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    Pyrrolidine compounds and process of preparing
    14.
    再颁专利
    Pyrrolidine compounds and process of preparing 有权
    吡咯烷化合物及其制备方法

    公开(公告)号：USRE36607E

    公开(公告)日：2000-03-07

    申请号：US276220

    申请日：1999-03-25

    Applicant: Joachim Mittendorf ,  Peter Fey ,  Bodo Junge ,  Johannes Kaulen ,  Kai van Laak ,  Heinrich Meier ,  Rudolf Schohe-Loop

    Inventor： Joachim Mittendorf ,  Peter Fey ,  Bodo Junge ,  Johannes Kaulen ,  Kai van Laak ,  Heinrich Meier ,  Rudolf Schohe-Loop

    IPC: A61K31/4412 ,  A61P25/28 ,  C07D207/40 ,  C07D207/416 ,  C07D211/80 ,  C07D211/90 ,  C07D401/02 ,  C07D401/06 ,  C07D401/12 ,  C07D521/00

    CPC classification number: C07D207/416 ,  C07D211/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D401/06 ,  C07D401/12

    Abstract: This invention relates to benzolididene compounds of the formula ##STR1## in which R.sup.2 represents the radical ##STR2## in which R.sup.4 and R.sup.5 are identical or different and denote halogen, cyano, ethinyl, trifluoromethoxy, methylthio, nitro, trifluoromethyl or straight-chain or branched alkyl, alkenyl, alkinyl or alkoxy having up to 4 carbon atoms, and one of the substituents optionally represents hydrogen,or a salt thereof.[...]..Iadd., andA represents hydrogen or straight-chain or branched alkyl having up to 8 carbon atoms, or represents phenyl or benzyl which are optionally substituted one to three times by identical or different substituents from the series consisting of hydroxyl, nitro, halogen, cyano, carboxyl, trifluoromethyl, trifluoromethoxy, straight-chain or branched alkoxy having up to 6 carbon atoms or by a group of the formula --NR.sup.6 R.sup.7 or --SO.sub.2 R.sup.8, in whichR.sup.6 and R.sup.7 are identical or different and denote hydrogen, phenyl or straight-chain or branched alkyl having up to 5 carbon atomsandR.sup.8 denotes straight-chain or branched alkyl having up to 4 carbon atoms or phenyl. .Iaddend.

    Abstract translation: 本发明涉及下式的苯偶姻化合物，其中R 2表示其中R 4和R 5相同或不同并且表示卤素，氰基，乙炔基，三氟甲氧基，甲硫基，硝基，三氟甲基或直链或支链烷基，烯基，炔基 或具有至多4个碳原子的烷氧基，其中一个取代基任选代表氢或其盐[和]，A表示氢或具有至多8个碳原子的直链或支链烷基，或表示苯基或苄基， 任选地被羟基，硝基，卤素，氰基，羧基，三氟甲基，三氟甲氧基，具有至多6个碳原子的直链或支链烷氧基或通过下式的基团取代的相同或不同的取代基取代一至三次： -NR6R7或-SO2R8，其中R6和R7相同或不同，表示氢，苯基或具有至多5个碳原子的直链或支链烷基，R8表示直链 具有至多4个碳原子的直链或支链烷基或苯基。

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