公开(公告)号：US10258580B2

公开(公告)日：2019-04-16

申请号：US14128208

申请日：2012-06-29

申请人： Teresa Iuvone ,  Vincenzo Di Marzo ,  Geoffrey Guy ,  Stephen Wright ,  Colin Stott

发明人： Teresa Iuvone ,  Vincenzo Di Marzo ,  Geoffrey Guy ,  Stephen Wright ,  Colin Stott

IPC分类号： A61K31/05 ,  A61K31/352 ,  A61K31/192

摘要： The present invention relates to cannabinoids for use in the prevention or treatment of neurodegenerative diseases or disorders. Preferably the cannabinoids are cannabichromene (CBC) cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA). More preferably the neurodegenerative disease or disorder to be prevented or treated is Alzheimer's disease.

公开(公告)号：US20160015682A2

公开(公告)日：2016-01-21

申请号：US14358861

申请日：2012-11-20

申请人： Michael Cawthorne ,  Colin Stott ,  Stephen Wright

发明人： Michael Cawthorne ,  Colin Stott ,  Stephen Wright

IPC分类号： A61K31/352 ,  A61K45/06 ,  A61K31/4439 ,  A61K36/185

CPC分类号： A61K31/352 ,  A61K31/155 ,  A61K31/4439 ,  A61K36/185 ,  A61K45/06 ,  A61P3/10 ,  A61K2300/00

摘要： The present invention relates to the phytocannabinoid tetrahydrocannabivarin (THCV) for use in the protection of pancreatic islet cells. Preferably the pancreatic islet cells to be protected are beta cells. More preferably the protection of the pancreatic islet cells maintains insulin production at levels which are able to substantially control or improve control of blood glucose levels in a patient.

摘要翻译： 本发明涉及用于保护胰岛细胞的植物花大麻素四氢大戟素（THCV）。 优选地，待保护的胰岛细胞是β细胞。 更优选地，胰岛细胞的保护将胰岛素产生维持在能够基本上控制或改善对患者血糖水平的控制的水平。

公开(公告)号：US08892680B2

公开(公告)日：2014-11-18

申请号：US13013649

申请日：2011-01-25

申请人： Stephen Wright ,  Robert Logue

发明人： Stephen Wright ,  Robert Logue

IPC分类号： G06F15/16 ,  H04L29/08 ,  G06F17/30

CPC分类号： G06F17/30902 ,  H04L29/0809 ,  Y10S705/901

摘要： A system and method for allowing requests generated as a result of dynamic URLs to be efficiently looked up in a cache are provided. The system and method involve receiving a request for a content element, the request being generated from a dynamic URL. A static content element identifier is generated from the request. In an embodiment, the static content element identifier includes only the content identification parameters and the dynamic parameters are removed. The static content element identifier is then used to determine whether the content element is in the cache.

摘要翻译： 提供了一种用于允许在动态URL中生成的请求被有效地查找在高速缓存中的系统和方法。 该系统和方法包括接收对内容元素的请求，该请求是从动态URL生成的。 从请求生成静态内容元素标识符。 在一个实施例中，静态内容元素标识符仅包括内容标识参数，并且移除动态参数。 然后使用静态内容元素标识符来确定内容元素是否在高速缓存中。

公开(公告)号：US08782165B2

公开(公告)日：2014-07-15

申请号：US13014017

申请日：2011-01-26

申请人： Paul Fee ,  Stephen Wright ,  Declan Harrison

发明人： Paul Fee ,  Stephen Wright ,  Declan Harrison

IPC分类号： G06F15/16

CPC分类号： H04N21/2343 ,  H04N21/222 ,  H04N21/234309 ,  H04N21/234363 ,  H04N21/234381 ,  H04N21/24 ,  H04N21/2402 ,  H04N21/25808 ,  H04N21/26216 ,  H04N21/64707 ,  H04N21/64738 ,  H04N21/64746 ,  H04N21/64769 ,  H04N21/8358 ,  H04W88/181

摘要： Methods and transcoding proxies for transcoding media streams are described. In one embodiment, a method for transcoding a media stream that is delivered to an end-user device over a communications network involves selecting a transcoding technique for the media stream, transcoding a portion of the media stream using the selected transcoding technique, streaming the transcoded portion of the media stream to the end-user device, while the transcoded portion of the media stream is being streamed to the end-user device, detecting a change in a condition of the communications network, selecting a different transcoding technique in response to the change in the condition of the communications network, transcoding a subsequent portion of the media stream using the different transcoding technique, and streaming the transcoded subsequent portion of the media stream to the end-user device. Other embodiments are also described.

摘要翻译： 描述用于代码转换媒体流的方法和代码转换代理。 在一个实施例中，用于对通过通信网络递送到最终用户设备的媒体流进行代码转换的方法包括选择用于媒体流的代码转换技术，使用所选择的转码技术对媒体流的一部分进行代码转换，将转码 媒体流的一部分到终端用户设备，而媒体流的代码转换部分正被流式传输到最终用户设备，检测通信网络的状况变化，响应于该通信网络选择不同的代码转换技术 改变通信网络的状态，使用不同的代码转换技术对媒体流的后续部分进行代码转换，并将媒体流的经转码的后续部分流传送到最终用户设备。 还描述了其它实施例。

公开(公告)号：US07983387B1

公开(公告)日：2011-07-19

申请号：US12582359

申请日：2009-10-20

申请人： Chin Hoi Toh ,  Rodney Stephen Wright ,  James E. Engel

发明人： Chin Hoi Toh ,  Rodney Stephen Wright ,  James E. Engel

IPC分类号： G01N23/04 ,  G01N23/201 ,  G01B15/02

CPC分类号： G01N23/203

摘要： The different advantageous embodiments provide a system for identifying a likelihood of detecting objects with a backscatter x-ray system comprising a structure having a number of objects, a plurality of databases, and a processor unit configured to execute a detection analysis process. The processor unit executes the detection analysis process to identify the number of objects, identify a number of densities associated with each of the number of objects, determine a likelihood of detecting each of the number of objects with the backscatter x-ray system, and generate a three-dimensional diagram of the likelihood of detecting each of the number of objects.

摘要翻译： 不同的有利实施例提供了一种用于使用包括具有多个对象，多个数据库和被配置为执行检测分析处理的处理器单元的结构的后向散射X射线系统来识别检测对象的可能性的系统。 处理器单元执行检测分析处理以识别对象的数量，识别与每个对象数量相关联的密度的数量，使用后向散射X射线系统确定检测每个对象的每一个的可能性，并且生成 检测每一个对象的可能性的三维图。

公开(公告)号：US20090304167A1

公开(公告)日：2009-12-10

申请号：US12136573

申请日：2008-06-10

申请人： Stephen WRIGHT ,  Stuart Langham ,  Hinal K. Balia

发明人： Stephen WRIGHT ,  Stuart Langham ,  Hinal K. Balia

IPC分类号： H04M1/56

CPC分类号： H04M3/436 ,  H04M1/663 ,  H04M1/72583 ,  H04M3/42059 ,  H04M3/42102 ,  H04M2203/2011

摘要： A method may include receiving, from a network, a call request in a communication device, the call request including an identification of a calling party; notifying a user of the communication device of the call request; receiving an indication to deny the call request; prompting the user of the communication device, in response to receiving the indication to deny the call request, regarding automatically denying call requests having the identification of the calling party; receiving, from the user, an indication to deny call requests having the identification of the calling party; and sending an instruction to the network to automatically deny the call requests having the identification of the calling party.

摘要翻译： 一种方法可以包括从网络接收通信设备中的呼叫请求，所述呼叫请求包括呼叫方的标识; 向通信装置的用户通知呼叫请求; 接收拒绝呼叫请求的指示; 响应于接收到拒绝呼叫请求的指示，提示通信装置的用户关于自动拒绝具有主叫方的标识的呼叫请求; 从用户接收拒绝具有呼叫方标识的呼叫请求的指示; 并向网络发送指令以自动拒绝具有呼叫方标识的呼叫请求。

公开(公告)号：US20070262591A1

公开(公告)日：2007-11-15

申请号：US11714076

申请日：2007-03-05

申请人： Stephen Wright ,  Nigel Spurr

发明人： Stephen Wright ,  Nigel Spurr

IPC分类号： E05C3/16

CPC分类号： E05B77/04 ,  E05B63/0004 ,  E05B63/0052 ,  E05B79/20 ,  E05B83/36 ,  E05B83/38 ,  E05B83/40 ,  Y10T292/1047

摘要： A latch system for an aperture closure includes a latch, an auxiliary retention device remote from the latch, an engaging member remote from the auxiliary retention device and a transmission path operably connecting the engaging member with the auxiliary retention device. The latch system is arranged such that movement of the aperture closure from an open position to a closed position causes the latch to move to the closed position and causes movement of the engaging member to cause the transmission path to move the auxiliary retention device to a closed position.

摘要翻译： 用于孔盖的闩锁系统包括闩锁，远离闩锁的辅助保持装置，远离辅助保持装置的接合构件和可操作地将接合构件与辅助保持装置连接的传动路径。 闩锁系统布置成使得孔盖从打开位置移动到关闭位置使得闩锁移动到关闭位置并且引起接合构件的移动，以使传动路径将辅助保持装置移动到闭合位置 位置。

公开(公告)号：US20070234212A1

公开(公告)日：2007-10-04

申请号：US11395077

申请日：2006-03-31

申请人： Jeremy de Souza ,  Pravin Santiago ,  Stephen Wright

发明人： Jeremy de Souza ,  Pravin Santiago ,  Stephen Wright

IPC分类号： G06F17/00 ,  G06F9/00

CPC分类号： G06F3/0481

摘要： Described is the selective exclusion of content returned in a requested screen capture operation, wherein exclusion may be determined by a window category and the requesting application program. For example, a magnification program will not received content captured from its own layered window or from any other layered magnification windows. A registration mechanism obtains and maintains a window handle for any window registered for exclusion. A screen capture mechanism uses the information to determine whether to exclude the content of windows when returning the captured screen content. Exclusion may be accomplished by enumerating areas that are not covered by any layered window and copying those areas to a screen representation buffer or the like, and separately enumerating areas that are covered by at least one layered window. A covered area is only copied to the screen representation when it does not correspond to an excluded window.

摘要翻译： 描述了在请求的屏幕捕获操作中返回的内容的选择性排除，其中排除可以由窗口类别和请求应用程序确定。 例如，放大程序将不会收到从其自己的分层窗口或任何其他分层放大窗口捕获的内容。 注册机制获得并维护注册排除的任何窗口的窗口句柄。 屏幕捕获机制使用该信息来确定在返回捕获的屏幕内容时是否排除Windows的内容。 排除可以通过枚举未被任何分层窗口覆盖的区域并将这些区域复制到屏幕表示缓冲区等来实现，并且分别列举由至少一个分层窗口覆盖的区域。 覆盖区域仅在不对应于排除窗口时才复制到屏幕表示。

公开(公告)号：US20070229519A1

公开(公告)日：2007-10-04

申请号：US11395041

申请日：2006-03-31

申请人： Jeremy de Souza ,  Pravin Santiago ,  Stephen Wright

发明人： Jeremy de Souza ,  Pravin Santiago ,  Stephen Wright

IPC分类号： G06T1/00

CPC分类号： G06F9/4411 ,  G06F9/451

摘要： Described is a technology including a mechanism a mechanism that when activated, detects a call to a device independent bitmap. An appropriate mirror driver, such as one or more registered as an accessibility driver, may then be notified of the call. The mechanism may be activated upon creation or selection of the device independent bitmap, and may comprise a wrapper/driver that, from the perspective of the mirror driver, simulates a call to a device dependent bitmap. The notification may be performed by having the driver communicate a function call that emulates a drawing primitive to the mirror driver.

摘要翻译： 描述了一种技术，其包括机制，当被激活时，检测到对设备无关位图的调用。 然后可以通知适当的镜像驱动器，诸如登记为可访问性驱动器的一个或多个镜像驱动器。 可以在创建或选择设备无关位图时激活机制，并且可以包括从镜像驱动器的角度模拟对设备依赖位图的调用的包装器/驱动器。 该通知可以通过使驱动器将模拟图形原语的函数调用器传达给镜像驱动器来执行。

公开(公告)号：US20060171883A1

公开(公告)日：2006-08-03

申请号：US10530736

申请日：2003-10-10

申请人： Catherine Phillips ,  Stephen Wright

发明人： Catherine Phillips ,  Stephen Wright

IPC分类号： A61K51/00 ,  G01N33/567

CPC分类号： A61K51/1203 ,  G01N33/5091 ,  G01N2800/52

摘要： A Disclosed are methods for detecting and localizing a cell-specific antigen in a mammal, such as a human subject, comprising exposing peripheral blood mononuclear cells (PBMCs) of the mammal to an immunogenic peptide epitope of the antigen, under conditions for antigen-specific activation of T lymphocytes in the PBMCs, thereby producing antigen-specific T lymphocytes that at least bind to the cell-specific antigen. Labeled antigen-specific T lymphocytes are administered to the mammal, typically with-out IL-2, either intraperitoneally or intravenously. The distribution of these cells in the mammal is determined by imaging, thereby detecting and localizing cell-specific antigen in the mammal. Exposing PBMCs to the immunogenic peptide typically involves a cell-free peptide preparation and interleukin-2 (IL-2), but no additional cells such as antigen presenting cells (APC) separately pulsed with antigen. The antigen-specific T lymphocytes typically are cytolytic for cells expressing the cell-specific antigen and may comprise CD4+, CD8+, and/or CD45RO+ memory T cells.

摘要翻译： A公开了用于检测和定位哺乳动物（例如人受试者）中的细胞特异性抗原的方法，其包括将哺乳动物的外周血单核细胞（PBMC）暴露于抗原的免疫原性肽表位，在抗原特异性条件下 活化PBMC中的T淋巴细胞，从而产生至少与细胞特异性抗原结合的抗原特异性T淋巴细胞。 标记的抗原特异性T淋巴细胞通常腹膜内或静脉内给予哺乳动物，通常不含IL-2。 通过成像确定这些细胞在哺乳动物中的分布，从而检测和定位哺乳动物细胞特异性抗原。 将PBMC暴露于免疫原性肽通常涉及无细胞肽制剂和白细胞介素-2（IL-2），但不包括分别用抗原脉冲的其它细胞例如抗原呈递细胞（APC）。 抗原特异性T淋巴细胞通常对表达细胞特异性抗原的细胞是细胞溶解的，并且可以包含CD4 +，CD8 +和/或CD45RO +记忆T细胞。