专利检索 ap:("University of North Texas Health Science Center at Fort Worth") AND inv:"Leigh A. Johnson" 第 1 页

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发明申请
Personalized Medicine Approach for Treating Cognitive Loss 有权

公开(公告)号：US20210341494A1

公开(公告)日：2021-11-04

申请号：US17361763

申请日：2021-06-29

申请人： University of North Texas Health Science Center at Fort Worth

发明人： Sid E. O'Bryant , Leigh A. Johnson

IPC分类号： G01N33/68 , G16B40/00 , C12Q1/6883 , G16H50/20 , G16B40/20 , G16B40/30

摘要： The present invention includes methods for selecting a therapy for improved cognition as well as prevention of cognitive loss/dysfunction using one or more endophenotypes comprising: obtaining a sample from a subject; measuring biomarkers that differentiate between an inflammatory, a metabolic, a neurotrophic, and a depressive endophenotype; and selecting a course of treatment for the subject based on whether the subject is scored as having a high or a low endophenotype for one or more of the inflammatory, a metabolic, a neurotrophic, and a depressive endophenotypes.