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    DRUG DELIVERY DEVICE WITH INTERLOCK ASSEMBLY AND RELATED METHOD OF ASSEMBLY
    22.
    发明申请
    DRUG DELIVERY DEVICE WITH INTERLOCK ASSEMBLY AND RELATED METHOD OF ASSEMBLY 审中-公开

    公开(公告)号：US20200254172A1

    公开(公告)日：2020-08-13

    申请号：US16753711

    申请日：2018-10-01

    Applicant: AMGEN INC.

    Inventor： Ronald Forster ,  Gregory Gordon ,  Martin Hering ,  Matthew Wayne Janke ,  Andrew N. King ,  Wael Mismar

    IPC: A61M5/145 ,  A61M5/315 ,  A61M5/142

    Abstract: Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a housing, a container, a trigger member, and an interlock assembly. The trigger member may be selectively moveable relative to the housing to activate operation of at least one activatable element of the drug delivery device. The interlock assembly may include a lever mounted rotatably relative to the housing, a proximity sensor moveable between a first position extending beyond an exterior surface of the housing and a second position retracted toward the housing, and a rotational biasing member operably connected to the proximity sensor via the lever. When the proximity sensor is in the first position, the interlock assembly may limit movement of the trigger member relative to the housing. The rotational biasing member may be configured to exert a torque biasing the proximity sensor toward the first sensor position.

    METHOD OF ASSEMBLING AND FILLING A DRUG DELIVERY DEVICE
    25.
    发明申请
    METHOD OF ASSEMBLING AND FILLING A DRUG DELIVERY DEVICE 审中-公开
    装配和填充药物递送装置的方法

    公开(公告)号：US20160199583A1

    公开(公告)日：2016-07-14

    申请号：US15047815

    申请日：2016-02-19

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Son C. Tran ,  Sheldon Moberg ,  Mark D. Holt

    IPC: A61M5/31 ,  B65B55/10 ,  B65B55/08 ,  B65B3/00 ,  B65B7/28

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有带有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了填充有药物产品的封闭的无菌容器，其包括粒细胞集落刺激因子 （G-CSF）。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

    INJECTOR AND METHOD OF ASSEMBLY
    26.
    发明申请
    INJECTOR AND METHOD OF ASSEMBLY 审中-公开
    注射器和组装方法

    公开(公告)号：US20160199578A1

    公开(公告)日：2016-07-14

    申请号：US15040308

    申请日：2016-02-10

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

    IPC: A61M5/24 ,  A61M5/172

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了充满药物的封闭的无菌容器。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

    INJECTOR AND METHOD OF ASSEMBLY
    27.
    发明申请
    INJECTOR AND METHOD OF ASSEMBLY 审中-公开
    注射器和组装方法

    公开(公告)号：US20160166765A1

    公开(公告)日：2016-06-16

    申请号：US15047792

    申请日：2016-02-19

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

    IPC: A61M5/162 ,  A61M5/148 ,  A61M5/158 ,  A61M5/145

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有带有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了填充有药物产品的封闭的无菌容器，其包括粒细胞集落刺激因子 （G-CSF）。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

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