公开(公告)号：US20140293224A1

公开(公告)日：2014-10-02

申请号：US14302793

申请日：2014-06-12

Applicant: Bioptigen, Inc.

Inventor： Eric L. Buckland ,  Nestor O. Farmiga ,  Robert H. Hart ,  Andrew Murnan ,  Christopher Saxer

IPC: A61B3/10 ,  G01B9/02

CPC classification number: A61B3/102 ,  A61B3/13 ,  A61B3/132 ,  A61B5/0066 ,  G01B9/02039 ,  G01B9/02091 ,  G02B1/11 ,  G02B21/0012 ,  G02B21/0048 ,  G02B21/006 ,  G02B21/02 ,  G02B21/025 ,  G02B27/0031 ,  G02B27/0955 ,  G02B27/141

Abstract: Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam.

Abstract translation: 本发明构思的一些实施例提供了用于与显微镜集成的光学相干断层摄影（OCT）系统。 OCT系统包括耦合到显微镜的成像路径的样品臂。 所述采样臂包括输入光束变焦组件，其包括至少两个可移动透镜，所述可移动透镜被配置为提供OCT信号光束的形状控制 扫描组件，其包括至少一个扫描镜并被配置为用于远心扫描所述OCT信号光束; 以及光束扩展器，其被配置为设置入射在显微镜物镜上的OCT信号光束直径。 形状控制包括成像OCT束的数值孔​​径和焦点位置的可分离控制。