公开(公告)号：US11597960B2

公开(公告)日：2023-03-07

申请号：US16459336

申请日：2019-07-01

Applicant: General Electric Company

Inventor： Alex David Corwin ,  Erik Leeming Kvam ,  Christine Lynne Surrette ,  Brian Joseph Scherer ,  Pei-Hsin Kuo ,  Ralf Lenigk

IPC: C12Q1/14 ,  C12Q1/04 ,  C12M3/06 ,  C12Q1/06 ,  C12M1/32 ,  C12M1/34 ,  C12M1/00 ,  C12M1/04 ,  G01N21/01 ,  G06T7/00

Abstract: The present disclosure relates to approaches for assessing a sample or the presence of microorganisms. The sample, in certain implementations may be assessed for one or both of absence of microorganisms (sterility) and/or for concentration of said organisms (bio-burden). sample partition device may be employed that partitions the sample input volume into multiple discrete measurement zones with little or no loss of sample (e.g., zero-loss) and with little operator involvement, thereby reducing operator- and environment-based false positives.

公开(公告)号：US20210001336A1

公开(公告)日：2021-01-07

申请号：US16459363

申请日：2019-07-01

Applicant: General Electric Company

Inventor： Alex David Corwin ,  Erik Leeming Kvam ,  Christine Lynne Surrette ,  Brian Joseph Scherer ,  Pei-Hsin Kuo ,  Ralf Lenigk ,  Tyler John Hammond

IPC: B01L3/00 ,  C12Q1/06 ,  G01N1/28

Abstract: The present disclosure relates to a consumable sample partition device and it assembly and use. The sample partition device can be used to test a sample for absence of microorganisms (sterility) and/or for concentration of said organisms (bio-burden). The sample partition device partitions the sample input volume into multiple discrete measurement zones with little or no loss of sample (e.g., zero-loss) and with little operator involvement, thereby reducing operator- and environment-based false positives.

公开(公告)号：US20180345278A1

公开(公告)日：2018-12-06

申请号：US15611586

申请日：2017-06-01

Applicant: General Electric Company

Inventor： Christopher Michael Puleo ,  Christine Lynne Surrette ,  Erik Leeming Kvam ,  Steven Yuehin Go ,  Feng Chen ,  John Richard Nelson ,  Craig Patrick Galligan ,  Radislav Alexandrovich Potyrailo ,  Gregory Andrew Grossmann

IPC: B01L3/00 ,  C12Q1/02 ,  G01N21/64 ,  G01N21/76 ,  G01N33/554

CPC classification number: C12Q1/02 ,  C12M41/00 ,  C12M41/46 ,  C12Q1/18 ,  G01N21/6408 ,  G01N21/6452 ,  G01N33/4836

Abstract: A system includes a bacteria culture array that includes a plurality of chambers each configured to receive a portion of a sample that includes bacteria. Each individual chamber of the plurality of chambers includes a chamber opening configured to permit access of the portion of the sample to the individual chamber. The system also includes one or more sensors configured to collect data from the individual chamber. The sensors are configured to contact the sample. Additionally, the system includes a monitoring and analysis system that includes a processor configured to receive the data from the one or more sensors at a first time and a second time, compare the data received at the second time to the data received at the first time, and identify a portion of the plurality of chambers of the bacteria culture array based on the comparing.