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公开(公告)号:US20030049622A1
公开(公告)日:2003-03-13
申请号:US09904956
申请日:2001-07-14
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin J. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , A61K038/17
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030044839A1
公开(公告)日:2003-03-06
申请号:US09902903
申请日:2001-07-10
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030036061A1
公开(公告)日:2003-02-20
申请号:US09909204
申请日:2001-07-18
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey William , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20020142467A1
公开(公告)日:2002-10-03
申请号:US10131053
申请日:2002-04-22
Applicant: Genentech, Inc.
Inventor: Jennie P. Mather , Axel Ullrich
IPC: C12P021/02 , C12N005/06 , C12N015/87
Abstract: A method for culturing a recombinant host cell comprising: determining a polypeptide factor for a polypeptide factor-dependent host cell; transforming said host cell with nucleic acid encoding said polypeptide factor; transforming the host cell with nucleic acid encoding a desired protein; and, culturing the transformed host cells in a medium lacking the polypeptide factor.
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公开(公告)号:US20020132240A1
公开(公告)日:2002-09-19
申请号:US09909320
申请日:2001-07-18
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20010000488A1
公开(公告)日:2001-04-26
申请号:US09728342
申请日:2000-12-01
Applicant: Genentech, Inc.
Inventor: Jennie P. Mather
IPC: C12P021/02 , C12N015/17 , C12P021/06 , C07K005/00 , C07K007/00 , C07K016/00 , C07K017/00 , A61K038/28 , C12N005/06 , C12N005/10
Abstract: A method for culturing a recombinant host cell comprising: determining a polypeptide factor for a polypeptide factor-dependent host cell; transforming said host cell with nucleic acid encoding said polypeptide factor; transforming the host cell with nucleic acid encoding a desired protein; and, culturing the transformed host cells in a medium lacking the polypeptide factor.
Abstract translation: 一种用于培养重组宿主细胞的方法,包括:确定多肽因子依赖性宿主细胞的多肽因子; 用编码所述多肽因子的核酸转化所述宿主细胞; 用编码所需蛋白质的核酸转化宿主细胞; 并且在缺乏多肽因子的培养基中培养转化的宿主细胞。
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公开(公告)号:US20030185846A1
公开(公告)日:2003-10-02
申请号:US10299937
申请日:2002-11-18
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K039/00 , C12N009/00 , C07H021/04 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , C07K14/705
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030180796A1
公开(公告)日:2003-09-25
申请号:US10066203
申请日:2002-02-01
Applicant: Genentech, Inc.
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12N005/06 , C12P021/02 , C07K014/435 , C07K016/40
CPC classification number: A61K38/17 , C07H21/04 , C07K14/435 , C07K16/40 , C12N5/06 , C12N9/00 , C12P21/02 , C12P21/06 , G01N33/53 , Y02A50/473
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030148371A1
公开(公告)日:2003-08-07
申请号:US09906777
申请日:2001-07-16
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , A61K038/17
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030148370A1
公开(公告)日:2003-08-07
申请号:US09904838
申请日:2001-07-13
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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