摘要:
A medical device system that is insertable in a body lumen for treating and/or preventing injury to a body lumen wall is disclosed. The system comprises a stent comprising a sidewall having a first edge and a second edge, and a balloon capable of being disposed within the sidewall. The balloon has a first end portion that is capable of contacting the first edge of the sidewall and a second end portion that is capable of contacting the second edge of the sidewall when the balloon is expanded. At least the first end portion of the balloon comprises a first biologically active material. When the balloon is expanded, the first end portion of the balloon extends axially beyond the first edge of the sidewall in order to deliver the first biologically active material to a portion of the body lumen wall that is adjacent to the first edge of the sidewall. Methods for deploying the system are also disclosed.
摘要:
A modular stent graft system and associated surgical methods are provided that incorporates an external stent-based locking mechanism to prevent disarticulation of the legs from the bifurcated graft as well as other features that overcome many of the difficulties of the prior art associated with delivering and securing the bifurcated grafts to the intended deployment site within the human aorta.
摘要:
The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.
摘要:
The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.