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公开(公告)号：US09895342B2
公开(公告)日：2018-02-20
申请号：US14118563
申请日：2012-05-18
申请人： Sabatino Maione , Francesco Rossi , Geoffrey Guy , Colin Stott , Tetsuro Kikuchi
发明人： Sabatino Maione , Francesco Rossi , Geoffrey Guy , Colin Stott , Tetsuro Kikuchi
IPC分类号： A61K31/05 , A61K31/352
CPC分类号： A61K31/352 , A61K31/05
摘要： The present invention relates to cannabinoids for use in the treatment of neuropathic pain. Preferably the cannabinoids are one or more phytocannabinoids of: cannabigerol (CBG), cannabichromene (CBC), cannabidivarin (CBDV) or tetrahydrocannabivarin (THCV). More preferably the phytocannabinoids are isolated and/or purified from cannabis plant extracts.
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公开(公告)号：US10258580B2
公开(公告)日：2019-04-16
申请号：US14128208
申请日：2012-06-29
申请人： Teresa Iuvone , Vincenzo Di Marzo , Geoffrey Guy , Stephen Wright , Colin Stott
发明人： Teresa Iuvone , Vincenzo Di Marzo , Geoffrey Guy , Stephen Wright , Colin Stott
IPC分类号： A61K31/05 , A61K31/352 , A61K31/192
摘要： The present invention relates to cannabinoids for use in the prevention or treatment of neurodegenerative diseases or disorders. Preferably the cannabinoids are cannabichromene (CBC) cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA). More preferably the neurodegenerative disease or disorder to be prevented or treated is Alzheimer's disease.
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3.发明申请TETRAHYDROCANNABIVARIN (THCV) FOR USE IN THE PROTECTION OF PANCREATIC ISLET CELLS 审中-公开四氯胞嘧啶（THCV）用于保护胰岛细胞公开(公告)号：US20160015682A2
公开(公告)日：2016-01-21
申请号：US14358861
申请日：2012-11-20
申请人： Michael Cawthorne , Colin Stott , Stephen Wright
发明人： Michael Cawthorne , Colin Stott , Stephen Wright
IPC分类号： A61K31/352 , A61K45/06 , A61K31/4439 , A61K36/185
CPC分类号： A61K31/352 , A61K31/155 , A61K31/4439 , A61K36/185 , A61K45/06 , A61P3/10 , A61K2300/00
摘要： The present invention relates to the phytocannabinoid tetrahydrocannabivarin (THCV) for use in the protection of pancreatic islet cells. Preferably the pancreatic islet cells to be protected are beta cells. More preferably the protection of the pancreatic islet cells maintains insulin production at levels which are able to substantially control or improve control of blood glucose levels in a patient.
摘要翻译： 本发明涉及用于保护胰岛细胞的植物花大麻素四氢大戟素（THCV）。 优选地，待保护的胰岛细胞是β细胞。 更优选地，胰岛细胞的保护将胰岛素产生维持在能够基本上控制或改善对患者血糖水平的控制的水平。
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公开(公告)号：US09017737B2
公开(公告)日：2015-04-28
申请号：US12811393
申请日：2008-12-17
申请人： Tetsuro Kikuchi , Kenji Maeda , Geoffrey Guy , Philip Robson , Colin Stott
发明人： Tetsuro Kikuchi , Kenji Maeda , Geoffrey Guy , Philip Robson , Colin Stott
IPC分类号： A61K36/00 , A61K45/06 , A61K31/05 , A61K31/35 , A61K31/352 , A61K36/185
CPC分类号： A61K45/06 , A61K31/05 , A61K31/35 , A61K31/352 , A61K36/185 , A61K2300/00
摘要： The present invention relates to the use of one or more cannabinoids in combination with one or more anti-psychotic medicaments for use in the prevention or treatment of psychosis and psychotic disorders. Preferably the one or more cannabinoids are taken from the group: cannabidiol (CBD); cannabidiolic acid (CBDA); tetrahydrocannbidivarin (THCV); tetrahydrocannbidivarinin acid (THCVA); cannabichromene (CBC); cannabichromenic acid (CBCA); cannabigerol (CBG) and cannabigerolic acid (CBGA). Preferably the anti-psychotic medication is an atypical anti-psychotic medication.
摘要翻译： 本发明涉及一种或多种大麻素与一种或多种抗精神病药物组合用于预防或治疗精神病和精神病性障碍的用途。 优选地，一种或多种大麻素取自组：大麻二酚（CBD）; 大辛二酸（CBDA）; 四氢甘比亚胺（THCV）; 四氢甘比亚肝素（THCVA）; 大麻染色体（CBC）; 大麻黄酸（CBCA）; 大麻酚（CBG）和大麻酚酸（CBGA）。 优选地，抗精神病药物是非典型的抗精神病药物。
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公开(公告)号：US08790719B2
公开(公告)日：2014-07-29
申请号：US13634343
申请日：2011-03-11
申请人： Daniela Parolaro , Paola Massi , Angelo Antonio Izzo , Francesca Borelli , Gabriella Aviello , Vincenzo Di Marzo , Luciano De Petrocellis , Aniello Schiano Moriello , Alessia Ligresti , Ruth Alexandra Ross , Lesley Ann Ford , Sharon Anavi-Goffer , Manuel Guzman , Guillermo Velasco , Mar Lorente , Sofia Torres , Tetsuro Kikuchi , Geoffrey Guy , Colin Stott , Stephen Wright , Alan Sutton , David Potter , Etienne De Meijer
发明人： Daniela Parolaro , Paola Massi , Angelo Antonio Izzo , Francesca Borelli , Gabriella Aviello , Vincenzo Di Marzo , Luciano De Petrocellis , Aniello Schiano Moriello , Alessia Ligresti , Ruth Alexandra Ross , Lesley Ann Ford , Sharon Anavi-Goffer , Manuel Guzman , Guillermo Velasco , Mar Lorente , Sofia Torres , Tetsuro Kikuchi , Geoffrey Guy , Colin Stott , Stephen Wright , Alan Sutton , David Potter , Etienne De Meijer
IPC分类号： A01N65/00
CPC分类号： A61K36/185 , A61K31/01 , A61K31/015 , A61K31/05 , A61K31/192 , A61K31/337 , A61K31/352 , A61K31/495 , A61K45/06 , A61K2300/00
摘要： This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.
摘要翻译： 本发明涉及在治疗癌症中以分离形式或以植物药物物质（BDS）的形式使用植物大麻素。 优选地，待治疗的癌症是前列腺癌，乳腺癌或结肠癌。
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公开(公告)号：US20130059018A1
公开(公告)日：2013-03-07
申请号：US13634343
申请日：2011-03-11
申请人： Daniela Parolaro , Paola Massi , Angelo Antonio Izzo , Francesca Borelli , Gabriella Aviello , Vincenzo Di Marzo , Luciano De Petrocellis , Aniello Schiano Moriello , Alessia Ligresti , Ruth Alexandra Ross , Lesley Ann Ford , Sharon Anavi-Goffer , Manuel Guzman , Guillermo Velasco , Mar Lorente , Sofia Torres , Tetsuro Kikuchi , Geoffrey Guy , Colin Stott , Stephen Wright , Alan Sutton , David Potter , Etienne De Meijer
发明人： Daniela Parolaro , Paola Massi , Angelo Antonio Izzo , Francesca Borelli , Gabriella Aviello , Vincenzo Di Marzo , Luciano De Petrocellis , Aniello Schiano Moriello , Alessia Ligresti , Ruth Alexandra Ross , Lesley Ann Ford , Sharon Anavi-Goffer , Manuel Guzman , Guillermo Velasco , Mar Lorente , Sofia Torres , Tetsuro Kikuchi , Geoffrey Guy , Colin Stott , Stephen Wright , Alan Sutton , David Potter , Etienne De Meijer
IPC分类号： A61K36/185 , A61K31/05 , A61K31/192 , A61P1/00 , A61K31/357 , A61K31/443 , A61K31/4188 , A61P35/00 , A61K31/352 , A61K31/337
CPC分类号： A61K36/185 , A61K31/01 , A61K31/015 , A61K31/05 , A61K31/192 , A61K31/337 , A61K31/352 , A61K31/495 , A61K45/06 , A61K2300/00
摘要： This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.
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7.发明申请CANNABINOIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES OR DISORDERS 审中-公开用于治疗神经病变性疾病或疾病的CANNABINOIDS公开(公告)号：US20140228438A1
公开(公告)日：2014-08-14
申请号：US14128208
申请日：2012-06-29
申请人： Teresa Iuvone , Vincenzo Di Marzo , Geoffrey Guy , Stephen Wright , Colin Stott
发明人： Teresa Iuvone , Vincenzo Di Marzo , Geoffrey Guy , Stephen Wright , Colin Stott
IPC分类号： A61K31/05
CPC分类号： A61K31/05 , A61K31/192 , A61K31/352
摘要： The present invention relates to cannabinoids for use in the prevention or treatment of neurodegenerative diseases or disorders. Preferably the cannabinoids are cannabichromene (CBC) cannabidivarin (CBDV) and/or cannabidivarin acid (CBDVA). More preferably the neurodegenerative disease or disorder to be prevented or treated is Alzheimer's disease.
摘要翻译： 本发明涉及用于预防或治疗神经变性疾病或病症的大麻素。 大麻素优选为大麻素（CBC）大麻素（CBDV）和/或大麻脂肪酸（CBDVA）。 更优选地，要预防或治疗的神经变性疾病或病症是阿尔茨海默氏病。
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8.发明申请公开(公告)号：US20110038958A1
公开(公告)日：2011-02-17
申请号：US12811393
申请日：2008-12-17
申请人： Tetsuro Kikuchi , Kenji Maeda , Geoffrey Guy , Philip Robson , Colin Stott
发明人： Tetsuro Kikuchi , Kenji Maeda , Geoffrey Guy , Philip Robson , Colin Stott
IPC分类号： A61K36/185 , A61K31/352 , A61K31/05 , A61K31/496 , A61P25/18 , A61P25/24
CPC分类号： A61K45/06 , A61K31/05 , A61K31/35 , A61K31/352 , A61K36/185 , A61K2300/00
摘要： The present invention relates to the use of one or more cannabinoids in combination with one or more anti-psychotic medicaments for use in the prevention or treatment of psychosis and psychotic disorders. Preferably the one or more cannabinoids are taken from the group: cannabidiol (CBD); cannabidiolic acid (CBDA); tetrahydrocannbidivarin (THCV); tetrahydrocannbidivarinin acid (THCVA); cannabichromene (CBC); cannabichromenic acid (CBCA); cannabigerol (CBG) and cannabigerolic acid (CBGA). Preferably the anti-psychotic medication is an atypical anti-psychotic medication.
摘要翻译： 本发明涉及一种或多种大麻素与一种或多种抗精神病药物组合用于预防或治疗精神病和精神病性障碍的用途。 优选地，一种或多种大麻素取自组：大麻二酚（CBD）; 大辛二酸（CBDA）; 四氢甘比亚胺（THCV）; 四氢甘比亚肝素（THCVA）; 大麻染色体（CBC）; 大麻黄酸（CBCA）; 大麻酚（CBG）和大麻酚酸（CBGA）。 优选地，抗精神病药物是非典型的抗精神病药物。
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