公开(公告)号：US20160350915A1

公开(公告)日：2016-12-01

申请号：US15166195

申请日：2016-05-26

Applicant: OLYMPUS CORPORATION

Inventor： Kosuke TAKAGI ,  Yoshihiro SHIMADA

IPC: G06T7/00 ,  G06T7/60 ,  G06K9/52 ,  G01N33/483 ,  G06K9/62

CPC classification number: G06T7/0012 ,  G01N33/4833 ,  G06K9/0014 ,  G06K9/52 ,  G06T7/66 ,  G06T7/70 ,  G06T2200/04 ,  G06T2207/30004 ,  G06T2207/30024

Abstract: A cell evaluation method includes: a labeling step of labeling at least some of cells constituting a cell clump with a chemical substance; an image-capturing step of acquiring a plurality of slice images of the labeled cells, for at least part of the cell clump; an evaluating step of evaluating the characteristics of the cells on the basis of the plurality of slice images; a 3D-image creating step of creating a 3D image of at least part of the cell clump by subjecting the plurality of slice images to image processing; a center-of-gravity determining step of determining, from the 3D image, a center-of-gravity position of the cell clump; and an organizing step of organizing evaluation results obtained in the evaluating step, with respect to the distance from the center-of-gravity position.

Abstract translation: 细胞评价方法包括：标记步骤，用化学物质标记构成细胞团的至少一些细胞; 对于所述细胞团的至少一部分，获取所述标记细胞的多个切片图像的图像捕获步骤; 评估步骤，基于所述多个切片图像来评估所述单元的特性; 3D图像创建步骤，通过对所述多个切片图像进行图像处理来创建所述细胞团的至少一部分的3D图像; 重心确定步骤，从3D图像确定细胞团的重心位置; 以及组织步骤，用于组织在评估步骤中获得的评估结果相对于距离重心位置的距离。