公开(公告)号：US20180002723A1

公开(公告)日：2018-01-04

申请号：US15548731

申请日：2016-02-11

申请人： ALMA MATER STUDIORUM UNIVERSITA' DI BOLOGNA

发明人： MARIA GABRIELLA CAMPADELLI ,  VALENTINA GATTA

IPC分类号： C12N15/869 ,  C12N5/10 ,  C12N15/62 ,  C12N7/00 ,  A61K39/00

摘要： The present invention relates to the field of disease therapy. More specifically, it relates to a retargeted herpesvirus having a heterologous polypeptide fused to glycoprotein H, wherein the polypeptide targets diseased cells. It also relates to a nucleic acid comprising the genome of the herpesvirus of the invention, a vector comprising this nucleic acid and a cell comprising the nucleic acid or the vector. It further relates to killing cells using the herpesvirus of the invention and to methods for growing it in vitro.

公开(公告)号：USPP27060P3

公开(公告)日：2016-08-16

申请号：US13987767

申请日：2013-08-29

申请人： ALMA MATER STUDIORUM—UNIVERSITA′ DI BOLOGNA ,  UNIVERSITA′ DEGLI STUDI DI UDINE

发明人： Guglielmo Costa ,  Raffaele Testolin ,  Guido Cipriani

IPC分类号： A01H5/08

CPC分类号： A01H5/08

摘要： A new and distinct Actinidia chinensis Planchon cultivar named AC1536 is disclosed, characterized by distinctive large, oblong fruit, and an earlier time of maturity for harvesting.

摘要翻译： 披露了一种新颖独特的中华猕猴桃品种AC1536，其特征是具有独特的大型长圆形果实，并且成熟期较早。

公开(公告)号：US08884069B2

公开(公告)日：2014-11-11

申请号：US13703618

申请日：2011-06-10

申请人： Giovanni Camera Roda ,  Vincenzo Augugliaro ,  Vittorio Loddo ,  Giovanni Palmisano ,  Leonardo Palmisano

发明人： Giovanni Camera Roda ,  Vincenzo Augugliaro ,  Vittorio Loddo ,  Giovanni Palmisano ,  Leonardo Palmisano

IPC分类号： C07C45/27 ,  C07C45/29 ,  B01J19/08 ,  B01J8/00 ,  C07C45/36 ,  C07C45/78 ,  C07C45/38

CPC分类号： C07C45/27 ,  C07C45/29 ,  C07C45/36 ,  C07C45/38 ,  C07C45/78 ,  C07C47/54 ,  C07C47/565 ,  C07C47/228 ,  C07C47/542 ,  C07C47/55 ,  C07C47/575

摘要： A process for the preparation of an aromatic aldehyde by means of the oxidation of the corresponding starting compound in aqueous medium, and separation of said aldehyde from said medium by pervaporation is disclosed together a plant for its carrying out. Advantageously, the process of the present invention allows control of oxidation reaction and recovery of the product with high selectivity and purity. Among others, benzaldehyde, anisaldehyde and vanillin can advantageously be prepared by this process.

摘要翻译： 通过在水性介质中氧化相应起始化合物并通过全蒸发从所述介质中分离醛的方法公开在一起用于其进行的设备。 有利地，本发明的方法允许以高选择性和纯度控制氧化反应和回收产物。 其中，苯甲醛，茴香醛和香草醛可有利地通过该方法制备。

公开(公告)号：US08771642B2

公开(公告)日：2014-07-08

申请号：US13056752

申请日：2009-07-31

申请人： Sara Bonacchi ,  Riccardo Juris ,  Marco Montalti ,  Luca Prodi ,  Enrico Rampazzo ,  Nelsi Zaccheroni

发明人： Sara Bonacchi ,  Riccardo Juris ,  Marco Montalti ,  Luca Prodi ,  Enrico Rampazzo ,  Nelsi Zaccheroni

IPC分类号： A61K49/00 ,  A61K9/16 ,  A01N55/00

CPC分类号： C07F15/0053 ,  A61K49/0021 ,  A61K49/0032 ,  A61K49/0041 ,  A61K49/0043 ,  A61K49/0093

摘要： Nanoparticles, which are luminescent and/or electroactive and/or suitable for MRI (magnetic resonance imaging and/or PET (positron emission tomography) applications, comprise a micelle, which has a hydrophilic shell and an hydrophobic central portion, and a polysilicate core; the micelle comprises a plurality of molecules of a functionalized surfactant having the following structure: M1-Hydro1-Lipo-Hydro2-M2 wherein Lipo indicates a hydrophobic chain; Hydro1 ed Hydro2 indicate, each, a respective hydrophilic chain; M1 ed M2 represent respective recognition functionalities.

摘要翻译： 发光和/或电活性和/或适合于MRI（磁共振成像和/或PET（正电子发射断层摄影）应用）的纳米颗粒包含具有亲水壳和疏水中心部分的胶束和聚硅酸盐芯; 胶束包含多个具有以下结构的官能化表面活性剂分子：M1-Hydro1-Lipo-Hydro2-M2其中Lipo表示疏水链; Hydro1 ed Hydro2分别表示相应的亲水链; M1 ed M2表示相应的识别 功能。

公开(公告)号：US20100183569A1

公开(公告)日：2010-07-22

申请号：US12665461

申请日：2008-06-27

申请人： Adriana Bigi ,  Silvia Panzavolta ,  Roberto Giardino ,  Milena Fini

发明人： Adriana Bigi ,  Silvia Panzavolta ,  Roberto Giardino ,  Milena Fini

IPC分类号： A61K35/12 ,  A61K38/18 ,  A61K31/715 ,  A61K33/42 ,  A61P19/00 ,  C12N11/10

CPC分类号： A61L27/56 ,  A61L27/46 ,  C08L5/00 ,  C08L89/00

摘要： The present invention refers to a porous composite material, wherein at least one interdispersed biopolymer is present, with a calcium-phosphate mineral component comprising from 50 w/% to 95 w/% of α-tricalcium phosphate (α-TCP, α-Ca3(PO4)2) and from 5 w/% to 50 w/% of octacalcium phosphate (OCP, Ca8H2(PO4)6—5H2O), to the total weight of the mineral component. Such combination of α-TCP and OCP allows an in vivo faster resorption rate and thereby a faster formation of new bone tissue having a low cristallinity mineral component with nanocrystal structure, features very similar to those of biological apatites. This porous composite material may find application as bone and/or osteal-chart ilagineous substitute (scaffold) and in producing tissue engineering devices.

摘要翻译： 本发明涉及一种多孔复合材料，其中存在至少一种分散间生物聚合物，其中磷酸钙矿物组分包含50w /％至95w /％的α-磷酸三钙（α-TCP，α-Ca 3 （PO4）2）和5w /％至50w /％的磷酸八钙（OCP，Ca8H2（PO4）6-5H2O））相对于矿物组分的总重量。 α-TCP和OCP的这种组合允许体内更快的再吸收速率，从而更快地形成具有纳米晶体结构的低cristallinity矿物组分的新骨组织，其特征与生物磷灰石的特征非常相似。 这种多孔复合材料可以用作骨和/或骨骼表示的替代物（支架）和用于生产组织工程装置。

公开(公告)号：US20240252701A1

公开(公告)日：2024-08-01

申请号：US18632473

申请日：2024-04-11

申请人： ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA

发明人： Paolo SERI ,  Gabriele NERETTI ,  Carlo Angelo BORGHI

IPC分类号： A61L2/14 ,  A61L101/02

CPC分类号： A61L2/14 ,  A61L2101/02 ,  A61L2202/11 ,  A61L2202/122 ,  A61L2202/14 ,  A61L2202/23

摘要： Sterilization method using plasma for sterilizing objects, wherein it is provided to introduce the objects to be sterilized into a sterilization chamber (13) and covey toward the latter a flow of air coming from a feed pipe (17) on which a plasma generator device (30) is disposed able to generate one or more gaseous compounds comprising a mixture of reactive oxygen species (ROS) and of reactive nitrogen species (RNS) so that the air is the carrier fluid which conveys the gaseous compounds toward the sterilization chamber (13); the method also provides to control the electric power used to produce the plasma as a function of the composition and/or the quantity of reactive species present in the sterilization chamber (13).

公开(公告)号：US11986765B2

公开(公告)日：2024-05-21

申请号：US17046741

申请日：2019-03-25

申请人： ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNA

发明人： Cesare Saccani ,  Augusto Bianchini

IPC分类号： B01D47/06 ,  B01D47/05 ,  B05B1/02 ,  B05B1/34 ,  F23J15/04

CPC分类号： B01D47/06 ,  B01D47/05 ,  B05B1/02 ,  B05B1/34 ,  F23J15/04 ,  F23J2217/50 ,  F23J2219/40 ,  F23J2219/70

摘要： The present invention relates to a method and to an apparatus for separating an exhaust gas, in particular an exhaust gas of a boiler, comprising introducing a gas stream of exhaust gas inside a washing chamber, dispensing a pressurized liquid shaped as drops inside the washing chamber, wherein the delivery pressure is adjusted according to the specific particulate to be separated so as to provide, during the separating step, a physical interaction between the delivered liquid drops and the particulate particles.

公开(公告)号：US20220259075A1

公开(公告)日：2022-08-18

申请号：US17626227

申请日：2020-07-13

申请人： CONSIGLIO NAZIONALE DELLE RICERCHE ,  ALMA MATER STUDIORUM UNIVERSITA' DI BOLOGNA

发明人： Sabrina Carola CARROCCIO ,  Francesca CUNSOLO ,  Tommaso MECCA ,  Vittorio PRIVITERA ,  Martina USSIA ,  Daniele CARETTI ,  Stefano SCURTI

IPC分类号： C02F1/28 ,  B01J20/26 ,  B01J20/28

摘要： The disclosure relates to N-alkyl-D-glucamine based macroporous polymeric cryogels with three-dimensional structure and with interconnected pores, which are used for sequestering and/or removing toxic contaminants, such as toxic metalloids and/or toxic heavy metals, for example from water and/or soil and the method for the preparation of said -alkyl-D-glucamine based macroporous polymeric cryogels.

公开(公告)号：US20220202333A1

公开(公告)日：2022-06-30

申请号：US17607313

申请日：2020-04-29

申请人： Giuseppe Arnaldo USAI ,  ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA ,  UNIVERSITA' DEGLI STUDI DI CAGLIARI

发明人： Giuseppe Arnaldo USAI ,  Erika SCAVETTA ,  Isacco GUALANDI ,  Beatrice FRABONI ,  Marta TESSAROLO ,  Annalisa BONFIGLIO ,  Danilo PANI ,  Eleonora SULAS

IPC分类号： A61B5/268 ,  C08G61/12 ,  C08K5/3445 ,  C08K5/41 ,  C09D5/24 ,  C09D7/63 ,  C09D165/00 ,  C09D11/52 ,  C09D11/102 ,  A61B5/256

摘要： The invention provides a composition for a conductive polymeric material suitable for the production of electrodes for recording electrophysiological signals, such as electrocardiogram (EGG), electromyogram (EMG), electroencephalogram (EEG), etc and signals related to the impedance variation of the body or skin, both deriving from active and passive measures (for example, breathing, electrodermal response, etc.). For this purpose a formulation containing FEDOT and ionic liquids has been developed. The formulation according to the invention can be used generically in the context of detecting bioelectric signals and can be applied on wearable items, in particular in fabric, such as for example garments of different shapes, so as to be in direct contact with the areas of the body subject to detection. The artifacts include diving artefacts, such as watertight suits, and for water sports and submarine surveys, artifacts used in the medical and health sector such as plasters, elastic support bands and adhesive support bands and textile articles, including special fabrics such as bioceramics.

公开(公告)号：US11142868B2

公开(公告)日：2021-10-12

申请号：US16316867

申请日：2017-07-12

申请人： UNIVERSITA′ DEGLI STUDI DEL PIEMONTE ORIENTALE “A. AVOGADRO” ,  ALMA MATER STUDIORUM—UNIVERSITA′ DI BOLOGNA

发明人： Ilaria Braschi ,  Chiara Bisio ,  Enrico Buscaroli ,  Daniele Bussini ,  Graziano Elegir ,  Leonardo Marchese

IPC分类号： D21C9/08 ,  D21H27/10 ,  D21H17/13 ,  D21C5/02 ,  D21H21/20 ,  B01J20/22 ,  B01J20/28 ,  B01J20/30 ,  B01J20/34 ,  D21C9/02 ,  B32B29/08 ,  D21H21/22

摘要： A use of organofunctionalized mesoporous silica for the production of recycled paper; the organofunctionalized mesoporous silica comprises a base mesoporous silica having, on its surface, groups having the following general formula (I), wherein Si1 is a silicon atom of the base mesoporous silica, R1 is a C1-C5 aliphatic; R2 is chosen in the group consisting of: a C1-C5 aliphatic and an oxygen atom bound with a silicon atom of the base mesoporous silica; and R3 is chosen in the group consisting of: a hydroxyl, a C1-C5 aliphatic and an oxygen atom bound with a silicon atom of the base mesoporous silica (I).