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公开(公告)号：US20200299409A1
公开(公告)日：2020-09-24
申请号：US16790656
申请日：2020-02-13
Applicant: Genentech, Inc.
Inventor： Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, Jr. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU
IPC: C07K16/32 , C07K16/28 , A61K39/395 , C07K16/30 , A61K45/06 , A61K31/573 , A61K47/68
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号：US20170369869A1
公开(公告)日：2017-12-28
申请号：US15690544
申请日：2017-08-30
Applicant: Genentech, Inc.
Inventor： Devin TESAR , Xiaocheng CHEN , Mark DENNIS , Isidro HOTZEL
CPC classification number: C12N15/1037 , C07K16/00 , C07K2319/02 , C07K2319/40 , C07K2319/735 , C12N15/70 , C12N15/74 , C12N15/85 , C12N2820/10 , C12N2820/55 , C12N2820/85 , C12N2830/42 , C12N2830/55 , C12N2830/85 , C12P21/02
Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
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公开(公告)号：US20170204194A1
公开(公告)日：2017-07-20
申请号：US15473242
申请日：2017-03-29
Applicant: Genentech, Inc.
Inventor： Xiaocheng CHEN , Mark S. DENNIS , Allen J. EBENS, Jr. , Teemu T. JUNTTILA , Robert F. KELLEY , Mary A. MATHIEU
CPC classification number: C07K16/32 , A61K31/573 , A61K39/39558 , A61K45/06 , A61K47/6881 , A61K2039/505 , C07K16/2809 , C07K16/2827 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2896 , C07K16/30 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/71 , C07K2317/73 , C07K2317/92
Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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