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公开(公告)号：US20210077728A1
公开(公告)日：2021-03-18
申请号：US17025768
申请日：2020-09-18
摘要： A needle-free injector includes a housing, a cartridge positioned within the housing, and a plunger slidably coupled to and disposed within the chamber, a motor operatively coupled to the plunger, the motor operable to actuate the plunger in the chamber, and a controller operatively coupled to the motor. Methods of delivering an injectate using the needle-free injectors are provided. Methods of facilitating needle-free injection of a fluid using the needle-free injectors are also provided.
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公开(公告)号：US10857298B2
公开(公告)日：2020-12-08
申请号：US16573464
申请日：2019-09-17
发明人： Robert J. Dyer , Carl Tappan , Eric VanWyk
摘要： An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.
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公开(公告)号：US10850038B2
公开(公告)日：2020-12-01
申请号：US16573391
申请日：2019-09-17
发明人： Robert J. Dyer , Carl Tappan , Eric VanWyk
摘要： An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.
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公开(公告)号：US20200368437A1
公开(公告)日：2020-11-26
申请号：US16989244
申请日：2020-08-10
发明人： Andrew Coats , Robert J. Dyer
摘要： An apparatus for use in injectate delivery includes an actuator including a linkage, a force generating mechanism mechanically coupled to the linkage, and a controller coupled to the force generating mechanism. The force generating mechanism includes a passive force generator and an active force generator. In operation and on the basis of a control signal, the controller is configured to control the force generating mechanism to provide an input force to the linkage that is a combination of the first force provided by the passive force generator and a second force provided by the active force generator.
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公开(公告)号：US10159793B2
公开(公告)日：2018-12-25
申请号：US14788001
申请日：2015-06-30
摘要： An exemplary embodiment of the invention is a nozzle, for use in an injection device, that projects material at an ultra-high velocity. The nozzle includes an integrally formed body having an interior passageway that has a longitudinal axis. The input of the nozzle is configured to interface with a cartridge, and the output is configured to be placed proximate to a target. The passageway includes a taper, and its path length, from an initial diameter to a position along the passageway where the passageway first reaches a smallest diameter, is at least 0.5 mm. The taper of the passageway defines a shape, in a plane that includes the longitudinal axis, that is a continuous and monotonically decreasing function of distance along the longitudinal axis in a direction of flow through the nozzle.
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公开(公告)号：US20180028755A1
公开(公告)日：2018-02-01
申请号：US15368145
申请日：2016-12-02
发明人： Mark Philip , Patrick Anquetil , Ian Hunter
IPC分类号： A61M5/30
CPC分类号： G16H40/60 , A61M2205/3584 , G16H30/40
摘要： A needle-free injector system includes a needle-free injector having at least one sensor configured to detect, using the at least one sensor, a degree to which a patient has administered a treatment using the needle-free injector, and configured to transmit information to a server regarding the administration of the treatment; and the server configured to communicate, to a device associated with the patient, a message regarding the administration of the treatment. A method of determining patient compliance with a treatment regimen includes detecting a potential treatment event by a needle-free injector system; measuring, using at least one sensor proximal to a treatment site on a body of a patient, at least one physical parameter; and determining, using the measurement of the at least one physical parameter, a level of compliance of the patient for the potential treatment event.
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公开(公告)号：US20170259000A1
公开(公告)日：2017-09-14
申请号：US15420185
申请日：2017-01-31
发明人： Robert J. Dyer , Andrew Coats , Nikolay Lapin
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/24 , A61M5/3007 , A61M5/3129 , A61M2005/2407 , A61M2005/2411 , A61M2005/2418 , A61M2005/2477 , A61M2005/2488 , A61M2205/02
摘要： An apparatus for transdermal injection includes a collet configured to transition between first and second states. In the first state, the collet receives a cartridge with a predetermined elongate shape. In the second state, an inner surface of the collet substantially conforms to the predetermined elongate shape of the cartridge such that expansion of the cartridge, when the cartridge is pressurized, is substantially uniformly opposed.
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公开(公告)号：US20230364341A1
公开(公告)日：2023-11-16
申请号：US18211971
申请日：2023-06-20
CPC分类号： A61M5/204 , A61M5/24 , A61M5/3134 , A61M5/31535 , A61M5/46 , A61M5/1409
摘要： A device for administering needle-free subcutaneous treatment to a patient comprises an actuator configured to deliver a plurality of volumes of a treatment at a plurality of locations on a body of the patient; at least one imaging device configured to detect a movement of the needle-free device from a first location on the body of the patient to a second location on the body of the patient; and a processor configured to determine the second location on the body of the device relative to the first location from the movement of the needle-free device relative to the first location on the body, the processor further configured to determine a volume of the plurality of volumes of the treatment to deliver to the body of the patient at the second location.
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公开(公告)号：USD926971S1
公开(公告)日：2021-08-03
申请号：US29679277
申请日：2019-02-04
设计人： Andrew Coats , Robert J. Dyer , Nickolay Lapin , Alan Xu
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公开(公告)号：US10918808B2
公开(公告)日：2021-02-16
申请号：US15454426
申请日：2017-03-09
发明人： Andrew Coats , Robert J. Dyer
摘要： An adapter for use with an injection device includes a first end, a second end and a first longitudinal axis extending from the first end and the second end. The adapter also includes a chamber defined by a sidewall between the first end and second end and a nozzle having a passageway extending through the sidewall, the passageway having an input at the chamber, an output at an outer surface of the body and a passageway axis extending from the input to the output, the passageway axis being angularly offset from the longitudinal axis of the channel. A cartridge can include such an adapter.
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