公开(公告)号：US20160070066A1

公开(公告)日：2016-03-10

申请号：US14853078

申请日：2015-09-14

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Desmond Adler

IPC: G02B6/28 ,  G01B9/02

CPC classification number: G02B6/2861 ,  G01B9/02004 ,  G01B9/02091 ,  G02B6/2808 ,  G02B6/3502

Abstract: In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the first optical coupler and a second end in optical communication with a second mirror, wherein light entering the first arm of the first optical coupler leaves the first arm of the first optical coupler either delayed by an amount (τ) or substantially undelayed.

Abstract translation: 在一个实施例中，本发明涉及一种用于增加光源中的重复率的装置。 该装置包括：第一光耦合器，包括第一臂，第二臂和第三臂; 与第一光耦合器的第二臂光学通信的第一反射镜; 以及第一光学延迟线，其具有与第一光耦合器的第三臂光学通信的第一端和与第二反射镜光学连通的第二端，其中进入第一光耦合器的第一臂的光离开第一臂的第一臂 第一光耦合器延迟量（τ）或基本上不延迟。

公开(公告)号：US12274532B2

公开(公告)日：2025-04-15

申请号：US17507259

申请日：2021-10-21

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

公开(公告)号：US12138017B2

公开(公告)日：2024-11-12

申请号：US17508502

申请日：2021-10-22

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

公开(公告)号：US12121325B2

公开(公告)日：2024-10-22

申请号：US17508272

申请日：2021-10-22

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

CPC classification number: A61B5/02007 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/0084

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

公开(公告)号：US20230075598A1

公开(公告)日：2023-03-09

申请号：US17980323

申请日：2022-11-03

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

公开(公告)号：US20180192957A1

公开(公告)日：2018-07-12

申请号：US15913300

申请日：2018-03-06

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Chenyang Xu

IPC: A61B5/00

CPC classification number: A61B5/6852 ,  A61B5/0066 ,  A61B5/7264

Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

公开(公告)号：US10006753B2

公开(公告)日：2018-06-26

申请号：US14573749

申请日：2014-12-17

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Victor Grinberg

IPC: H04B10/61 ,  G01B9/02 ,  H03G3/30 ,  H04B10/67

CPC classification number: G01B9/02055 ,  G01B9/02004 ,  G01B9/02044 ,  G01B9/02074 ,  G01B9/02083 ,  H03G3/3084 ,  H04B10/616 ,  H04B10/671

Abstract: In part, aspects of the invention relate to methods, apparatus, and systems for intensity and/or pattern line noise reduction in a data collection system such as an optical coherence tomography system that uses an electromagnetic radiation source and interferometric principles. In one embodiment, the noise is intensity noise or line pattern noise and the source is a laser such as a swept laser. One or more attenuators responsive to one or more control signals can be used in conjunction with an analog or digital feedback network in one embodiment.

公开(公告)号：US20180003482A1

公开(公告)日：2018-01-04

申请号：US15644668

申请日：2017-07-07

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt

IPC: G01B9/02 ,  A61B5/00 ,  H01S5/50 ,  H01S5/14 ,  H01S3/106

CPC classification number: G01B9/02091 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02069 ,  G01B2290/25 ,  G01B2290/60 ,  H01S3/1062 ,  H01S5/141 ,  H01S5/146 ,  H01S5/5036

Abstract: In one embodiment of the invention, a semiconductor optical amplifier (SOA) in a laser ring is chosen to provide low polarization-dependent gain (PDG) and a booster semiconductor optical amplifier, outside of the ring, is chosen to provide high polarization-dependent gain. The use of a semiconductor optical amplifier with low polarization-dependent gain nearly eliminates variations in the polarization state of the light at the output of the laser, but does not eliminate the intra-sweep variations in the polarization state at the output of the laser, which can degrade the performance of the SS-OCT system.

公开(公告)号：US20150297373A1

公开(公告)日：2015-10-22

申请号：US14115527

申请日：2013-03-12

Applicant: Lightlab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Hiram Bezzerra ,  Christopher Petroff ,  Ajay Gopinath

IPC: A61F2/86

CPC classification number: A61F2/86 ,  A61B5/0066 ,  A61B5/02007 ,  A61B5/1076 ,  A61B2090/061 ,  A61F2/82 ,  A61F2230/0069 ,  A61F2240/001 ,  A61F2250/006 ,  G06F19/321

Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.

Abstract translation: 部分地，本发明涉及一种用于定位用于放置在容器中的支架的尺寸的方法。 在一个实施例中，该方法包括以下步骤：将容器分成多个段，每个段被定义为容器的分支之间的空间; 选择似乎没有疾病的起点; 此时将直径定义为最大直径; 根据幂律计算下一相邻段的最大直径; 测量下一个相邻段的实际直径; 选择计算的最大直径或测量的最大直径取决于哪个直径较大; 使用所选择的最大直径来找到该下一段的最大直径; 反复进行，直到检查船舶的整个长度; 以及响应于末端近端和远端段的直径选择支架。