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公开(公告)号：US11972874B2
公开(公告)日：2024-04-30
申请号：US18213194
申请日：2023-06-22
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , William Uhland , Brian Regna , Craig Brunkhorst
CPC classification number: G21G1/001 , A61K51/0482 , C01G3/003 , G21G1/10 , G21G4/08 , G21G2001/0094
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US20230352203A1
公开(公告)日：2023-11-02
申请号：US18213194
申请日：2023-06-22
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , William Uhland , Brian Regna , Craig Brunkhorst
CPC classification number: G21G1/001 , A61K51/0482 , C01G3/003 , G21G1/10 , G21G4/08 , G21G2001/0094
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US20240350679A1
公开(公告)日：2024-10-24
申请号：US18756231
申请日：2024-06-27
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , Shaun Loveless , Allan Casciola
CPC classification number: A61K51/0472 , A61K51/083
Abstract: The present disclosure relates to methods to create a robust procedure capable of supplying commercial quantities of a radioactive diagnostic agent indicated for use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) in adult patients.
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Patent Agency Ranking
公开(公告)号：US20240339235A1
公开(公告)日：2024-10-10
申请号：US18745896
申请日：2024-06-17
Applicant: Curium US LLC
Inventor： Brian Regna , Allan Casciola , Lauren Radford , Shaun Loveless , David Pipes , William Uhland , Craig Brunkhorst
CPC classification number: G21G1/001 , A61K51/0482 , C01G3/003 , G21G1/10 , G21G4/08 , G21G2001/0094
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US20230081594A1
公开(公告)日：2023-03-16
申请号：US17993186
申请日：2022-11-23
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , William Uhland , Brian Regna , Craig Brunkhorst
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US11581103B2
公开(公告)日：2023-02-14
申请号：US17894874
申请日：2022-08-24
Applicant: CURIUM US LLC
Inventor： David Pipes , Lauren Radford , William Uhland , Brian Regna , Craig Brunkhorst
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US11521762B2
公开(公告)日：2022-12-06
申请号：US17466443
申请日：2021-09-03
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , William Uhland , Brian Regna , Craig Brunkhorst
Abstract: Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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公开(公告)号：US20220080059A1
公开(公告)日：2022-03-17
申请号：US17467110
申请日：2021-09-03
Applicant: Curium US LLC
Inventor： David Pipes , Lauren Radford , Shaun Loveless , Allan Casciola
Abstract: The present disclosure relates to methods to create a robust procedure capable of supplying commercial quantities of a radioactive diagnostic agent indicated for use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) in adult patients.
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