公开(公告)号：US08507420B2

公开(公告)日：2013-08-13

申请号：US12782855

申请日：2010-05-19

申请人： Atsushi Suzuki ,  Yasushi Kawata

发明人： Atsushi Suzuki ,  Yasushi Kawata

IPC分类号： C07F13/00 ,  B01F1/00 ,  C09K5/00 ,  C10L1/18

CPC分类号： C09K5/10 ,  C10L1/301 ,  C10M129/24 ,  C10M159/18 ,  C10M2207/08 ,  C10M2215/221 ,  C10M2215/223 ,  C10M2215/227 ,  C10N2210/08 ,  C10N2230/08 ,  C10N2230/10 ,  C10N2230/70

摘要： A solvent composition includes a substance that is subject to oxidative alteration by an oxygen radical, and a compound that has a superoxide dismutase-mimetic activity that includes oxygen radical-removing capability. In the solvent composition of the invention, oxygen radicals can be removed by the compound having an superoxide dismutase-mimetic activity that includes oxygen radical-removing capability, and therefore the substance that is subject to oxidative alteration can be prevented from oxidizing.

摘要翻译： 溶剂组合物包括经氧自由基氧化改性的物质和具有氧自由基去除能力的具有超氧化物歧化酶 - 模拟活性的化合物。 在本发明的溶剂组合物中，可以通过具有氧自由基去除能力的超氧化物歧化酶 - 模拟活性的化合物除去氧自由基，因此可以防止经历氧化改性的物质的氧化。

公开(公告)号：US20130184335A1

公开(公告)日：2013-07-18

申请号：US13809880

申请日：2011-06-28

申请人： Norimasa Miura

发明人： Norimasa Miura

IPC分类号： C07H21/02

CPC分类号： C12N15/113 ,  A61K31/7105 ,  A61K31/713 ,  C07H21/02 ,  C12N5/0696 ,  C12N15/111 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2320/30 ,  C12N2501/65 ,  A61K2300/00

摘要： A novel compound to induce a pluripotent stem cell is provided. A novel anti-malignant-tumor substance is provided. A pluripotent stem cell-inducing agent, including one or more single-stranded or double-stranded polynucleotides selected from the group consisting of: a) a single-stranded or double-stranded polynucleotide containing a sequence of SEQ ID NO:1 or a sequence including deletion, substitution, or addition of 1 to 3 bases in SEQ ID No: 1, b) a single-stranded or double-stranded polynucleotide containing a sequence of SEQ ID NO:2 or a sequence including deletion, substitution, or addition of 1 to 3 bases in SEQ ID No: 2, c) a single-stranded or double-stranded polynucleotide containing a sequence of SEQ ID NO:3 or a sequence including deletion, substitution, or addition of 1 to 3 bases in SEQ ID No: 3, in which the pluripotent stem cell-inducing agent induces a cell to become a pluripotent stem cell is provided.

摘要翻译： 提供了诱导多能干细胞的新型化合物。 提供了一种新的抗恶性肿瘤物质。 多能干细胞诱导剂，包括一个或多个选自以下的单链或双链多核苷酸：a）含有SEQ ID NO：1的序列的单链或双链多核苷酸或序列 包括在SEQ ID No：1中删除，取代或添加1至3个碱基，b）含有SEQ ID NO：2的序列的单链或双链多核苷酸或包括缺失，取代或添加的序列 SEQ ID No：2中的1至3个碱基，c）包含SEQ ID NO：3的序列的单链或双链多核苷酸或包含SEQ ID NO：3中1-3个碱基的缺失，取代或添加的序列 3，其中多能干细胞诱导剂诱导成为多能干细胞的细胞。

公开(公告)号：US20120216867A1

公开(公告)日：2012-08-30

申请号：US13504278

申请日：2010-10-25

申请人： Toshiyuki Ito ,  Yasunori Uetani

发明人： Toshiyuki Ito ,  Yasunori Uetani

IPC分类号： H01L51/46 ,  H01B1/12 ,  B82Y30/00 ,  B82Y99/00

CPC分类号： C07D487/04 ,  C07D209/56 ,  Y02E10/549

摘要： A fullerene derivative having two or more structures represented by the formula (1) can increase light absorption in a long wavelength range when used for an organic photovoltaic cell. In the formula (1), C1 and C2 represent carbon atoms constituting the fullerene skeleton. m represents an integer from 1 to 6, and n represents an integer from 1 to 4. p represents an integer of 0 or more, and R represents a monovalent organic group. Q represents a single bond, an arylene group, or a divalent heterocyclic group. When m is plurally present, these m may be the same or different from each other.

摘要翻译： 具有式（1）表示的两种以上结构的富勒烯衍生物可以在用于有机光伏电池时增加长波长范围的光吸收。 在式（1）中，C1和C2表示构成富勒烯骨架的碳原子。 m表示1〜6的整数，n表示1〜4的整数。p表示0以上的整数，R表示1价的有机基团。 Q表示单键，亚芳基或二价杂环基。 当m多重存在时，这些m可以相同或不同。

公开(公告)号：US20110001093A1

公开(公告)日：2011-01-06

申请号：US12677445

申请日：2008-09-11

申请人： Toshiyuki Itoh ,  Yasunori Uetani

发明人： Toshiyuki Itoh ,  Yasunori Uetani

IPC分类号： H01B1/12 ,  C07D487/00

CPC分类号： C07D209/96 ,  B82Y10/00 ,  C08K5/3417 ,  H01L51/0036 ,  H01L51/0047 ,  H01L51/4253 ,  Y02E10/549

摘要： Disclosed is an organic photoelectric converter having a layer containing a fullerene derivative represented by the formula (1) below. (In the formula (1), m represents an integer of 1-6; n represents an integer of 1-4; p represents an integer of 0-5; r represents an integer of 0-4; and Q represents a group represented by the formula (2) or (3) below. When there are a plurality of m's, they may be the same as or different from each other. In the formulae (2) and (3), R1 and R2 independently represent a halogen atom, an alkyl group, an alkoxy group or an aryl group, and a hydrogen atom contained in these groups may be substituted by a halogen atom; q represents an integer of 0-7; and v represents an integer of 0-5. When there are a plurality of R1's, they may be the same as or different from each other. When there are a plurality of R2's, they may be the same as or different from each other.)

摘要翻译： 公开了一种具有含有下式（1）表示的富勒烯衍生物的层的有机光电转换器。 （式（1）中，m表示1-6的整数，n表示1-4的整数，p表示0〜5的整数，r表示0〜4的整数，Q表示 在式（2）或（3）中，当有多个m时，它们可以相同或不同，在式（2）和（3）中，R 1和R 2独立地表示卤素 原子，烷基，烷氧基或芳基，这些基团中的氢原子可以被卤素原子取代; q表示0〜7的整数，v表示0〜5的整数，当 有多个R1，它们可以相同或不同，当有多个R2时，它们可以彼此相同或不同。）

公开(公告)号：US12060374B2

公开(公告)日：2024-08-13

申请号：US17433287

申请日：2020-02-04

申请人： National University Corporation Tottori University ,  Nisshinbo Holdings Inc.

发明人： Masato Nanjo ,  Gen Masuda

IPC分类号： C07F7/08 ,  H01G11/60 ,  H01M10/0567 ,  H01M10/0569

CPC分类号： C07F7/0838 ,  H01M10/0567 ,  H01M10/0569 ,  H01G11/60 ,  H01M2300/0045

摘要： Provided is a silyl ether-containing sulfonate salt that contains an anion represented by formula (1) and a cation.




(In the formula, R1 to R4 are each independently a C1-4 alkyl group. m is an integer from 1 to 3. n is an integer from 2 to 8.)

公开(公告)号：US20230407268A1

公开(公告)日：2023-12-21

申请号：US18251805

申请日：2021-11-05

申请人： Trans Chromosomics, Inc. ,  NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY

发明人： Mitsuo OSHIMURA ,  Toshiaki TABATA ,  Yasuhiro KAZUKI ,  Narumi UNO

IPC分类号： C12N5/10 ,  C12N15/86

CPC分类号： C12N5/10 ,  C12N15/86 ,  C12N2510/04 ,  C12N2760/18843

摘要： An object of the present invention is to provide a method for producing a reversibly immortalized cell which can allow a cell into which an immortalizing gene is introduced to proliferate over a long period without damaging the chromosome of the cell, and is capable of removing the immortalizing gene, and to provide a method for obtaining a large amount of a reversibly immortalized cell that can be cloned and has stable quality. The present invention provides a method for producing a reversibly immortalized cell, comprising the steps of: introducing a chromosomally non-integrated RNA virus vector loaded with one or two or more immortalizing gene(s), selected from the group consisting of Bmi-1 gene, TERT gene, and SV40T gene, into a mammalian cell so that the immortalizing gene is expressed in the cell; and culturing the obtained cell for proliferation.

公开(公告)号：US20210272478A1

公开(公告)日：2021-09-02

申请号：US17256171

申请日：2019-10-30

申请人： MICOTO Technology Inc. ,  NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY

发明人： Tomohiro SHIMODA ,  Masaaki MATSUOKA ,  Yasuaki HIYAMA ,  Masahiko YOSHIDA ,  Ren OTA ,  Masaru UEKI ,  Kazutake UEHARA ,  Masashi FUJII

IPC分类号： G09B23/30

摘要： A medical simulator includes: a luminal organ model having flexibility and having a shape that simulates at least one luminal organ, the luminal organ model including a constricted wall portion having a lumen cross-sectional area smaller than the lumen cross-sectional area of a periphery of the constricted wall portion, the constricted wall portion being provided in a first specific region including a portion corresponding to one end portion of one luminal organ or corresponding to a joining portion of two luminal organs; a first space formation portion that circumferentially covers at least an outer periphery of the first specific region of the luminal organ model to form a first sealed space at the outer periphery of the first specific region; and a fluid controller that controls a fluid pressure of a to-be-controlled fluid within the first sealed space to expand or contract the lumen cross-sectional area of the constricted wall portion of the luminal organ model.

公开(公告)号：US11065606B2

公开(公告)日：2021-07-20

申请号：US16758193

申请日：2018-10-25

申请人： Mitsui Mining & Smelting Co., Ltd. ,  NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY ,  NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY

发明人： Yoshihiro Kubota ,  Satoshi Inagaki ,  Naonobu Katada ,  Satoshi Suganuma ,  Yasuo Yamazaki ,  Takahiro Kogawa

IPC分类号： B01J29/76 ,  B01J37/30 ,  C01B39/46 ,  C01B39/02 ,  B01J29/72 ,  B01D53/86 ,  B01D53/94

摘要： The purpose of the present invention is to provide a metal-substituted beta zeolite that exhibits a more excellent catalytic performance than conventional one, and a method for producing the same. The present invention provides a metal-substituted beta zeolite by subjecting an alkali metal-form beta zeolite produced without using an organic structure-directing agent to ion exchange with ammonium ion and then, using a filter cake procedure, to ion exchange with copper ion or iron(II) ion. The present invention also provides a metal-substituted beta zeolite which has been ion exchanged with copper ion or iron(II) ion and in which the amount of Lewis acid sites is greater than the amount of Bronsted acid sites when the amount of Bronsted acid sites and the amount of Lewis acid sites are measured by ammonia infrared-mass spectroscopy temperature-programmed desorption on the as-produced state.

公开(公告)号：US20210115112A1

公开(公告)日：2021-04-22

申请号：US16972285

申请日：2019-05-30

申请人： KanonCure, Inc. ,  National University Corporation Tottori University

发明人： Yohei KONO ,  Noriko ITABA ,  Goshi SHIOTA

IPC分类号： C07K14/81 ,  A61K35/28 ,  C12N5/0775

摘要： [Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.

公开(公告)号：US10758427B2

公开(公告)日：2020-09-01

申请号：US15108463

申请日：2014-12-26

申请人： DAIO PAPER CORPORATION ,  NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY

发明人： Bin Nakayama ,  Yoshiko Suyama ,  Kaori Fujii ,  Nobutada Nishiura ,  Aya Ohshima

IPC分类号： A61F13/15 ,  A61F13/20 ,  A61F13/49 ,  A61F13/535 ,  A61F13/532

摘要： The present invention aims at providing a disposable diaper having excellent maintainability of a surface space and capable of being easily produced. It is characterized in that a lower layer absorbent body has, at least at center of a crotch portion in a width direction, an elongated lower layer through section piercing in a thickness direction and extending in a front-back direction; an upper layer absorbent body has an upper layer through section piercing in the thickness direction at least within a range corresponding to the lower layer through section in the front-back direction, the upper layer through section has an elongated middle section extending in the front-back direction so as to be located above the lower layer through section, and extending sections which extend, in the width direction, from both sides of a back side position of the middle section, and a side edge of the extending section has a shape in which at least a part of the front side thereof is located further outside in the width direction toward the back side.