公开(公告)号：US20200148740A1

公开(公告)日：2020-05-14

申请号：US16665101

申请日：2019-10-28

申请人： TOAGOSEI CO., LTD. ,  National University Corporation Nagoya University

发明人： Nahoko Baileykobayashi ,  Tetsuhiko Yoshida ,  Makoto Sawada

IPC分类号： C07K14/705 ,  C07K14/47 ,  A61P35/00

摘要： An antitumor peptide provided according to the present invention includes(1) an S1PR-TM related sequence; and (2) an amino acid sequence functioning as a cell penetrating peptide; wherein the total number of amino acid residues is 100 or less.

公开(公告)号：US20200048499A1

公开(公告)日：2020-02-13

申请号：US16607692

申请日：2018-04-26

申请人： TOAGOSEI CO., LTD.

发明人： Masaru ANDOU ,  Yuushi ANDOU ,  Akitsugu SHIBATA ,  Michihiro KAAI

IPC分类号： C09J4/06 ,  C09J133/20

摘要： An adhesive composition according to the present invention contains a polymerizable monomer (A) and a block copolymer (B) including a polymer block (a) which includes structural units derived from a styrene compound and from a maleimide compound, and an acrylic polymer block (b), in which the polymer block (a) and the acrylic polymer block (b) have a solubility parameter of 10.0 or more and 9.0 or more, respectively; the polymer block (a) contains the structural unit derived from a maleimide compound at a concentration from 30% by mass to 99% by mass with respect to the total mass of the polymer block (a); the polymer block (a) has a glass transition temperature of 150° C. or higher; and the polymer block (b) has a glass transition temperature of 20° C. or lower.

公开(公告)号：US10541423B2

公开(公告)日：2020-01-21

申请号：US15561391

申请日：2016-03-29

申请人： TOAGOSEI CO., LTD.

发明人： Hideo Matsuzaki ,  Naohiko Saito ,  Morikatsu Matsunaga ,  Shinya Kumagai

IPC分类号： H01M4/86 ,  H01M10/0525 ,  C25B1/24 ,  C25B11/04 ,  H01M10/0566

摘要： An electrode mixture layer composition for a nonaqueous electrolyte secondary battery contains an active material, water and a binder. The binder contains a crosslinked polymer of a monomer component including an ethylenically unsaturated carboxylic acid monomer, and a salt thereof. The crosslinked polymer is a polymer that is crosslinked with allyl methacrylate, and an amount of the allyl methacrylate used is 0.1 to 2.0 parts by weight relative to total 100 parts by weight of non-crosslinking monomers, and a content of the crosslinked polymer and salt thereof is 0.5% to 5.0% by weight of the active material.

公开(公告)号：US10421944B2

公开(公告)日：2019-09-24

申请号：US15279890

申请日：2016-09-29

申请人： TOAGOSEI CO. LTD. ,  KEIO UNIVERSITY

发明人： Nahoko Baileykobayashi ,  Kenichi Tanaka ,  Tetsuhiko Yoshida ,  Jun Kudo

IPC分类号： C12N5/0797

摘要： The composition for producing neural stem cells provided by the present invention contains an artificially synthesized synthetic peptide having a neural stem cell-inducing peptide sequence that induces neural stem cells from fibroblasts, and one or two or more pharmaceutically acceptable carriers. The neural stem cell-inducing peptide sequence is any of (i) an amino acid sequence constituting a signal peptide of any protein belonging to the amyloid precursor protein (APP) family, (ii) a partial amino acid sequence of the amino acid sequence of (i), and (iii) a modified amino acid sequence of the amino acid sequence of (i) or (ii).

公开(公告)号：US20190256749A1

公开(公告)日：2019-08-22

申请号：US16343341

申请日：2017-10-16

申请人： TOAGOSEI CO., LTD.

发明人： Takahiro ITOU ,  Makoto IMAHORI

IPC分类号： C09J167/02 ,  C09J11/08

摘要： The polyester-based resin composition according to the present invention is, at least, a polyester-based resin composition including: a polyester resin (A); a surfactant (B); and a terpene-based resin (C), in which the polyester resin (A) is obtained by copolymerizing, as a constituent component, a compound that has, as a frame, a polyalkylene glycol having a number of repeating units of from 3 to 50, in which the surfactant (B) is a non-ionic surfactant having a polyalkylene glycol frame, in which a mixing ratio (A)/(C) of the polyester resin (A) to the terpene-based resin (C) is from 80/20 to 99/1 by mass ratio, and in which the polyester-based resin composition has a water contact angle of 30° or less.

公开(公告)号：US10239287B2

公开(公告)日：2019-03-26

申请号：US14375138

申请日：2013-01-11

申请人： Showa Denko Packaging Co., Ltd. ,  TOAGOSEI CO., LTD.

发明人： Takahiro Ito ,  Junya Komano ,  Makoto Imahori ,  Tetsunobu Kuramoto ,  Yuuji Minamibori

IPC分类号： B32B15/085 ,  B32B7/12 ,  B32B15/20 ,  H01M2/02 ,  B32B27/08 ,  B32B37/12 ,  B32B15/088 ,  B32B27/32 ,  B32B1/02

摘要： A molding packaging material excellent in interlaminar lamination strength is provided, in which it is possible to prevent deterioration of the interlaminar strength due to influences of electrolytes and also possible to prevent deterioration of the interlaminar strength due to influences of heat generation and/or expansion/contraction of the packaging material caused by repetition of charging/discharging. The molding packaging material of the present invention includes a heat resistant resin layer 2 as an outer layer, a polypropylene layer 3 as an inner layer, a metal foil layer 5 arranged between the heat resistant resin layer and the polypropylene layer, wherein at least an inner side surface of the metal foil layer 4 is subjected to a chemical conversion treatment, and the polypropylene layer 3 is laminated on the chemical conversion treatment surface of the metal foil layer via an adhesive layer 5, wherein the adhesive layer 5 is formed by applying an adhesive to the chemical conversion treatment surface of the inner side surface of the metal foil layer 4, the adhesive containing at least an organic solvent, a polyolefin resin having a carboxyl group in which the organic solvent is dissolved and an MFR measured at 130° C. is 5 g/10 min to 42 g/10 min, and a multifunctional isocyanate compound.

公开(公告)号：US10143765B2

公开(公告)日：2018-12-04

申请号：US15522424

申请日：2015-10-05

申请人： TOAGOSEI CO., LTD.

发明人： Kentarou Miyamura ,  Koji Sugiura

IPC分类号： A61L9/014 ,  A61L9/01 ,  A61L9/16 ,  B01J20/16 ,  B01J20/18 ,  B01J20/30 ,  C08K3/34

摘要： Provided are: a deodorizer that has high VOC-adsorbing performance and can exhibit deodorizing properties even in a case in which the deodorizer is kneaded into resin, a deodorizing processed product produced by using the deodorizer, and a method for producing the deodorizer. The deodorizer of the present invention is characterized by including a zeolite represented by the following Formula [1], in which the zeolite is obtained by producing a zeolite and then heating the produced zeolite at a temperature of from 120° C. to 250° C.: xNa2O.Al2O3.ySiO2.zH2O [1]. In Formula [1], x represents a positive number of from 0.5 to 5.0, y represents a positive number of from 80 to 150, and z represents a positive number of from 1 to 20.

公开(公告)号：US10067145B2

公开(公告)日：2018-09-04

申请号：US15033452

申请日：2014-10-30

申请人： TOAGOSEI CO., LTD. ,  KYOTO UNIVERSITY

发明人： Tetsuhiko Yoshida ,  Nahoko Baileykobayashi ,  Yoshinori Yoshida ,  Kazuhisa Chonabayashi

IPC分类号： G01N33/68 ,  C07K7/06 ,  C07K7/08 ,  C07K14/47 ,  C12Q1/6876 ,  G01N15/14 ,  G01N15/00 ,  G01N15/10

摘要： The present invention provides a method that allows highly efficient and highly reliable evaluation of genomic stability of pluripotent stem cells, a method for removing pluripotent stem cells that have been identified as genomically unstable by the evaluation method from a culture of pluripotent stem cells to be evaluated, and a synthetic peptide that can be used for the methods. The methods provided by the present invention include preparing a culture of pluripotent stem cells of interest and analyzing an expression level of calreticulin for the pluripotent stem cells in the culture followed by identifying genomic stability or genomic instability of the stem cells on the basis of the expression level of calreticulin.

公开(公告)号：US20180102542A1

公开(公告)日：2018-04-12

申请号：US15568341

申请日：2016-04-11

申请人： TOAGOSEI CO., LTD.

发明人： Hideo MATSUZAKI ,  Naohiko SAITO ,  Morikatsu MATSUNAGA ,  Shinya KUMAGAI

IPC分类号： H01M4/62 ,  C08F220/06 ,  C08F220/28 ,  H01M4/133 ,  H01M10/0569 ,  H01M10/0525 ,  H01M4/587 ,  H01M10/0568

CPC分类号： H01M4/622 ,  C08F220/06 ,  C08F220/28 ,  C08F2220/281 ,  H01M4/0404 ,  H01M4/133 ,  H01M4/587 ,  H01M4/62 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0566 ,  H01M10/0568 ,  H01M10/0569 ,  H01M2300/0037 ,  Y02E60/122 ,  Y02P70/54 ,  Y02T10/7011

摘要： A binder for nonaqueous electrolyte secondary battery electrodes, which contains an acrylic crosslinked polymer or salt thereof, and which is characterized in that: the acrylic crosslinked polymer contains, in all the constituent monomers thereof, 30-90% by weight of an ethylenically unsaturated carboxylic acid monomer (component (a)) and 10-70% by weight of an ethylenically unsaturated monomer containing no carboxyl group and having an SP value of a homopolymer of 9.0-12.5 (cal/cm3)1/2 (component (b)); and the ratio of monomers having a ratio of an acryloyl group of the total constituent monomers is 70% by weight or more.

公开(公告)号：US20170367416A1

公开(公告)日：2017-12-28

申请号：US15534221

申请日：2015-10-28

申请人： TOAGOSEI CO., LTD.

发明人： Yoshinao YAMADA

IPC分类号： A41D13/11 ,  B01J20/18 ,  A62B18/02 ,  A61L9/16 ,  B01J20/06 ,  A61L9/01 ,  B01J20/22

CPC分类号： A41D13/11 ,  A61L9/01 ,  A61L9/014 ,  A61L9/16 ,  A61L2209/14 ,  A62B18/02 ,  A62B23/025 ,  B01J20/02 ,  B01J20/06 ,  B01J20/10 ,  B01J20/18 ,  B01J20/22

摘要： An object of the invention is to provide a deodorizing filter superior in air-permeability as well as in deodorizing performance with respect to an unpleasant malodorous gas. A further object is to provide such a deodorizing filter and a deodorizing mask that do not have an unpleasant odor in themselves, or even after storage in a hermetically closed environment do not develop unpleasant odor or discoloration, and may be used comfortably. A deodorizing filter for a mask of the invention is provided with 2 or more layers of deodorizing fiber layers including a fiber and a chemisorption-type deodorizer, in which the deodorizing fiber layer contains a polyethylene resin fiber, and the thickness of the deodorizing fiber layer is from 0.15 to 0.4 mm, and the basis weight of the deodorizing fiber layer is from 20 to 45 g/m2.