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    Powder Compartment For High Dosage Drug Delivery
    14.
    发明申请
    Powder Compartment For High Dosage Drug Delivery 审中-公开

    公开(公告)号：US20180036497A1

    公开(公告)日：2018-02-08

    申请号：US15117571

    申请日：2016-04-28

    申请人： Hovione Technology Limited

    发明人： João Ventura ,  Peter Villax

    IPC分类号： A61M15/00 ,  A61K9/00

    CPC分类号： A61M15/002 ,  A61K9/0075 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0086 ,  A61M2202/064

    摘要： A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body 801 and a cartridge 803 with at least one powder compartment 805 including one dose of a drug. The body has an opening 804 shaped for receiving the cartridge 803 and the means to allow a controlled sliding movement of the cartridge 803 relative to the body 801 after mounting. The cartridge powder compartment 805 comprises at least two inlets or slits 806, 809, at least one of which is a side inlet 809, for the admission of air, and a compartment outlet 807 to allow filling and fluid communication with an inhalation channel 808 provided in the body 801. In use, the patient slides the cartridge 803 relative to the body 801 from the storage position, where the inlets in the cartridge powder compartment 805 are blocked and sealed by walls comprised in the body 801, into the inhalation position, where the compartment inlets become available for the admission of air used in the dispersion of the particles there contained and the compartment outlet 807 becomes aligned with the inhalation channel 808 in the body 801 to allow the entrainment of the dose dispersed through the device and into the desired site of action during inhalation. The addition of one or more lateral vents 809 in the cartridge powder compartments induces a turbulent and swirling flow pattern that promotes improved dispersion and entrainment. The invention affords a very economical and simple device for the delivery of high dosages of inhaled medicines.

    A POWDER INHALER DEVICE
    17.
    发明申请
    A POWDER INHALER DEVICE 审中-公开

    公开(公告)号：US20170128679A1

    公开(公告)日：2017-05-11

    申请号：US15321858

    申请日：2015-06-19

    申请人： Sergio BELFORTI

    发明人： Sergio BELFORTI

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0021 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0046 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2210/0625

    摘要： A powder inhaler device comprising a body provided with a housing (102) able to receive a dose of a medicinal substance, a channelling (3, 102) tangential to the housing provided with holes communicating with an external environment, a mouth-piece (101) communicating with the channeling and able to aspirate air from the external environment through the holes, generating a flow which on a pathway thereof involves the containing housing of the medicine, in which the body, the housing and the mouth piece form a single piece and single-use unit able to contain a single dose of medicine.

    Wearable Wrist Inhaler
    18.
    发明申请
    Wearable Wrist Inhaler 审中-公开

    公开(公告)号：US20170100551A1

    公开(公告)日：2017-04-13

    申请号：US15384632

    申请日：2016-12-20

    申请人： Kendra Baldwin

    发明人： Kendra Baldwin

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0025 ,  A61M11/04 ,  A61M11/08 ,  A61M15/0021 ,  A61M15/0043 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/008 ,  A61M15/009 ,  A61M2202/064 ,  A61M2205/8206 ,  A61M2209/088

    摘要： A wearable wrist inhaler includes a wristband having a first end and a second end configured for wear about a user's wrist. An inhaler unit is removably coupled to the wristband displaced from the first end and the second end, the inhaler unit including a housing having a plurality of walls defining an interior area and an outlet port in communication with the interior area. A watch assembly is positioned atop the housing of the inhaler unit, the watch assembly energized by a battery and includes a display configured to indicate a time of day. A dosage chamber including a medicament is positioned in the interior area of the housing. A dispensing assembly is communication with the inhaler medicament that is configured to dispense an individual portion of the medicament via the outlet port upon demand by a user.

    METHODS FOR CASCADING PURE ODORANTS TO THE NOSTRILS OF PATIENTS
    20.
    发明申请
    METHODS FOR CASCADING PURE ODORANTS TO THE NOSTRILS OF PATIENTS 有权
    将纯气味剂用于患者鼻涕的方法

    公开(公告)号：US20160249845A1

    公开(公告)日：2016-09-01

    申请号：US15094327

    申请日：2016-04-08

    申请人： INSPIRED TECHNOLOGIES, INC.

    发明人： Gregory B. Mills

    IPC分类号： A61B5/00 ,  A61M15/08

    CPC分类号： A61B5/4011 ,  A61B5/4088 ,  A61B5/7246 ,  A61B5/7282 ,  A61M15/0015 ,  A61M15/0016 ,  A61M15/0043 ,  A61M15/0048 ,  A61M15/08 ,  A61M2021/0016 ,  A61M2205/583

    摘要： The present system is directed in various embodiments to devices, systems and methods for detection, evaluation and/or monitoring olfactory dysfunction by measuring and determining the patient's olfactory detection threshold for the left and the right nostril. More specifically, the present invention relates to devices, systems and methods for detecting an asymmetric differential in a patient's olfactory detection threshold (left vs right nostril) which, when present, may be used as a tool to screen, detect, diagnose and/or monitor relative olfactory deterioration resulting from Alzheimer's disease. A preferred embodiment comprises cascading aromas by serially administering more than one pure odorant to the patient's nostrils, left vs right, with measurement of the time, or numbers of breaths, required to cognitively notice the pure odorants' presence.

    摘要翻译： 本系统通过测量和确定患者对左鼻孔和右鼻孔的嗅觉检测阈值在各种实施例中针对用于检测，评估和/或监测嗅觉功能障碍的装置，系统和方法。 更具体地，本发明涉及用于检测患者嗅觉检测阈值（左对右鼻孔）中的不对称差异的装置，系统和方法，当存在时，可以将其用作屏幕，检测，诊断和/或 监测由阿尔茨海默病引起的相对嗅觉恶化。 优选的实施方案包括通过连续施用多于一种纯味道剂向患者的鼻孔（左侧和右侧）连续施用级联的香味，以及认知地注意纯气味剂存在所需的时间或呼吸次数。