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31.
公开(公告)号:US20140046031A1
公开(公告)日:2014-02-13
申请号:US13968942
申请日:2013-08-16
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill M. Giles-Komar , Jinquan Luo , Michael A. Rycyzyn , Raymond Sweet
IPC: C07K16/24
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 抗IL-23p19抗体,包括编码至少一种抗IL-23p19抗体的分离的核酸,载体,宿主细胞,转基因动物或植物及其制备和使用的方法具有在诊断和/或治疗组合物中的应用 ,方法和设备。
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公开(公告)号:US20240199733A1
公开(公告)日:2024-06-20
申请号:US18444595
申请日:2024-02-16
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Pauchenberger , Raymond Sweet
CPC classification number: C07K16/244 , A61K9/0019 , A61K9/08 , A61K39/3955 , A61K47/26 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C07K2319/30
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US20240141055A1
公开(公告)日:2024-05-02
申请号:US18216074
申请日:2023-06-29
Applicant: Janssen Biotech, Inc
Inventor: John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
IPC: C07K16/28
CPC classification number: C07K16/2878 , C07K16/2896 , A61K2039/505
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号:US11939375B2
公开(公告)日:2024-03-26
申请号:US17181778
申请日:2021-02-22
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Rauchenberger , Raymond Sweet
CPC classification number: C07K16/244 , A61K9/0019 , A61K9/08 , A61K39/3955 , A61K47/26 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C07K2319/30
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US20210188966A1
公开(公告)日:2021-06-24
申请号:US17181778
申请日:2021-02-22
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Rauchenberger , Raymond Sweet
IPC: C07K16/24 , A61K9/00 , A61K9/08 , A61K39/395 , A61K47/26
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US10954297B2
公开(公告)日:2021-03-23
申请号:US16013141
申请日:2018-06-20
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Rauchenberger , Raymond Sweet
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US10576150B2
公开(公告)日:2020-03-03
申请号:US16358775
申请日:2019-03-20
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , G01N33/68 , C07K16/24 , A61K45/06 , A61K39/00
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US20190248910A1
公开(公告)日:2019-08-15
申请号:US16382645
申请日:2019-04-12
Applicant: Janssen Biotech, Inc
Inventor: John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
IPC: C07K16/28
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号:US20190201527A1
公开(公告)日:2019-07-04
申请号:US16358775
申请日:2019-03-20
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , C07K16/24 , A61K45/06 , G01N33/68
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号:US20180291096A1
公开(公告)日:2018-10-11
申请号:US16013141
申请日:2018-06-20
Applicant: Janssen Biotech, Inc.
Inventor: Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Rauchenberger , Raymond Sweet
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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