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公开(公告)号：US11172731B2
公开(公告)日：2021-11-16
申请号：US16464443
申请日：2017-11-28
申请人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , THE UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH
摘要： Dual-layer insole apparatuses for diabetic foot lesion prevention and related methods are provided. Some insole apparatuses have a body defining a plurality of cavities configured to be coupled to a fluid source. The fluid source can deliver fluid to vary internal pressures of the cavities. The body further defines an insole-shaped structure.
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公开(公告)号：US20210341494A1
公开(公告)日：2021-11-04
申请号：US17361763
申请日：2021-06-29
发明人： Sid E. O'Bryant , Leigh A. Johnson
摘要： The present invention includes methods for selecting a therapy for improved cognition as well as prevention of cognitive loss/dysfunction using one or more endophenotypes comprising: obtaining a sample from a subject; measuring biomarkers that differentiate between an inflammatory, a metabolic, a neurotrophic, and a depressive endophenotype; and selecting a course of treatment for the subject based on whether the subject is scored as having a high or a low endophenotype for one or more of the inflammatory, a metabolic, a neurotrophic, and a depressive endophenotypes.
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公开(公告)号：US20210230862A1
公开(公告)日：2021-07-29
申请号：US16774936
申请日：2020-01-28
发明人： Sheldon Q. SHI , Weihuan ZHAO , Liping CAI
摘要： A method of making an insulated material comprises melting a phase change material to form liquid phase change material, combining the liquid phase change material with an insulating material, and forming a composite insulation material in response to the combining. The insulating material can be a porous material that comprises a plurality of pores, and the liquid phase change material is disposed in the plurality of pores. The phase change material can also be stored in a container and used as layer in an insulation system.
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公开(公告)号：US20210116390A1
公开(公告)日：2021-04-22
申请号：US17073601
申请日：2020-10-19
IPC分类号： G01N21/95 , G01N21/27 , G01N21/3563
摘要： The present disclosure provides an extended spectroscopic wafer characterization metrology that provides highly sensitive chemical bonding transformation information in the extended mid-IR region (e.g., 1 μm-25 μm). The extended spectroscopic metrology described herein utilizes both total internal reflection and transmission infrared spectroscopy with angle dependent spectroscopic acquisition to optimize high detection sensitivity for the measurement of fundamental chemical bonding vibrations and associated rotational-vibrational structure for fabricated film stacks and nanostructures on a wafer substrate that has been polished on the both sides.
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公开(公告)号：US20210069379A1
公开(公告)日：2021-03-11
申请号：US17015246
申请日：2020-09-09
发明人： DIANA BERMAN , DONGHUI ZHU , OLGA SHENDEROVA
摘要： A new insight on the lubrication of artificial joint components is presented. Addition of small amounts of nanoscale diamond particles to an artificial joint promotes a substantial improvement in friction and wear behavior of the artificial joint surfaces. Artificial joint implants are made from a variety of materials ranging from metal alloys to polymers. Suitable methods of applying nanoscale diamond particles to an artificial joint include (i) coating an effective amount of nanoscale diamond particles onto the artificial joint prior to implants; (ii) applying a composition to the artificial joint during an artificial joint implanting surgery, wherein said composition comprises a biocompatible carrier fluid and an effective amount of nanoscale diamond particles dispersed in the biocompatible carrier fluid; (iii) injecting the composition for lubricating the artificial joint into the artificial joint.
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36.发明申请公开(公告)号：US20210010056A1
公开(公告)日：2021-01-14
申请号：US16923986
申请日：2020-07-08
发明人： Xiaoqiang WANG
摘要： In alternative embodiments, provided are methods for the glycosylation modification of bioactive compounds and drugs using isolated, recombinant or genetically modified uridine diphosphate glycosyl-transferases (UGTs). In alternative embodiments, provided are methods for modifying UGTs to generate recombinant UGTs with altered donor and/or acceptor specificities. In alternative embodiments, provided are methods for screening for recombinantly engineered UGTs with new or altered properties, for example, for new or altered donor and/or acceptor specificities, where in alternative embodiments the screening comprise use of bacterial, yeast or baculovirus expression system.
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公开(公告)号：US20210008658A1
公开(公告)日：2021-01-14
申请号：US16926194
申请日：2020-07-10
发明人： Michael FRANK , Tianhao WANG , Rajiv MISHRA
IPC分类号： B23K20/12
摘要： A friction stir welding tool comprises a cylindrical shank, a shoulder portion disposed at a distal end of the shank, a pin extending from the shoulder, a cutting insert mounted within a concave portion at the distal end of the shank, and a scribe cutter mounted at a distal end of the cutting insert. The cutting insert extends distally through a channel in the pine, and the scribe cutter extends from a distal end surface of the pin in an offset position. The distal end surface of the pin is perpendicular to a longitudinal axis of the shank.
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公开(公告)号：US20210003533A1
公开(公告)日：2021-01-07
申请号：US16914914
申请日：2020-06-29
发明人： Haifeng Zhang
摘要： Aspects of ultrasonic through-wall data communication are described. In some aspects, a sensor device is located in an isolated environment behind a wall. A modulator generates a modulated sensor signal based on the binary sensor signal and a carrier signal. A coaxially aligned pair of electroacoustic transducers that transmits the modulated sensor signal through the wall of the isolated environment. A demodulator demodulates the modulated sensor signal to generate a demodulated binary sensor signal. A sensor data recovery component converts the demodulated binary sensor signal into an image or another sensor parameter.
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39.发明授权公开(公告)号：US10813585B2
公开(公告)日：2020-10-27
申请号：US16715576
申请日：2019-12-16
摘要： An exemplary breath analysis system may include a sampling chamber having a molecule collector disposed therein. The molecule detector may be configured such that volatile organic compounds (VOCs) present in a breath sample introduced to the sampling chamber adhere to the molecule collector. A heating element may introduce heat within the sampling chamber, causing release of at least a portion of the VOCs adhered to the molecule collector. An analysis device (e.g., a mass spectrometer or tetrahertz (THz) spectrometer) may identify one or more target VOCs from among at least the portion of the VOCs released from the molecule collector and generate an output representative of the identified one or more target VOCs. The output may include information that quantitates a concentration of the one or more target VOCs with respect to a source of the breath sample.
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40.发明授权公开(公告)号：US10773244B2
公开(公告)日：2020-09-15
申请号：US16444707
申请日：2019-06-18
发明人： Santanu Das , Sundeep Mukherjee
IPC分类号： B01J21/02 , B01J23/755 , B01J23/83 , B01J35/00 , B01J35/02 , B01J35/08 , B01J37/00 , B01J37/02 , B22F1/00 , B22F1/02 , B22F9/08 , C02F1/72 , C22C1/00 , C22C1/04 , C22C45/08 , C02F101/30 , B01J37/34
摘要： The present invention provides amorphous bi-functional catalytic aluminum metallic glass particles having an aluminum metallic glass core and 2 or more transition metals disposed on the surface of the aluminum metallic glass core to form amorphous bi-functional aluminum metallic glass particles with catalytic activity.
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