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公开(公告)号:US20160102146A1
公开(公告)日:2016-04-14
申请号:US14856731
申请日:2015-09-17
Applicant: GENENTECH, INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/28
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20160075787A1
公开(公告)日:2016-03-17
申请号:US14852369
申请日:2015-09-11
Applicant: GENENTECH, INC.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang
IPC: C07K16/28 , A61K31/706 , G01N33/574 , A61K31/5517 , A61K51/10 , C07K16/30 , A61K47/48
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CLL-1抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20140030280A1
公开(公告)日:2014-01-30
申请号:US13936280
申请日:2013-07-08
Applicant: Genentech, Inc.
Inventor: Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu
IPC: A61K47/48 , A61K45/06 , A61K31/551
CPC classification number: A61K47/6813 , A61K31/551 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867 , A61K2300/00
Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20130089555A1
公开(公告)日:2013-04-11
申请号:US13682581
申请日:2012-11-20
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/28 , A61K38/19 , A61K31/56 , A61K39/00 , A61K31/69 , A61K33/24 , A61K31/138 , A61K31/4196 , A61K31/5685 , A61K31/4745 , A61K31/568 , A61K31/517 , A61K39/395 , A61K31/454
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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25.ANTI-FcRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE 审中-公开
Title translation: ANTI-FcRH5抗体和免疫球蛋白及其使用方法公开(公告)号:US20130089497A1
公开(公告)日:2013-04-11
申请号:US13673565
申请日:2012-11-09
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/395 , A61K31/69
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US11084877B2
公开(公告)日:2021-08-10
申请号:US16250398
申请日:2019-01-17
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: A61K39/00 , C07K16/28 , A61K47/68 , A61K31/5517 , A61K31/706 , A61K51/10 , C07K16/30 , G01N33/574
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:USRE48558E1
公开(公告)日:2021-05-18
申请号:US15908703
申请日:2018-02-28
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K51/00 , A61K39/44 , C07K19/00 , C07K16/28 , A61K47/68 , A61K31/537 , A61K38/05 , A61K39/395 , A61K45/06 , A61K51/10 , C07K16/30 , G01N33/574 , A61K39/00
Abstract: The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.
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公开(公告)号:US10981987B2
公开(公告)日:2021-04-20
申请号:US15803495
申请日:2017-11-03
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K51/00 , A61K39/395 , A61K39/40 , C07K16/28 , C07K16/30 , A61K51/10 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US10239947B2
公开(公告)日:2019-03-26
申请号:US15657471
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K31/5517 , A61K31/706 , A61K51/10 , C07K16/30 , G01N33/574 , A61K47/68
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10227412B2
公开(公告)日:2019-03-12
申请号:US15657476
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: G01N33/574 , C07K16/28 , A61K31/5517 , A61K31/706 , A61K51/10 , C07K16/30 , A61K47/68
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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