-
31.外观设计Dual material protective case to retain electronic devices including cell phones and electronic data and communication devices 有权双重材料保护箱，用于保留电子设备，包括手机和电子数据和通信设备-
32.发明授权Bicyclic pyrimidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes 有权二环嘧啶作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病公开(公告)号：US07956061B2
公开(公告)日：2011-06-07
申请号：US11793093
申请日：2006-01-18
申请人： Wallace T. Ashton , Charles G. Caldwell , Hong Dong , Ying-Duo Gao , Giovanna Scapin , Ann E. Weber
发明人： Wallace T. Ashton , Charles G. Caldwell , Hong Dong , Ying-Duo Gao , Giovanna Scapin , Ann E. Weber
IPC分类号： C07D487/04 , A61K31/519 , A61P3/10
CPC分类号： C07D487/04 , C07D495/14
摘要： The present invention is directed to novel substituted bicyclic pyrimidines which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
摘要翻译： 本发明涉及作为二肽基肽酶-IV酶（“DPP-IV抑制剂”）的抑制剂的新型取代的双环嘧啶，其可用于治疗或预防涉及二肽基肽酶-IV酶的疾病， 如糖尿病，特别是2型糖尿病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及二肽基肽酶-IV酶的疾病中的用途。
-
-
34.发明申请Fused phenylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes 有权稠合苯丙氨酸衍生物作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病公开(公告)号：US20060281727A1
公开(公告)日：2006-12-14
申请号：US10573108
申请日：2004-10-29
申请人： Wallace Ashton , Hong Dong , Jinyou Xu
发明人： Wallace Ashton , Hong Dong , Jinyou Xu
IPC分类号： A61K31/513 , A61K31/498 , A61K31/4745 , A61K31/4439 , A61K31/454 , A61K31/397 , C07D487/02 , C07D403/02
CPC分类号： C07D207/10 , A61K38/00 , C07D205/04
摘要： The present invention is directed to fused phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-RV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
摘要翻译： 本发明涉及作为二肽基肽酶-IV酶（“DP-RV抑制剂”）的抑制剂的稠合苯丙氨酸衍生物，其可用于治疗或预防涉及二肽基肽酶-IV酶的疾病，例如 作为糖尿病，特别是2型糖尿病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及二肽基肽酶-IV酶的疾病中的用途。
-
公开(公告)号：US20190352294A1
公开(公告)日：2019-11-21
申请号：US16461849
申请日：2017-11-13
申请人： Ashwin RAO , Brian Alexander MCKITTRICK , Matthew LOMBARDO , Jacqueline D. HICKS , Amy Bittner MCCRACKEN , Hong Dong CHU , Sung-Sau SO , Peter ORTH , Zhicai WU , Ping LAN , John S. DEBENHAM , Brent R. WHITEHEAD , Jerry A. TAYLOR , Zhongxiang SUN , Revathi Reddy KATIPALLY , Jonathan E. GABLE , Markus K. DAHLGREN , Sathesh P. BHAT , Merck Sharp & Dohme Corp.
发明人： Ashwin U. Rao , Brian Alexander McKittrick , Matthew Lombardo , Jacqueline D. Hicks , Amy Bittner McCracken , Hong Dong Chu , Sung-Sau So , Peter Orth , Zhicai Wu , Ping Lan , John S. Debenham , Brent R. Whitehead , Jerry A. Taylor , Zhongxiang Sun , Revathi Reddy Katipally , Jonathan E. Gable , Markus K. Dahlgren , Sathesh P. Bhat
IPC分类号： C07D413/14 , C07D495/04 , A61P7/02
摘要： The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.
-
公开(公告)号：US08377550B2
公开(公告)日：2013-02-19
申请号：US12655366
申请日：2009-12-29
IPC分类号： B32B27/20 , B32B15/092
CPC分类号： H01L23/293 , C08L63/00 , H01L21/563 , H01L24/29 , H01L2224/13099 , H01L2224/16225 , H01L2224/2929 , H01L2224/29386 , H01L2224/32225 , H01L2224/73204 , H01L2224/81911 , H01L2924/14 , Y10T428/23 , Y10T428/25 , Y10T428/259 , Y10T428/31529 , Y10T428/31678 , H01L2924/00014 , H01L2924/00 , H01L2924/05442 , H01L2924/0665
摘要： Methods and associated structures of forming underfill material are described. Those methods may include applying an underfill to an interconnect structure comprising residue from a no clean flux, wherein the underfill comprises at least one of a functionalized nanofiller and a micron-sized filler.
摘要翻译： 描述形成底部填充材料的方法和相关结构。 这些方法可以包括将底部填充物施加到包含来自不干净焊剂的残余物的互连结构，其中底部填充物包括官能化纳米填料和微米级填料中的至少一种。
-
-
-
39.发明申请TRICYCLIC HETEROAROMATIC COMPOUNDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES 有权作为治疗或预防糖尿病的DIPEPTIDYL PEPTIDASE-IV抑制剂的三环异构体化合物公开(公告)号：US20100056550A1
公开(公告)日：2010-03-04
申请号：US12513190
申请日：2007-11-09
申请人： Jason M. Cox , Hong Dong
发明人： Jason M. Cox , Hong Dong
IPC分类号： A61K31/519 , C07D487/14 , A61P3/10
CPC分类号： C07D487/14
摘要： The present invention is directed to novel substituted tricyclic heteroaromatic compounds of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
摘要翻译： 本发明涉及结构式（I）的新型取代三环杂芳族化合物，其为二肽基肽酶-IV酶的抑制剂，其可用于治疗或预防涉及二肽基肽酶-IV酶的疾病，例如 作为糖尿病，特别是2型糖尿病。 本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及二肽基肽酶-IV酶的疾病中的用途。
-
-
-
-
-
-
-
-
-
搜索结果
41 条记录 (耗时 0.018 秒)
