日：2009-06-18
申请号：US11992102
申请日：2006-09-08
申请人： Shingo Kaimori , Toshifumi Hosoya , Moriyasu Ichino , Takahiko Kitamura , Isao Karube , Masao Gotoh , Hideaki Nakamura , Tomoko Ishikawa
发明人： Shingo Kaimori , Toshifumi Hosoya , Moriyasu Ichino , Takahiko Kitamura , Isao Karube , Masao Gotoh , Hideaki Nakamura , Tomoko Ishikawa
IPC分类号： G01N27/327 , G01N27/26 , G01N27/04 , G01N27/416
CPC分类号： G01N27/3273
摘要： Provided are a biosensor chip measurement machine that can obtain accurate measurement results within a short period of time by employing only a tiny amount as a sample, and a measurement method therefor.A biosensor measurement machine 20 includes a power source 21, which is connected to a voltage regulator 22, a measurement instrument 23, and a controller 24 for supplying power. When a biosensor chip 1 is connected to the biosensor measurement machine 20 and a voltage is applied, the measurement instrument begins the measurement of a current value for a biosensor. When a measured current value or a measured charge value is greater than a reference value, the measurement is ended in accordance with an instruction issued by the controller 24, and when the value is smaller than the reference value, the measurement is continued in accordance with a controller instruction.
摘要翻译： 提供一种生物传感器芯片测量机，其可以通过仅使用微量作为样品而在短时间内获得准确的测量结果及其测量方法。 生物传感器测量机20包括连接到电压调节器22的电源21，测量仪器23和用于供电的控制器24。 当生物传感器芯片1连接到生物传感器测量机20并施加电压时，测量仪器开始测量生物传感器的当前值。 当测量的电流值或测量的电荷值大于参考值时，根据控制器24发出的指令结束测量，并且当该值小于参考值时，根据 控制器指令。
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公开(公告)号：US20090124876A1
公开(公告)日：2009-05-14
申请号：US11994010
申请日：2006-06-27
申请人： Hideaki Nakamura , Masao Gotoh , Isao Karube
发明人： Hideaki Nakamura , Masao Gotoh , Isao Karube
CPC分类号： A61B10/0045 , A61B5/150022 , A61B5/150099 , A61B5/150282 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B2562/0295
摘要： There is a needle integrated biosensor, including: a biosensor including at least two electrodes, and a puncture needle to collect a body fluid by piercing a skin of a person to be tested, the biosensor and the puncture needle being integrated, wherein the puncture needle is able to be kept hygienic without the need of a protective cover or the like for the puncture needle.There is a needle integrated biosensor, including: a biosensor including at least two electrodes, and a puncture needle to collect a body fluid by piercing a skin of a person to be tested, the biosensor and the puncture needle being integrated, wherein a soft material is attached to the front end of the puncture needle so that the front end of the puncture needle is protected.
摘要翻译： 针组合生物传感器包括：生物传感器，包括至少两个电极;以及穿刺针，用于通过刺穿待测试人员的皮肤来收集体液，所述生物传感器和穿刺针是一体的，其中所述穿刺针 能够保持卫生，而不需要用于穿刺针的保护罩等。 针组合式生物传感器包括：生物传感器，包括至少两个电极;以及穿刺针，用于通过刺穿待测试人的皮肤，生物传感器和穿刺针一体地收集体液，其中柔软材料 附着在穿刺针的前端，使得穿刺针的前端受到保护。
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公开(公告)号：US20090053105A1
公开(公告)日：2009-02-26
申请号：US11795893
申请日：2006-01-23
申请人： Toshifumi Hosoya , Shingo Kaimori , Moriyasu Ichino , Hideaki Nakamura , Masao Gotoh , Fumiyo Kurusu , Tomoko Ishikawa , Isao Karube
发明人： Toshifumi Hosoya , Shingo Kaimori , Moriyasu Ichino , Hideaki Nakamura , Masao Gotoh , Fumiyo Kurusu , Tomoko Ishikawa , Isao Karube
IPC分类号： B01J19/00
CPC分类号： G01N33/54373 , B01L3/502707 , B01L2300/0645 , B01L2300/0822 , B01L2300/168
摘要： There is provided a sensor chip including: a base plate; a cover layer; a hollow reaction portion provided between the base plate and the cover layer, in which a reaction is performed between a sample and a reagent applied thereinto; a sensing member constructed of an electrode which is exposed to the hollow reaction portion; and a sample inlet for conducting the sample to the hollow reaction portion, wherein entire portions of the base plate and the cover layer, which are located opposite to the sensing member provided with the hollow reaction portion, are made transparent. Otherwise, in the above-described sensor chip, a plate A having a groove A to which a reagent has been applied and a plate B having a groove B are stacked on each other in such a manner that the groove A is coupled with the groove B, so that the hollow reaction portion is formed; and an opening width of the groove B is larger than an opening width of the groove A at a portion of the groove B which is located opposite to a portion with the groove A, to which the reagent has been applied.
摘要翻译： 提供了一种传感器芯片，包括：基板; 覆盖层; 设置在基板和覆盖层之间的中空反应部分，其中在样品和施加于其之间的试剂之间进行反应; 由暴露于中空反应部分的电极构成的传感部件; 以及用于将样品导引到中空反应部分的样品入口，其中与设置有中空反应部分的感测构件相对的基板和覆盖层的整个部分被制成透明的。 另外，在上述传感器芯片中，将具有涂敷有试剂的槽A的板A和具有槽B的板B彼此堆叠，使得槽A与槽 B，形成中空反应部分; 并且槽B的开口宽度大于槽B的与已经施加有试剂的部分的与槽A相对的部分处的槽A的开口宽度。
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公开(公告)号：US20090020420A1
公开(公告)日：2009-01-22
申请号：US11921166
申请日：2006-10-16
申请人： Takahiko Kitamura , Toshifumi Hosoya , Shingo Kaimori , Moriyasu Ichino , Hideaki Nakamura , Isao Karube , Masao Gotoh , Tomoko Ishikawa
发明人： Takahiko Kitamura , Toshifumi Hosoya , Shingo Kaimori , Moriyasu Ichino , Hideaki Nakamura , Isao Karube , Masao Gotoh , Tomoko Ishikawa
IPC分类号： G01N27/327 , B05D5/00
CPC分类号： C12Q1/002
摘要： It is intended to provide a biosensor chip capable of rapid and correct measurement, including a reaction chamber that enables a measurement of a very small amount of a measurement sample and has a small capacity and potassium ferricyanide having a very small crystal particle size disposed in the reaction chamber.In a biosensor chip 1, electrodes 3 and 4 are disposed on the lower substrate 2, and lower spacer 5 (7 and 8) is adhered on the electrodes 3 and 4. An upper spacer 11 (12 and 13) is adhered to an upper substrate 15, and a lower spacer 5 is attached to the upper spacer 11 by and adhesive agent 10. A lower groove 9 is formed between long and short lower spacers 7 and 8, and an upper groove 14 is formed between long and short spacers 12 and 13, so that a reaction chamber 17 is formed by the upper and lower grooves 9 and 14. A capacity of the reaction chamber is 0.3 μL, and an enzyme 18 and potassium ferricyanide are disposed in the reaction chamber 17 in such a fashion as to oppose to each other with a gap being defined therebetween. A crystal particle diameter of the potassium ferricyanide is 100 μm or less, and amount of the potassium ferricyanide is V×0.1 mg or more when the capacity of the reaction chamber 17 is V.
摘要翻译： 旨在提供能够快速且正确测量的生物传感器芯片，其包括能够测量非常少量的测量样品并且具有小容量的反应室和具有非常小的晶粒度的铁氰化钾 反应室。 在生物传感器芯片1中，电极3和4设置在下基板2上，下隔片5（7和8）粘附在电极3和4上。上间隔件11（12和13） 基板15和下隔板5通过粘合剂10附接到上间隔件11.下槽9形成在长和短下隔板7和8之间，并且上槽14形成在长间隔件12和短间隔件12之间 和13，使得反应室17由上下槽9和14形成。反应室的容量为0.3微米，酶18和铁氰化钾以如下方式设置在反应室17中： 彼此相对，在其间限定间隙。 当反应室17的容量为V时，铁氰化钾的晶粒直径为100μm以下，铁氰化钾的量为Vx0.1mg以上。
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公开(公告)号：US20070183975A1
公开(公告)日：2007-08-09
申请号：US10554789
申请日：2004-04-30
CPC分类号： C12N9/12 , A61K38/164 , A61K38/1709 , C07K2319/00
摘要： A polypeptide absorbable into digestive organs, which is linked with a bioactive polypeptide, and assists absorption of the bioactive polypeptide into digestive organs when it is orally taken; a fusion polypeptide comprising the polypeptide absorbable into digestive organs and the bioactive polypeptide; and an oral composition comprising the fusion polypeptide are provided.
摘要翻译： 可吸收到消化器官中的多肽，其与生物活性多肽连接，并且当其被口服时有助于生物活性多肽吸收到消化器官中; 包含可吸收到消化器官和生物活性多肽中的多肽的融合多肽; 并提供包含融合多肽的口腔组合物。
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公开(公告)号：US20070000776A1
公开(公告)日：2007-01-04
申请号：US10565830
申请日：2004-04-15
申请人： Isao Karube , Masao Gotoh , Hideaki Nakamura
发明人： Isao Karube , Masao Gotoh , Hideaki Nakamura
IPC分类号： G01N33/487
CPC分类号： G01N27/3272
摘要： A downsized biosensor in which an electrode is formed on one sheet of electrically-insulated substrate, and a sheet of flat substrate is worked three-dimensionally so as to dispose the electrode on the inner side of the substrate to provide a two-dimensional or three-dimensional electrode disposition, whereby a sample introduced by capillary phenomenon can be measured quantitatively in a small space. A production method of a biosensor comprising the steps of bending a plate member so as to position an electrode formed on the surface of the electrically-insulated plane member on the inner side, and disposing the electrode in a space surrounded by a substrate and a cover to thereby form the substrate and the cover from one sheet of plate member.
摘要翻译： 在一片电绝缘基板上形成电极的小型生物传感器，三维地加工一层平面基板，以将电极设置在基板的内侧，以提供二维或三维 通过毛细管现象引入的样品可以在很小的空间内定量测量。 一种生物传感器的生产方法，包括以下步骤：弯曲板构件，以将形成在电绝缘平面构件的表面上的电极定位在内侧，并将电极设置在由基板和盖子 从而从一片板构件形成基板和盖。
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公开(公告)号：US06868812B2
公开(公告)日：2005-03-22
申请号：US09985798
申请日：2001-11-06
CPC分类号： F01L1/34 , F01L1/022 , F01L2820/041
摘要： A valve timing control system for an internal combustion engine has: a drive force transmitter or a chain sprocket; a cam shaft; a housing, a vane rotor; an advanced angle chamber and a delayed angle chamber; an oil pressure conveyer; a protrusion shaft; a target plate; and a sensor. The protrusion shaft is formed on at least one of the vane rotor and the housing, and protrudes forward. The target plate is mounted on at least one of the vane rotor and the housing. The target plate is formed substantially flat through a press molding, and is press fitted to the protrusion shaft. The target plate has a plurality of detector protrusions and one index protrusion. The detector protrusion and the index protrusion are equal in width.
摘要翻译： 用于内燃机的气门正时控制系统具有：驱动力传递器或链轮; 凸轮轴; 壳体，叶片转子; 前进角室和延迟角室; 油压输送机; 突出轴; 目标板; 和传感器。 突出轴形成在叶片转子和壳体中的至少一个上并向前突出。 目标板安装在叶片转子和壳体中的至少一个上。 目标板通过压制成型基本上平坦，并且被压配合到突出轴。 目标板具有多个检测器突起和一个索引突起。 检测器突出部和折痕突起的宽度相等。
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38.发明授权Actuating apparatus applicable to actuation of valve used for controlling engine idling revolution 失效适用于控制发动机怠速转速的阀的致动的致动装置
公开(公告)号：US5647321A
公开(公告)日：1997-07-15
申请号：US606281
申请日：1996-02-23
CPC分类号： H02K26/00
摘要： In an actuating apparatus applicable to an actuation of a valve installed in an intake air passage of an internal combustion engine, a first magnetic circuit (D.sub.1) is formed with a stationary member (A) and with a part of a driven member (B), the driven member being disposed within the stationary member so as to be linearly or angularly displaced, and a second magnetic circuit (D.sub.2) is formed in the stationary member and another part of the driven member so as to be branched from the first magnetic circuit, a strength of a magnetic flux flowing through the second magnetic circuit being the same as that of a magnetic flux flowing through the first magnetic circuit and a direction of the magnetic flux flowing through the second magnetic circuit being opposite to that of the magnetic flux flowing through the first magnetic circuit. Under the condition described above, at least one new magnetic flux is generated by means of electromagnetic coil(s), a direction of the new magnetic flux being such that the magnetic flux flowing through either of the first or second magnetic circuit is strengthened and that flowing through the other of the first or second magnetic circuit is weakened so that the driven member is linearly or angularly displaced at a position at which strengths of both magnetic fluxes flowing through the first and second magnetic circuits become again balanced.
摘要翻译： 在适用于安装在内燃机的进气通道中的阀的致动的致动装置中，第一磁路（D1）形成有固定构件（A）和被驱动构件（B）的一部分， 被驱动构件被设置在固定构件内以线性或角度位移，并且第二磁路（D2）形成在固定构件和从动构件的另一部分中以便从第一磁路分支 流过第二磁路的磁通量的强度与流过第一磁路的磁通的磁通强度和流过第二磁路的磁通方向与磁通流动相反的方向 通过第一磁路。 在上述条件下，通过电磁线圈产生至少一个新的磁通量，新磁通的方向使得流过第一或第二磁路中的任何一个的磁通增强，并且 流过第一或第二磁路中的另一个的电路被削弱，使得被驱动构件在流过第一和第二磁路的两个磁通量的强度再次平衡的位置处线性或角位移。
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公开(公告)号：US5376861A
公开(公告)日：1994-12-27
申请号：US860667
申请日：1992-03-30
申请人： Hideaki Nakamura , Eiji Karaki
发明人： Hideaki Nakamura , Eiji Karaki
CPC分类号： H03H9/02023 , H03H3/02 , H03H9/19
摘要： An AT-cut crystal oscillating reed formed by etching an AT-cut crystal wafer is provided. The wafer has a rotational parallel cut obtained by rotating a parallel cut by an angular degree of .theta..degree. relative to the X-axis of the wafer. The etching cross-section of the AT-cut crystal oscillating reed has a surface at an angle about 90.degree. from the front or back surface of the AT-cut crystal oscillating reed. This AT-cut crystal oscillating reed exhibits uniform characteristics and excellent reliability. Also provided is an AT-cut crystal oscillating reed with a low CI value. Finally, a method of etching an AT-cut crystal oscillating reed from an AT-cut crystal wafer is provided. A corrosion resisting film with gaps coats the wafer and is used in the etching process. In a preferred embodiment, the thickness of the wafer is designated t, the width of the gaps in the corrosion resisting films is designated l, and l.gtoreq.t/tan .theta.. The corrosion resisting film may be metal and may be formed into electrodes after the crystal oscillating reed is etched. In this manner, crystal oscillating reeds may be mass produced at a relatively low cost.
摘要翻译： 提供通过蚀刻AT切割晶片形成的AT切割晶体振荡簧片。 晶片具有通过使平行切割相对于晶片的X轴旋转角度θ°而获得的旋转平行切割。 AT切割晶体振荡簧片的蚀刻横截面具有与AT切割晶体振荡簧片的前表面或后表面成90°角的表面。 这种AT切割水晶摆动簧片具有均匀的特性和出色的可靠性。 还提供了具有低CI值的AT切割晶体振荡簧片。 最后，提供了从AT切割晶体晶片蚀刻AT切割晶体振荡簧片的方法。 具有间隙的耐腐蚀膜涂覆晶片并用于蚀刻工艺。 在优选实施例中，晶片的厚度指定为t，耐腐蚀膜中的间隙的宽度指定为l，并且l≥t/tanθ。 耐腐蚀膜可以是金属，并且可以在晶体振荡筘被蚀刻之后形成电极。 以这种方式，可以以相对较低的成本批量生产晶体振荡簧片。
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公开(公告)号：US08319383B2
公开(公告)日：2012-11-27
申请号：US12862711
申请日：2010-08-24
摘要： A brush assembly applied to a motor includes a body portion attachable to a lower case, and an external connection substrate formed by a flexible substrate. A pair of brush pieces protrude from a front end of the body portion so as to be in contact with brush slide portions of commutator segments. The external connection substrate has a pair of terminals exposed from a housing and capable of being connected to spring terminals of an apparatus by crimping. The terminals are provided at a rear end of the external connection substrate, and protrude from the housing in the radial direction. First connecting portions electrically connected to the brush pieces are provided at a rear end of the body portion, and a pair of right and left second connecting portions are provided at a front end of the external connection substrate.
摘要翻译： 应用于马达的刷子组件包括可附接到下壳体的主体部分和由柔性基板形成的外部连接基板。 一对刷片从本体部的前端突出，以与换向片的刷子滑动部分接触。 外部连接基板具有从外壳露出的一对端子，能够通过卷边与设备的弹簧端子连接。 端子设置在外部连接基板的后端，并且从壳体沿径向突出。 电连接到电刷片的第一连接部分设置在主体部分的后端，并且一对左右的第二连接部分设置在外部连接基板的前端。
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