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102 条记录 (耗时 0.028 秒)

    Plasma Thruster With Birdcage Antenna
    24.
    发明公开
    Plasma Thruster With Birdcage Antenna 审中-公开

    公开(公告)号：US20230182929A1

    公开(公告)日：2023-06-15

    申请号：US18077291

    申请日：2022-12-08

    申请人： Universität Stuttgart

    发明人： Francesco ROMANO ,  Yung-An CHAN ,  Georg HERDRICH ,  Stefanos FASOULAS

    IPC分类号： B64G1/40 ,  H05H1/54 ,  G01R33/34

    CPC分类号： B64G1/405 ,  H05H1/54 ,  G01R33/34076 ,  H05H2245/00 ,  B33Y80/00

    摘要： A plasma thruster comprises a cylindrical discharge channel (1), an injector (4), a RF antenna surrounding the discharge channel (1) and a device (3) for generating an axial static magnetic field in the discharge channel (1). The RF antenna is a cylindrical birdcage antenna (2) formed of several electrically conductive parallel legs (10) connected by two end rings (11) including capacitors (12) between adjacent legs (10) in each case. The two end rings (11) with the capacitors (12) are formed on two printed circuit boards (14) to which the legs (10) are attached, said printed circuit boards (14) having a through opening for the discharge channel (1). The antenna maximizes electrical coupling efficiency and provides resulting electromagnetic fields for quasi-neutral plasma acceleration along with the magnetic field effect provided by the externally applied magnetic field. This plasma thruster allows an easy upscaling or downscaling due to the printed circuit boards and is particularly suitable for low power applications like propulsion for smaller spacecrafts or satellites.

    Antigen binding protein against HER3
    26.
    发明授权
    Antigen binding protein against HER3 有权

    公开(公告)号：US11008402B2

    公开(公告)日：2021-05-18

    申请号：US16326864

    申请日：2017-09-15

    申请人： UNIVERSITÄT STUTTGART

    发明人： Roland Kontermann ,  Lisa Schmitt ,  Meike Hutt ,  Oliver Seifert ,  Monilola Olayioye ,  Michael Hust ,  Stefan Dübel ,  Jonas Zantow

    IPC分类号： A61K39/00 ,  C07K16/32 ,  C07K16/28 ,  C07K16/30 ,  A61P35/00 ,  A61K39/395

    摘要： The invention provides an antigen-binding protein that specifically binds to a conformational epitope formed by domain III & IV of human epidermal growth factor receptor 3 (HER3) and antigen-binding proteins which compete therewith for binding, as well as fusion protein or conjugate comprising these. The invention also provides nucleic acid molecule comprising a sequence encoding said antigen binding proteins, vectors comprising the nucleic acid, and cells and pharmaceuticals comprising the antigen binding protein, the fusion protein, the nucleic acid, or the vector. The invention also provides the antigen binding protein, the fusion protein or conjugate, the nucleic acid, the vector, the cell, or the pharmaceutical for use as a medicament. The invention further provides a method of inhibiting tumor growth or treating cancer, comprising administering a therapeutically effective amount of the antigen binding protein, the fusion protein or conjugate, the nucleic acid, the vector, the cell, or the pharmaceutical.

    Optical module, laser amplifier system, method and use
    29.
    发明授权
    Optical module, laser amplifier system, method and use 有权

    公开(公告)号：US10574024B2

    公开(公告)日：2020-02-25

    申请号：US15494102

    申请日：2017-04-21

    申请人： Universität Stuttgart

    发明人： Stefan Piehler ,  Benjamin Dannecker ,  Jan-Philipp Negel ,  André Loescher

    IPC分类号： H01S3/23 ,  H01S3/00 ,  H01S3/06

    摘要： The present invention relates to an optical module configured to be optically coupleable to a laser amplifier module, the optical module comprising an inner optical element having a plurality of M inner reflective elements arranged around a center of the inner optical element; and a plurality of N outer reflective elements arranged around the inner optical element, the plurality of N outer reflective elements being configured to face the inner optical element, wherein the plurality of M inner reflective elements and the plurality of N outer reflective elements are configured to provide an optical path for a laser beam.

    Single-chain tumor necrosis factor (TNF) ligand family molecules, fusion proteins and derivatives thereof
    30.
    发明授权
    Single-chain tumor necrosis factor (TNF) ligand family molecules, fusion proteins and derivatives thereof 有权

    公开(公告)号：US10428149B2

    公开(公告)日：2019-10-01

    申请号：US15558372

    申请日：2016-03-18

    申请人： UNIVERSITÄT STUTTGART ,  BIONTECH AG

    发明人： Ugur Sahin ,  Roland Kontermann ,  Klaus Pfizenmaier ,  Martin Siegemund ,  Meike Hutt ,  Oliver Seifert

    IPC分类号： C07K16/32 ,  C07K16/28 ,  C07K14/705

    摘要： The present invention relates to a polypeptide comprising a component A with at least three tumor necrosis factor (TNF) homology domains of TNF-ligand family members (THD) in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof, and a component B comprising a dimerization domain. Further, the present invention relates to a polypeptide comprising at least three THDs in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof. Further, the invention relates to a nucleic acid comprising said polypeptides, a vector comprising said nucleic acid and a pharmaceutical composition comprising said polypeptides, or said nucleic acids or said vector. Further, the present invention relates to said polypeptides, said nucleic acid or said vector for the use as a medicament or for the use in the diagnosis, prophylaxis or treatment of hyperproliferative disorders and inflammatory disorders.