Systems and devices for generating nitric oxide

    公开(公告)号:US12171948B2

    公开(公告)日:2024-12-24

    申请号:US18353436

    申请日:2023-07-17

    Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.

    DUAL SENSOR FEEDBACK CONTROL SYSTEM FOR NITRIC OXIDE DOSING

    公开(公告)号:US20240226490A9

    公开(公告)日:2024-07-11

    申请号:US18491463

    申请日:2023-10-20

    CPC classification number: A61M16/12 A61M16/0003 A61M16/024 A61M2202/0275

    Abstract: Disclosed herein is a system for delivering a nitric oxide to a subject, wherein the system comprises: (a) a nitric oxide injection line configured to inject a first gas at an injection point into a breathing conduit comprising a breathing gas, wherein the first gas comprises a first amount of nitric oxide; (b) a sampling line configured to sample a second gas comprising a second amount of nitric oxide and the breathing gas at a sampling location between the injection point of the first gas and a subject and (c) a feedback-loop controller that is in communication with: (i) a nitric oxide set-point controller configured to set a nitric oxide set-point amount; (ii) a source configured to provide a third gas having a third amount of nitric oxide; and (iii) at least one sensor configured to measure the second amount of nitric oxide in the sampling line.

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