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公开(公告)号:US12151002B2
公开(公告)日:2024-11-26
申请号:US15305510
申请日:2015-04-21
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Matthew Webber Getzin , Lars Arne Gjesteby , Wenxiang Cong
Abstract: Imaging systems and methods are provided. Systems and methods of the subject invention can include the use of nanoparticles (for example, nanophosphors) within a sample to be imaged. Excitation with radiation, such X-ray radiation, can be performed on the nanoparticles to give rise to a change in one or more resonance parameters of the nanoparticles, and this change can be measured using magnetic resonance imaging to provide localization information.
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公开(公告)号:US12000916B2
公开(公告)日:2024-06-04
申请号:US17279400
申请日:2019-03-13
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Lars Arne Gjesteby , Wenxiang Cong
CPC classification number: G01R33/481 , A61B6/037 , A61B6/4258 , A61B6/4417 , A61B6/5235 , G01R33/0385 , G01R33/38
Abstract: A simultaneous emission-transmission tomography in an MRI hardware framework is described. A method of multimodality imaging includes reconstructing, by a simultaneous emission transmission (SET) circuitry, a concentration image based, at least in part, on a plurality of selected γ-rays; and reconstructing, by the SET circuitry, an attenuation image based, at least in part, on the plurality of selected γ-rays. The plurality of selected γ-rays is emitted by a polarized radio tracer included in a test object. The selected γ-rays are selected based, at least in part, on a radio frequency (RF) pulse and based, at least in part, on a gradient magnetic field.
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33.
公开(公告)号:US11850081B2
公开(公告)日:2023-12-26
申请号:US17460470
申请日:2021-08-30
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong
IPC: G06T11/00 , A61B6/03 , G06N3/04 , G06V10/764 , G06V10/774 , G06V10/60
CPC classification number: A61B6/032 , G06N3/04 , G06T11/006 , G06V10/60 , G06V10/764 , G06V10/774 , G06T2207/10081 , G06T2207/20081 , G06T2207/20084
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening.
An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.-
公开(公告)号:US11638567B2
公开(公告)日:2023-05-02
申请号:US17679716
申请日:2022-02-24
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Lars Arne Gjesteby
IPC: A61B6/00 , A61B5/055 , G01R33/381 , G01R33/383 , G01R33/48 , A61B5/00 , A61B6/02 , A61B6/03
Abstract: Systems and methods for obtaining simultaneous X-ray—magnetic resonance imaging (MRI) images are provided. A magnetic resonance X-ray CT (MRX) system can combine X-ray imaging and MRI in a cost-effective and relatively simple solution for improved imaging. During imaging of a subject, the X-ray source and X-ray detector can be simultaneously rotated around the subject, and the means for generating a magnetic field can also be rotated around the subject. The means for generating a magnetic field can be a plurality of permanent magnets.
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公开(公告)号:US20230035618A1
公开(公告)日:2023-02-02
申请号:US17896279
申请日:2022-08-26
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Ruibin Feng , David Rundle
Abstract: A neural network based corrector for photon counting detectors is described. A method for photon count correction includes receiving, by a trained artificial neural network (ANN), a detected photon count from a photon counting detector. The detected photon count corresponds to an attenuated energy spectrum. The attenuated energy spectrum is related to characteristics of an imaging object and is based, at least in part, on an incident energy spectrum. The method further includes correcting, by the trained ANN, the detected photon count to produce a corrected photon count. The method may include reconstructing, by image reconstruction circuitry, an image based, at least in part, on the corrected photon count.
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公开(公告)号:US11448778B2
公开(公告)日:2022-09-20
申请号:US16770675
申请日:2018-12-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Ruibin Feng , David Rundle
Abstract: A neural network based corrector for photon counting detectors is described. A method for photon count correction includes receiving, by a trained artificial neural network (ANN), a detected photon count from a photon counting detector. The detected photon count corresponds to an attenuated energy spectrum. The attenuated energy spectrum is related to characteristics of an imaging object and is based, at least in part, on an incident energy spectrum. The method further includes correcting, by the trained ANN, the detected photon count to produce a corrected photon count. The method may include reconstructing, by image reconstruction circuitry, an image based, at least in part, on the corrected photon count.
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37.
公开(公告)号:US11232541B2
公开(公告)日:2022-01-25
申请号:US16594567
申请日:2019-10-07
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Chenyu You , Wenxiang Cong , Hongming Shan , Guang Li
Abstract: A system for generating a high resolution (HR) computed tomography (CT) image from a low resolution (LR) CT image is described. The system includes a first generative adversarial network (GAN) and a second GAN. The first GAN includes a first generative neural network (G) configured to receive a training LR image dataset and to generate a corresponding estimated HR image dataset, and a first discriminative neural network (DY) configured to compare a training HR image dataset and the estimated HR image dataset. The second GAN includes a second generative neural network (F) configured to receive the training HR image dataset and to generate a corresponding estimated LR image dataset, and a second discriminative neural network (DX) configured to compare the training LR image dataset and the estimated LR image dataset. The system further includes an optimization module configured to determine an optimization function based, at least in part, on at least one of the estimated HR image dataset and/or the estimated LR image dataset. The optimization function contains at least one loss function. The optimization module is further configured to adjust a plurality of neural network parameters associated with at least one of the first GAN and/or the second GAN, to optimize the optimization function.
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公开(公告)号:US20210389399A1
公开(公告)日:2021-12-16
申请号:US17279400
申请日:2019-03-13
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Lars Arne Gjesteby , Wenxiang Cong
Abstract: A simultaneous emission-transmission tomography in an MRI hardware framework is described. A method of multimodality imaging includes reconstructing, by a simultaneous emission transmission (SET) circuitry, a concentration image based, at least in part, on a plurality of selected γ-rays; and reconstructing, by the SET circuitry, an attenuation image based, at least in part, on the plurality of selected γ-rays. The plurality of selected γ-rays is emitted by a polarized radio tracer included in a test object. The selected γ-rays are selected based, at least in part, on a radio frequency (RF) pulse and based, at least in part, on a gradient magnetic field.
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公开(公告)号:US20210374961A1
公开(公告)日:2021-12-02
申请号:US17404361
申请日:2021-08-17
Applicant: Rensselaer Polytechnic Institute
Inventor: Ge Wang , Lars Arne Gjesteby , Hongming Shan
Abstract: Training a CNN with pseudo ground truth for CT artifact reduction is described. An estimated ground truth apparatus is configured to generate an estimated ground truth image based, at least in part, on an initial CT image that includes an artifact. Feature addition circuitry is configured to add a respective feature to each of a number, N, copies of the estimated ground truth image to create the number, N, initial training images. A computed tomography (CT) simulation circuitry is configured to generate a plurality of simulated training CT images based, at least in part, on at least some of the N initial training images. An artifact reduction circuitry is configured to generate a plurality of input training CT images based, at least in part, on the simulated training CT images. A CNN training circuitry is configured to train the CNN based, at least in part, on the input training CT images and based, at least in part, on the initial training images.
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40.
公开(公告)号:US11127175B2
公开(公告)日:2021-09-21
申请号:US16647220
申请日:2018-09-26
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor: Ge Wang , Wenxiang Cong
Abstract: A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
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