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公开(公告)号:US20170103186A1
公开(公告)日:2017-04-13
申请号:US15315954
申请日:2015-06-03
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler , Basel Hasan Taha , Jimmie L. Ward , Steven William Badelt
CPC classification number: A61M5/20 , A61M5/14244 , A61M5/14248 , A61M5/158 , A61M5/24 , A61M5/31501 , A61M5/31568 , A61M5/3202 , A61M5/3243 , A61M5/3257 , A61M5/326 , A61M5/5086 , A61M2005/3267 , A61M2205/3331 , A61M2205/3368 , A61M2205/3553 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/6009 , G06F19/325 , G06F19/3418 , G06F19/3468 , G06Q50/01 , G06Q50/22
Abstract: Systems and methods are disclosed herein for supporting a patient's use of a drug delivery device. The patient may be associated with a support group via, for example, a social networking service for the purpose of increasing the likelihood that the patient will comply with a treatment regimen. Based on data representative of a condition and/or operational state of the drug delivery device, it may be determined whether the patient is compliant with the treatment regimen. If the patient is not compliant, the systems and method disclosed herein may transmit a communication to the support group requesting the support group to counsel the patient about the treatment regimen. The counseling may take the form of words of encouragement, coaching, suggestions, reminders, and/or any other communication likely to urge the patient to comply with the treatment regimen.
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公开(公告)号:US20240382673A1
公开(公告)日:2024-11-21
申请号:US18642384
申请日:2024-04-22
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Erich Coiner , Alan D. Payne
IPC: A61M5/142
Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.
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公开(公告)号:US20240277937A1
公开(公告)日:2024-08-22
申请号:US18645779
申请日:2024-04-25
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Basel Hasan Taha , Jimmie L. Ward , Christopher R. Folk , Steven William Badelt , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler
IPC: A61M5/20 , A61M5/142 , A61M5/158 , A61M5/24 , A61M5/315 , A61M5/32 , A61M5/50 , G06Q50/00 , G06Q50/22 , G16H20/17 , G16H40/00 , G16H40/63 , G16H40/67
CPC classification number: A61M5/20 , A61M5/14244 , A61M5/14248 , A61M5/158 , A61M5/24 , A61M5/31501 , A61M5/31568 , A61M5/3202 , A61M5/3243 , A61M5/3257 , A61M5/326 , A61M5/5086 , G06Q50/01 , G06Q50/22 , G16H20/17 , G16H40/00 , G16H40/63 , G16H40/67 , A61M2005/3267 , A61M2205/3331 , A61M2205/3368 , A61M2205/3553 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/6009
Abstract: A drug delivery system is disclosed that includes a drug delivery device having a reservoir, a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient, and one or more controllable elements. The drug delivery system may further include one or more sensors coupled to the drug delivery device, and a controller coupled to the one or more sensors and the one or more controllable elements. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device. Furthermore, the controller may be configured to control the controllable element based on the condition or the operational state of the drug delivery device and/or identity information stored in a memory onboard the device. A method for use with a drug delivery device is also disclosed.
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公开(公告)号:US11904143B2
公开(公告)日:2024-02-20
申请号:US16609466
申请日:2018-06-04
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号:US11583633B2
公开(公告)日:2023-02-21
申请号:US15944709
申请日:2018-04-03
Applicant: AMGEN INC.
Inventor: Scott Robert Gibson , Adam B. McCullough
Abstract: Systems and methods for delayed delivery of a drug are disclosed. A drug delivery system may include a delivery member for insertion into a patient and a reservoir configured to receive a volume of a drug. An energy source may be activatable by the patient to actuate the reservoir to deliver the drug to the patient as a single bolus. A lockout system may be configured to have a locked state, wherein the lockout system prevents movement of the delivery member and/or activation of the energy source, and an unlocked state, wherein the lockout system permits movement of the delivery member and/or activation of the energy source. The lockout system may be configured to automatically change from the locked state to the unlocked state after a preselected time period has elapsed. An output element may generate a detectable output after the preselected time period has elapsed for notifying the patient.
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公开(公告)号:US11464900B2
公开(公告)日:2022-10-11
申请号:US17099137
申请日:2020-11-16
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Erich Coiner , Alan D. Payne
IPC: A61M5/142
Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.
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公开(公告)号:US11357916B2
公开(公告)日:2022-06-14
申请号:US15522387
申请日:2015-12-10
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Scott R. Gibson
Abstract: A drug delivery device includes a container for storing a drug, the container having a stopper for expelling the drug; an injection drive comprising an energy source for directly or indirectly acting on the stopper to expel the drug; a sensor for detecting contact between the drug delivery device and a body of a patient; and a user interface (UI) for activating or causing the activation of the injection drive. The device is operative for drawing attention to the UI, if the sensor detects contact between the drug delivery device and the body of the patient, to thereby indicate that the injection drive is ready to be activated, which activation is the next step in the drug administration process.
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公开(公告)号:US11213624B2
公开(公告)日:2022-01-04
申请号:US16843622
申请日:2020-04-08
Applicant: AMGEN INC.
Inventor: Adam B. McCullough , Ferry Tamtoro , Huaying Yang , Mark Ka Lai Lee , Desheng Yin , Scott R. Gibson , Donald Busby , Peter V. Shultz , Keith P. Kogler , Basel Hasan Taha , Jimmie L. Ward , Christopher R. Folk , Steven William Badelt
IPC: A61M5/142 , A61M5/20 , A61M5/315 , A61M5/32 , A61M5/50 , G16H20/17 , G16H40/63 , G16H40/00 , G16H40/67 , G06Q50/22 , G06Q50/00 , A61M5/158 , A61M5/24
Abstract: A drug delivery system is disclosed that includes a drug delivery device having a reservoir, a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient, and one or more controllable elements. The drug delivery system may further include one or more sensors coupled to the drug delivery device, and a controller coupled to the one or more sensors and the one or more controllable elements. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device. Furthermore, the controller may be configured to control the controllable element based on the condition or the operational state of the drug delivery device and/or identity information stored in a memory onboard the device. A method for use with a drug delivery device is also disclosed.
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公开(公告)号:US11154661B2
公开(公告)日:2021-10-26
申请号:US16060555
申请日:2017-01-04
Applicant: AMGEN INC.
Inventor: Scott Robert Gibson , Donald Busby , Adam B. McCullough , Peter V. Shultz , Jimmie L. Ward , Huaying Yang , Desheng Yin , Steven William Badelt , Christopher R. Folk , Keith P. Kogler , Mark Ka Lai Lee , Ferry Tamtoro
Abstract: A drug delivery device includes a housing defining a shell comprising a front portion and a rear portion slidably coupled to the front portion, a drug delivery assembly at least partially disposed within the housing, at least one electronic component, a power source which powers the electronic component, and a switch assembly. The switch assembly is adapted to selectively cause the power source to provide power to the at least one electronic component.
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公开(公告)号:US20210077713A1
公开(公告)日:2021-03-18
申请号:US17099137
申请日:2020-11-16
Applicant: AMGEN INC,
Inventor: Adam B. McCullough , Erich Coiner , Alan D. Payne
IPC: A61M5/142
Abstract: An insertion mechanism for a drug delivery device including a trocar, a housing, and a manifold in fluid communication with a fluid pathway connector and movable relative to the housing between a first manifold position adjacent to a proximal end of the housing and a second manifold position adjacent to a distal end of the housing. A hub carrying the trocar or hollow delivery needle is removably connected to the manifold, the hub being movable relative to the housing between a first hub position adjacent to the proximal end of the housing and a second hub position adjacent to the distal end of the housing. A power source is configured to generate rotational motion. A motion conversion mechanism operatively connects the power source and the hub, and is configured to convert the rotational motion into linear motion of the hub.
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