Abstract:
The present invention includes a comprehensive replacement fluid system and method for the delivery of regional citrate anticoagulation (RCA) to extracorporeal blood circuits, wherein the system may include an online clearance monitor (OCM) and a circuit effluent online sensor system (OSS) for the continuous determination of patient plasma content of ultrafilterable soultes.
Abstract:
The invention provides a method and apparatus for continuous monitoring of permeate from membrane elements in a water treatment plant, including a desalination plant. The apparatus includes a probe that includes multiple sensors such that at least one sensor is associated with each membrane element. Each sensor is coupled to a node, which is configured to communicate a signal associated with the permeate quality to a central node sink. The node may communicate wirelessly with the node sink.
Abstract:
The present invention generally relates to a water treatment system and a sanitization system and method. A sanitization fluid, typically water at a pharmaceutically acceptable temperature, is intermittently provided to the water treatment system for minimal periods of time.
Abstract:
A water treatment system is provided having an encapsulate manifold with a reverse osmosis cartridge and one or more filter cartridges, and an annular collar to adapt and connect the manifold to the cartridges. The filter cartridge includes a detent for being received within a slot in the manifold head for secure locking engagement. The water treatment system is also provided in a modular arrangement wherein manifold heads are physically and fluidly coupled together via a clip which interfaces with the modular manifold heads. The water treatment system also allows for a retrofit application to include a permeate pump. The cartridges are also designed to provide a minimum annular inlet gap to minimize spillage during changing of the cartridges.
Abstract:
A method for conductivity calculation in a treatment fluid downstream a filtration unit in a blood treatment apparatus is provided. The conductivity calculation is then used for clearance and fistula flow determination. A flow of treatment fluid is created in the filtration unit; a change in the conductivity of the treatment fluid at the inlet of the filtration unit is imposed to cause an induced conductivity change in the fluid at the outlet of the filtration unit; a predetermined number of conductivity values Cdo downstream from the filtration unit are measured. The measured conductivity values define a curve the pattern of which is estimated by means of one interpolating mathematical function in an interval of time after the occurrence of the induced conductivity change; a characteristic measuring time tcalcclr is determined. The value of the interpolating mathematical function at the characteristic measuring time tcalcclr represents the conductivity value Cdo2 of the treatment fluid downstream from the filtration unit after the induced conductivity change.
Abstract:
A water treatment system is provided having an encapsulate manifold with a reverse osmosis cartridge and one or more filter cartridges. The filter cartridge includes a detent for being received within a slot in the manifold head for secure locking engagement. The water treatment system further includes a single probe conductivity monitoring system for monitoring the performance of a reverse osmosis membrane. The water treatment system is also provided in a modular arrangement wherein manifold heads are physically and fluidly coupled together via a clip which interfaces with the modular manifold heads. The water treatment system also allows for a retrofit application to include a permeate pump. The cartridges are also designed to provide a minimum annular inlet gap to minimize spillage during changing of the cartridges.
Abstract:
New methods and apparatus are described for assessing the integrity of a separation module or filtration system. A principle embodiment concerns use of a transient pulse of challenge species to probe a spiral wound module. The resulting time-dependent concentration of challenge species in the permeate is detected, recorded, and compared to a reference. An apparatus is further claimed for detecting permeate conductivity at multiple points within the permeate collection tube of a spiral wound module. Also disclosed is a process whereby the permeate stream from a filtration system is concentration by a high recovery membrane apparatus prior to measurement of challenge species concentration.
Abstract:
The present invention includes a comprehensive replacement fluid system and method for the delivery of regional citrate anticoagulation (RCA) to extracorporeal blood circuits, wherein the system may include an online clearance monitor (OCM) and a circuit effluent online sensor system (OSS) for the continuous determination of patient plasma content of ultrafilterable soultes.
Abstract:
A closed loop water purification system comprising a feed water line (42) to supply feed water, a high pressure feed pump (62), a filter assembly (66) having an inlet supplied by the high pressure feed pump, a distribution line (68) and a reject water line (70), the reject line returning reject water from the filter assembly to the feed water line, the distribution line supplying at least one purified water take off point (86) and returning to a junction (50) in the feed water line upstream of the high pressure feed pump. The reject water line is connected to the junction in the feed water line upstream of the high pressure feed pump. A first backflow prevention device (48) is on the feed water line upstream of the junction. A second backflow prevention device (100) is on the distribution line upstream of the junction and a third backflow prevention device (80) is on the reject water line upstream of the junction. A heater system (56) is in one of the distribution line, the reject line or the feed water line.
Abstract:
An apparatus for continuous closed-circuit consecutive sequential desalination of a salt water solution by reverse osmosis that comprises a closed circuit system comprising one or more desalination modules having their respective inlets and outlets connected in parallel by conducing lines, each of desalination modules comprising of one or more membrane elements, a pressurizing device for creating counter pressure to enable reverse osmosis desalination and replacement of released permeate by fresh, a circulation system for recycling the desalinated solution through the desalination modules, a conducting line systems for permeate collection from the desalination modules, a conducting line system for removing brine effluent a valve system to enable periodic discharge of brine from the closed circuit without stopping desalination, and monitoring and control systems to enable continuous closed circuit desalination of desired recovery proceed in consecutive sequential steps under variable or constant pressure conditions.