System and method for high gain Raman spectroscopy

    公开(公告)号:US11860106B1

    公开(公告)日:2024-01-02

    申请号:US18302954

    申请日:2023-04-19

    Abstract: A system for high gain stimulated Raman spectroscopy comprises a first continuous wave laser having an output beam at a tunable optical frequency modulated at a first RF frequency, a second continuous wave laser having a second output beam at an optical frequency modulated at a second RF frequency, wherein the modulation frequencies are selected such that their beat notes represent a Raman resonance frequency, a dual-beam rasterizing probe including first and second photosensors and a rasterizer configured to scan the first and second laser output beams onto a sample, exposing the sample to a reduced average power of laser radiation stimulating the sample to emit Raman radiation signals. The Raman signals are directed to the photosensors and the outputs of the photosensors are supplied to a differential amplifier configured to provide sensitivity and gain to signals at the beat note resonant frequency and to filter signals at other frequencies.

    Low-cost, compact chromatic confocal module

    公开(公告)号:US11473975B2

    公开(公告)日:2022-10-18

    申请号:US17054735

    申请日:2019-05-09

    Inventor: Rongguang Liang

    Abstract: Devices, systems and methods for use in confocal imaging systems are described that enable lateral and axial scans at high speeds and without a moving scanner while producing high quality images. One chromatic confocal optical head includes an illumination source, such as an addressable point source array, to provide a wide spectrum illumination including multiple wavelengths. The optical head also includes a beamsplitter to allow the light to be directed toward an object, to receive the reflected light from the object and to direct the reflected light toward a detector. The optical head further includes a pinhole mask that is positioned to receive the light that is reflected from the object after passing through the beamsplitter, and a dispersion element that is positioned to receive the light after passing through the pinhole mask, and to separate the light into multiple spectral components for reception by the detector.

    Light pipe for spectroscopy
    314.
    发明授权

    公开(公告)号:US11442004B2

    公开(公告)日:2022-09-13

    申请号:US16946309

    申请日:2020-06-16

    Abstract: A spectroscopic assembly may include a spectrometer. The spectrometer may include an illumination source to generate a light to illuminate a sample. The spectrometer may include a sensor to obtain a spectroscopic measurement based on light, reflected by the sample, from the light illuminating the sample. The spectroscopic assembly may include a light pipe to transfer the light reflected from the sample. The light pipe may include a first opening to receive the spectrometer. The light pipe may include a second opening to receive the sample, such that the sample is enclosed by the light pipe and a base surface when the sample is received at the second opening. The light pipe may be associated with aligning the illumination source and the sensor with the sample.

    Optical endoluminal far-field microscopic imaging catheter

    公开(公告)号:US11330969B2

    公开(公告)日:2022-05-17

    申请号:US15786550

    申请日:2017-10-17

    Abstract: An optical endoluminal far-field microscopic imaging catheter comprises a light generating system, a first light delivery conduit for propagating light generated by the light generating system and a light distributor configured to redirect light propagated by the delivery conduit into a direction of an object to be imaged. A discriminator is configured for capturing light reflected from the object incident on a window of the discriminator from a particular direction and transmitting only the light captured from the particular direction to a second light delivery conduit. A drive mechanism is configured to sweep the window through a plurality of directions in a predictable pattern for matching each light capture event in the window with a direction of the window during the event. An analyzer matches the direction of the window with an associated light capture event and generate a visible image based on a mosaic of the captured light.

    Method of calibrating spectral apparatus and method of producing calibrated spectral apparatus

    公开(公告)号:US11307093B2

    公开(公告)日:2022-04-19

    申请号:US16986884

    申请日:2020-08-06

    Abstract: Creating a model calibrating spectral apparatus having an optical system that converts light to be measured into a spectrum, and a light-receiving sensor including a plurality of sensors that outputs signals, the sensors include sensors that output signals indicating respective energy amounts of a plurality of wavelength components. The model shows where a linear function of an indicator indicating a mechanical error in the spectral apparatus, expresses deviation of an indicator indicating spectral sensitivity of the sensor from the indicator indicating the reference spectral sensitivity of the sensor. The method comprises: a) acquiring reference spectral sensitivity; b) acquiring an indicator indicating the reference spectral sensitivity of the sensor acquired at a); and c) creating the model where the linear function of the mechanical error indicator expresses deviation of the spectral sensitivity indicator from the indicator indicating the reference spectral sensitivity of the sensor, acquired at b).

    Housing system for Michelson interferometer

    公开(公告)号:US11162775B2

    公开(公告)日:2021-11-02

    申请号:US15657385

    申请日:2017-07-24

    Abstract: The present invention relates to a housing of a Michelson interferometer that may facilitate optical alignment of a plurality of optical components by applying a two-part structured housing to the Michelson interferometer. The present invention may provide a Michelson interferometer housing system including a first housing including a first surface on which a fixed mirror is installed, a second surface perpendicular to the first surface, and a first diagonal surface on which a beam splitter assembly to which light is incident from the outside is installed, the first diagonal surface being formed at 45 degrees with respect to the second surface; and a second housing including a third surface on which a movable mirror is installed, a fourth surface perpendicular to the third surface, and a second diagonal surface corresponding to the first diagonal surface, wherein the first and second housings are combined such that the first and second diagonal surfaces face each other to allow the light entering from the outside to be divided through the beam splitter assembly and incident to the fixed mirror and the movable mirror.

    SPECTRAL FEATURE CONTROL APPARATUS
    318.
    发明申请

    公开(公告)号:US20210011302A1

    公开(公告)日:2021-01-14

    申请号:US17034132

    申请日:2020-09-28

    Applicant: Cymer, LLC

    Abstract: A spectral feature selection apparatus includes a dispersive optical element arranged to interact with a pulsed light beam; three or more refractive optical elements arranged in a path of the pulsed light beam between the dispersive optical element and a pulsed optical source; and one or more actuation systems, each actuation system associated with a refractive optical element and configured to rotate the associated refractive optical element to thereby adjust a spectral feature of the pulsed light beam. At least one of the actuation systems is a rapid actuation system that includes a rapid actuator configured to rotate its associated refractive optical element about a rotation axis. The rapid actuator includes a rotary stepper motor having a rotation shaft that rotates about a shaft axis that is parallel with the rotation axis of the associated refractive optical element.

    LIGHT PIPE FOR SPECTROSCOPY
    319.
    发明申请

    公开(公告)号:US20200309680A1

    公开(公告)日:2020-10-01

    申请号:US16946309

    申请日:2020-06-16

    Abstract: A spectroscopic assembly may include a spectrometer. The spectrometer may include an illumination source to generate a light to illuminate a sample. The spectrometer may include a sensor to obtain a spectroscopic measurement based on light, reflected by the sample, from the light illuminating the sample. The spectroscopic assembly may include a light pipe to transfer the light reflected from the sample. The light pipe may include a first opening to receive the spectrometer. The light pipe may include a second opening to receive the sample, such that the sample is enclosed by the light pipe and a base surface when the sample is received at the second opening. The light pipe may be associated with aligning the illumination source and the sensor with the sample.

Patent Agency Ranking