公开(公告)号：US08468986B2

公开(公告)日：2013-06-25

申请号：US12785754

申请日：2010-05-24

申请人： Tomoki Ito ,  Satoshi Watanabe

发明人： Tomoki Ito ,  Satoshi Watanabe

IPC分类号： F01L1/34 ,  F02M51/00 ,  F02B47/08

CPC分类号： F02D41/064 ,  F02D13/023 ,  F02D13/0238 ,  F02D13/0261 ,  F02D41/345 ,  F02D2013/0292 ,  F02D2041/001 ,  Y02T10/18 ,  Y02T10/44

摘要： An engine fuel injection control apparatus includes a variable valve device that at least varies an intake valve open timing of an intake valve. A controller adjusts the variable valve device and a fuel injection timing of a fuel injection valve. The controller controls a fuel injection end timing in accordance with an overlap amount of the intake valve and an exhaust valve. The controller adjusts the fuel injection timing such that the fuel injection end timing is more advanced than the intake valve open timing and such that as an amount by which the overlap amount exceeds a prescribed overlap amount becomes larger, a time interval between the fuel injection end timing and the intake valve open timing is set to become increasingly larger, upon determining that the engine is being cold started and the overlap amount is larger than the prescribed overlap amount.

摘要翻译： 发动机燃料喷射控制装置包括至少改变进气门的进气门打开正时的可变气门装置。 控制器调节可变阀装置和燃料喷射阀的燃料喷射正时。 控制器根据进气门和排气阀的重叠量控制燃油喷射结束时刻。 控制器调节燃料喷射正时，使得燃料喷射结束正时比进气门打开正时更前进，并且使得当重叠量超过规定重叠量的量变大时，燃料喷射端之间的时间间隔 在确定发动机冷起动并且重叠量大于规定重叠量时，定时和进气门打开正时被设定为越来越大。

公开(公告)号：US08464766B2

公开(公告)日：2013-06-18

申请号：US12622236

申请日：2009-11-19

申请人： Tomoki Ito ,  Takayuki Sato ,  Tomomi Nakaya

发明人： Tomoki Ito ,  Takayuki Sato ,  Tomomi Nakaya

IPC分类号： B65B1/04 ,  B65B3/00 ,  B67C3/00

CPC分类号： B60K15/07 ,  B60K15/03006 ,  F02M21/0221 ,  F02M21/029 ,  F02M21/0296 ,  F17C13/084 ,  Y02T10/32 ,  Y10T137/7039

摘要： Cylinder mounting mechanism is provided in a working machine for mounting thereto a cylinder case having a cassette gas cylinder accommodated therein. Mouthpiece support section is provided in the mounting mechanism for supporting a mouthpiece portion of the cassette gas cylinder in the cylinder case. Fitting recessed portion is provided in one end portion of the cylinder case and capable of receiving the mouthpiece support section, the fitting recessed portion being defined by an inner peripheral wall part of the one end portion that has a tapering wall thickness such that the surface of the wall part slants gradually outwardly toward the distal end of the fitting recessed portion.

摘要翻译： 气缸安装机构设置在工作机中，用于安装在其上容纳有盒式气瓶的气缸壳体。 在安装机构中设置有口部支撑部，用于将气瓶内的盒式气瓶的接口部分支撑。 配合凹部设置在气缸壳体的一个端部并且能够容纳接口支撑部分，该配合凹部由一个端部的内周壁部分限定，该内壁部分具有锥形壁厚度， 壁部朝向嵌合凹部的前端逐渐向外倾斜。

公开(公告)号：US08307803B2

公开(公告)日：2012-11-13

申请号：US12471001

申请日：2009-05-22

申请人： Tomoki Ito ,  Hideaki Kobayashi ,  Tomomi Nakaya ,  Masayuki Sasaoka

发明人： Tomoki Ito ,  Hideaki Kobayashi ,  Tomomi Nakaya ,  Masayuki Sasaoka

IPC分类号： F02B67/00

CPC分类号： F17C13/084 ,  B60K15/07 ,  B60Y2200/41 ,  F17C13/085 ,  F17C2201/0104 ,  F17C2201/058 ,  F17C2205/0107 ,  F17C2205/0119 ,  F17C2205/0126 ,  F17C2205/0157 ,  F17C2260/025 ,  F17C2270/0184

摘要： A work machine to which a cassette gas cylinder is detachably attached is disclosed. The cassette gas cylinder is accommodated inside a gas cylinder case. The gas cylinder case for accommodating the cassette gas cylinder is detachably attached to the work machine so that the gas cylinder case wherein the cassette gas cylinder is accommodated can be transported together with the cylinder.

摘要翻译： 公开了一种可拆卸地安装盒式气瓶的工作机。 盒式气瓶容纳在气瓶壳体内。 用于容纳盒式气瓶的气瓶壳体可拆卸地附接到作业机器，使得容纳盒式气瓶的气瓶壳体可与气缸一起输送。

公开(公告)号：US20120269825A1

公开(公告)日：2012-10-25

申请号：US13456589

申请日：2012-04-26

申请人： Yong-Jun Liu ,  Tomoki Ito

发明人： Yong-Jun Liu ,  Tomoki Ito

IPC分类号： A61K39/395 ,  G01N33/53 ,  A61P35/00

CPC分类号： G01N33/5011 ,  A61K2039/505 ,  C07K16/2878 ,  C07K2317/73 ,  C07K2317/75 ,  G01N2333/5434 ,  G01N2333/70578

摘要： Numerous disease states, such as human allergic, autoimmune, and autoimmune diseases, and cancer, may be treated by targeting OX40/OX40L. OX40L inhibits the generation of Tr1 cells from naïve and memory CD4+ T cells. This unique function of OX40L is not shared by two other costimulatory TNF-family members, GITR-ligand and 4-1BB-ligand. It has been shown that signaling the OX40-receptor on human T cells by antibodies, small molecules, or the OX40L modulates the generation and function of IL-10 producing Foxp3+ Treg immunosuppressive T cells and blocks Foxp3+ Treg function. Further, provided are high throughput methods for identifying compounds that can inhibit the immunosuppressive function of IL-10 producing Tr1 cells.

摘要翻译： 可以通过靶向OX40 / OX40L来治疗许多疾病状态，例如人类过敏，自身免疫和自身免疫性疾病和癌症。 OX40L抑制从初始和记忆的CD4 + T细胞产生Tr1细胞。 OX40L的这种独特功能不是由另外两种共刺激的TNF-家族成员，GITR-配体和4-1BB-配体共享。 已经表明，通过抗体，小分子或OX40L来传递人T细胞上的OX40受体，调节IL-10产生的Foxp3 + Treg免疫抑制性T细胞的产生和功能并阻断Foxp3 + Treg功能。 此外，提供了用于鉴定可以抑制产生IL-10的Tr1细胞的免疫抑制功能的化合物的高通量方法。

公开(公告)号：US08191659B2

公开(公告)日：2012-06-05

申请号：US12991306

申请日：2009-04-03

申请人： Hideaki Kobayashi ,  Tomoki Ito

发明人： Hideaki Kobayashi ,  Tomoki Ito

IPC分类号： B60K15/063 ,  B62D51/04

CPC分类号： B60K15/07 ,  A01B33/028 ,  A01B33/16 ,  B60Y2200/41 ,  F17C13/085 ,  F17C2205/0111 ,  F17C2205/0165 ,  F17C2221/035 ,  F17C2223/0153 ,  F17C2223/033 ,  F17C2270/0736

摘要： A walking-type working machine in which a gas-container housing section (cassette-type gas container) and a carry handle are mounted to a handle post. The walking-type working machine (10) is provided with a cassette-type gas container (21) mounted to a handle post (16), which rises upward and rearward from a rear section (11a) of a working machine body (11), so as to be oriented in the longitudinal direction of the handle post. A gas engine (12) is driven by fuel in the cassette-type gas container (21). The walking-type working machine is provided with a carry handle (22) for carrying the machine. The carry handle (22) is mounted to the handle post and is formed so as to surround the cassette-type gas container. The carry handle has a grip (45).

摘要翻译： 一种行走型工作机，其中气体容器容纳部分（盒式气体容器）和携带手柄安装在手柄柱上。 步行式加工机10具有安装在从工作机体11的后部11a上下升起的手柄柱16的盒式气体容器21， 以便在手柄柱的纵向方向上定向。 气体发动机（12）由盒式气体容器（21）中的燃料驱动。 步行式工作机器设置有用于承载机器的便携手柄（22）。 携带把手（22）安装在手柄柱上并形成为围绕盒式气体容器。 手柄具有握把（45）。

公开(公告)号：US07961409B2

公开(公告)日：2011-06-14

申请号：US12139464

申请日：2008-06-14

申请人： Hiroshi Yamamoto ,  Tomoki Ito ,  Takeshi Suzuki

发明人： Hiroshi Yamamoto ,  Tomoki Ito ,  Takeshi Suzuki

IPC分类号： G02B9/12

CPC分类号： G02B15/177 ,  G02B27/646

摘要： Providing a zoom lens system having excellent optical performance, an optical apparatus, and a method for zooming the zoom lens system. The zoom lens system includes, in order from an object, a first lens group G1 having negative refractive power, a second lens group G2 having positive refractive power, and a third lens group G3 having negative refractive power. Upon zooming from a wide-angle end state W to a telephoto end state T, each distance between adjacent lens groups is varied. The second lens group G2 includes, in order from the object, a front group G2a having positive refractive power, and a rear group G2b. Focusing on the object is carried out by moving the front group G2a along an optical axis. Given conditional expressions are satisfied.

摘要翻译： 提供具有优异的光学性能的变焦透镜系统，光学装置和用于变焦变焦透镜系统的变焦方法。 变焦透镜系统从物体起依次包括具有负折光力的第一透镜组G1，具有正折光力的第二透镜组G2和具有负折光力的第三透镜组G3。 在从广角端状态W变焦到望远端状态T时，相邻透镜组之间的每个距离变化。 第二透镜组G2从物体起依次包括具有正屈光力的前组G2a和后组G2b。 通过沿着光轴移动前组G2a来实现对象的聚焦。 给定条件表达式是满意的。

公开(公告)号：US20100126788A1

公开(公告)日：2010-05-27

申请号：US12625160

申请日：2009-11-24

申请人： Tomoki Ito ,  Koichi Azuma ,  Tomomi Nakaya ,  Masayuki Sasaoka

发明人： Tomoki Ito ,  Koichi Azuma ,  Tomomi Nakaya ,  Masayuki Sasaoka

IPC分类号： B60K15/00

CPC分类号： B60K15/07 ,  B60K15/03006 ,  F02M21/0221 ,  F02M21/0242 ,  F02M21/029 ,  F17C13/084 ,  F17C2201/0119 ,  F17C2203/0614 ,  F17C2205/0111 ,  F17C2205/0126 ,  F17C2205/0305 ,  F17C2205/0323 ,  F17C2223/0123 ,  F17C2265/012 ,  F17C2265/066 ,  F17C2270/0745 ,  Y02T10/32

摘要： A work vehicle includes an engine driven by gas fuel sealed inside a cassette gas cylinder. The cassette gas cylinder is installed in a cylinder mount. The cylinder mount comprises a mouthpiece support for supporting a mouthpiece of the cassette gas cylinder, and a shutter member swingable about a support shaft provided to the cylinder mount, for opening and closing an opening of the mouthpiece support from above the mouthpiece support.

摘要翻译： 工作车辆包括由气体燃料驱动的发动机，其被密封在盒式气瓶内。 盒式气瓶安装在气缸安装座中。 气缸安装座包括用于支撑盒式气瓶的吸口的接口支撑件，以及围绕设置在气缸座上的支撑轴可摆动的活门构件，用于从吹口支架上方打开和关闭接口支撑件的开口。

公开(公告)号：US20100126595A1

公开(公告)日：2010-05-27

申请号：US12622236

申请日：2009-11-19

申请人： Tomoki Ito ,  Takayuki Sato ,  Tomomi Nakaya

发明人： Tomoki Ito ,  Takayuki Sato ,  Tomomi Nakaya

IPC分类号： B65D25/00

CPC分类号： B60K15/07 ,  B60K15/03006 ,  F02M21/0221 ,  F02M21/029 ,  F02M21/0296 ,  F17C13/084 ,  Y02T10/32 ,  Y10T137/7039

摘要： Cylinder mounting mechanism is provided in a working machine for mounting thereto a cylinder case having a cassette gas cylinder accommodated therein. Mouthpiece support section is provided in the mounting mechanism for supporting a mouthpiece portion of the cassette gas cylinder in the cylinder case. Fitting recessed portion is provided in one end portion of the cylinder case and capable of receiving the mouthpiece support section, the fitting recessed portion being defined by an inner peripheral wall part of the one end portion that has a tapering wall thickness such that the surface of the wall part slants gradually outwardly toward the distal end of the fitting recessed portion.

摘要翻译： 气缸安装机构设置在工作机中，用于安装在其上容纳有盒式气瓶的气缸壳体。 在安装机构中设置有口部支撑部，用于将气瓶内的盒式气瓶的接口部分支撑。 配合凹部设置在气缸壳体的一个端部并且能够容纳接口支撑部分，该配合凹部由一个端部的内周壁部分限定，该内壁部分具有锥形壁厚度， 壁部朝向嵌合凹部的前端逐渐向外倾斜。

公开(公告)号：US20090161227A1

公开(公告)日：2009-06-25

申请号：US12342315

申请日：2008-12-23

申请人： Hiroshi Yamamoto ,  Tomoki Ito ,  Satoshi Yamaguchi ,  Atsushi Shibayama

发明人： Hiroshi Yamamoto ,  Tomoki Ito ,  Satoshi Yamaguchi ,  Atsushi Shibayama

IPC分类号： G02B15/14

CPC分类号： G02B15/173 ,  G02B27/646

摘要： A zoom optical system has a first lens group having a positive refracting power; a second lens group having a negative refracting power; a third lens group having a positive refracting power; a fourth lens group having a negative refracting power; and a fifth lens group having a positive refracting power, in the order from the object side. The fourth lens group is composed of a cemented lens of a negative lens and a positive lens in the order from the object side, and a condition of the following expression is satisfied: vp>30.0, where vp is an Abbe number of the positive lens.

摘要翻译： 变焦光学系统具有正折射率的第一透镜组; 具有负折射率的第二透镜组; 具有正折射率的第三透镜组; 具有负折射力的第四透镜组; 以及从物体侧开始的顺序具有正折射率的第五透镜组。 第四透镜组由物镜侧的顺序由负透镜和正透镜的胶合透镜构成，满足以下条件：vp> 30.0，其中vp是正透镜的阿贝数 。

公开(公告)号：US20090002841A1

公开(公告)日：2009-01-01

申请号：US12139464

申请日：2008-06-14

申请人： Hiroshi Yamamoto ,  Tomoki Ito ,  Takeshi Suzuki

发明人： Hiroshi Yamamoto ,  Tomoki Ito ,  Takeshi Suzuki

IPC分类号： G02B15/177

CPC分类号： G02B15/177 ,  G02B27/646

摘要： Providing a zoom lens system having excellent optical performance, an optical apparatus, and a method for zooming the zoom lens system. The zoom lens system includes, in order from an object, a first lens group G1 having negative refractive power, a second lens group G2 having positive refractive power, and a third lens group G3 having negative refractive power. Upon zooming from a wide-angle end state W to a telephoto end state T, each distance between adjacent lens groups is varied. The second lens group G2 includes, in order from the object, a front group G2a having positive refractive power, and a rear group G2b. Focusing on the object is carried out by moving the front group G2a along an optical axis. Given conditional expressions are satisfied.

摘要翻译： 提供具有优异的光学性能的变焦透镜系统，光学装置和用于变焦变焦透镜系统的变焦方法。 变焦透镜系统从物体起依次包括具有负折光力的第一透镜组G1，具有正折光力的第二透镜组G2和具有负折光力的第三透镜组G3。 在从广角端状态W变焦到望远端状态T时，相邻透镜组之间的每个距离变化。 第二透镜组G2从物体起依次包括具有正屈光力的前组G2a和后组G2b。 通过沿着光轴移动前组G2a来实现对象的聚焦。 给定条件表达式是满意的。