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公开(公告)号：US10166143B2
公开(公告)日：2019-01-01
申请号：US14243629
申请日：2014-04-02
发明人： Paul T. Finger , Toby Welles
IPC分类号： A61M25/01 , A61N5/10 , A61M37/00 , A61F9/00 , A61N5/06 , A61F9/007 , A61F9/008 , A61B34/20 , A61B90/00
摘要： A light-guided, ophthalmic-treatment-system for administering therapeutic agents to, into or through the scleral wall of the eye globe using any one of a variety of therapeutic applicators in conjunction with either transcorneal or transpupillary viewing methods or both.
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公开(公告)号：US09827444B2
公开(公告)日：2017-11-28
申请号：US14243696
申请日：2014-04-02
发明人： Paul T. Finger , Toby Welles , Jaime Simon
CPC分类号： A61N5/1017 , A61K51/06 , A61K51/1251 , A61N2005/1019 , Y10T29/49826
摘要： An ophthalmic radiation device using a polymeric radiation-source implemented as either a polymer molecularly bonded with a radioisotope or a polymeric encasement of a radioisotope.
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公开(公告)号：US09165692B2
公开(公告)日：2015-10-20
申请号：US14243683
申请日：2014-04-02
发明人： Paul T. Finger , Toby Welles
IPC分类号： G21H1/00 , G21H3/00 , G21H5/00 , G21G4/06 , G21G4/00 , A61N5/10 , G21G4/08 , G21F3/00 , G21F5/015
CPC分类号： G21G4/06 , A61N5/10 , A61N5/1001 , A61N5/1028 , A61N2005/1019 , A61N2005/1094 , G21F3/00 , G21F5/015 , G21G4/00 , G21G4/08
摘要： A glass radiation-source with customized geometries to maximize receipt of radiation into treatment areas that is formed from either neutron-activated glass, radioisotopes molecularly bonded to glass, or radioisotopes encased within glass.
摘要翻译： 具有定制几何形状的玻璃辐射源，以最大限度地将辐射接收到由中子活化玻璃，分子结合到玻璃上的放射性同位素或包含在玻璃内的放射性同位素形成的处理区域中。
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公开(公告)号：US11865360B2
公开(公告)日：2024-01-09
申请号：US17505601
申请日：2021-10-19
发明人： Paul T. Finger , Toby Welles
IPC分类号： A61N5/10
CPC分类号： A61N5/1014 , A61N5/1007 , A61N5/1031 , A61N2005/1005 , A61N2005/1019
摘要： A method and system may include a therapeutic agent having a radioactive source enclosed by a container. The container may be placed within a cavity of a medical device for treating animal tissue. The method and system allows a radioactive source to be manufactured in such a manner so as to control and spatially modulate the delivery of radiation doses to a treatment area of animal tissue, such as for tissue of humans. From the container, radiation doses and/or a radiation field are produced by the radiation source. The geometry and size of the radiation doses are controlled by the geometry of the container and the geometry of the radiation source as well as the type, number, and geometry of holes/slots in either the source material and/or a surface of the container.
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公开(公告)号：US20230096064A1
公开(公告)日：2023-03-30
申请号：US17883542
申请日：2022-08-08
发明人： PAUL T. FINGER , Toby Welles , Jaime Simon
IPC分类号： A61N5/10 , C08K5/42 , C08G18/83 , C08F10/02 , A61K51/06 , C08G18/32 , C08G18/76 , C08G18/82 , C08G64/10 , C08G64/24
摘要： A polymeric radiation-source with customized geometries to maximize receipt of radiation into treatment areas that is formed from either radioisotopes molecularly bonded to a polymer or radioisotopes encased within a polymer.
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公开(公告)号：US11020000B2
公开(公告)日：2021-06-01
申请号：US16182352
申请日：2018-11-06
发明人： Paul T. Finger , Toby Welles
摘要： A luminescent ophthalmic device for administering therapeutic materials, the device having at least one luminescent marker disposed in proximity to a therapeutic agent applicator so as facilitate placement in a treatment position when viewed using transcorneal or transpupillary viewing methods.
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公开(公告)号：US10384078B2
公开(公告)日：2019-08-20
申请号：US14243703
申请日：2014-04-02
发明人： Paul T. Finger , Toby Welles , Jaime Simon
IPC分类号： A61N5/10 , A61K51/06 , C08K5/42 , C08G18/83 , C08F10/02 , C08G64/10 , C08G64/24 , C08G18/76 , C08G18/82 , C08G18/32
摘要： A polymeric radiation-source with customized geometries to maximize receipt of radiation into treatment areas that is formed from either radioisotopes molecularly bonded to a polymer or radioisotopes encased within a polymer.
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公开(公告)号：US20150182152A1
公开(公告)日：2015-07-02
申请号：US14243623
申请日：2014-04-02
发明人： Paul T. FINGER , Toby Welles
IPC分类号： A61B5/1459 , A61B3/14
CPC分类号： A61B3/14 , A61B3/0008 , A61F9/0008 , A61F9/0017
摘要： A luminescent ophthalmic device for administering therapeutic materials, the device having at least one luminescent marker disposed in proximity to a therapeutic agent applicator so as facilitate placement in a treatment position when viewed using transcorneal or transpupillary viewing methods.
摘要翻译： 一种用于施用治疗材料的发光眼科装置，该装置具有设置在治疗剂施用器附近的至少一个发光标记，以便在使用透角膜或透视观察方法观察时便于放置在治疗位置。
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公开(公告)号：US20150105605A1
公开(公告)日：2015-04-16
申请号：US14243671
申请日：2014-04-02
发明人： Paul T. FINGER , Toby Welles
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1017 , A61N2005/1019 , Y10T29/49826
摘要： An ophthalmic radiation device and method employing a glass radiation-source in which a radioisotope is implemented as either a neutron-activated radioisotope, or radioisotope molecularly bonded to glass or encased in an encasement material.
摘要翻译： 一种使用玻璃辐射源的眼科辐射装置和方法，其中放射性同位素被实施为中子激活的放射性同位素或与玻璃分子结合或包封在包装材料中的放射性同位素。
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公开(公告)号：US20150105601A1
公开(公告)日：2015-04-16
申请号：US14243696
申请日：2014-04-02
发明人： Paul T. Finger , Toby Welles , Jaime Simon
CPC分类号： A61N5/1017 , A61K51/06 , A61K51/1251 , A61N2005/1019 , Y10T29/49826
摘要： An ophthalmic radiation device using a polymeric radiation-source implemented as either a polymer molecularly bonded with a radioisotope or a polymeric encasement of a radioisotope.
摘要翻译： 使用聚合物辐射源的眼科放射装置，其被实施为与放射性同位素或放射性同位素的聚合物包分子结合的聚合物。
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